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The map label for this gene is gpmB [H]

Identifier: 94309365

GI number: 94309365

Start: 445409

End: 446083

Strand: Direct

Name: gpmB [H]

Synonym: Rmet_0420

Alternate gene names: 94309365

Gene position: 445409-446083 (Clockwise)

Preceding gene: 94309364

Following gene: 94309381

Centisome position: 11.34

GC content: 69.63

Gene sequence:

>675_bases
ATGTCGCAAAGCACCGGCCCGCAATCGCTGGCCTACACCCACCTGATCGTGATTCGCCATGGCGAGACGGCCTGGAACCG
CGAACGGCGGCTGCAGGGCCAGCTCGACATCCCACTGAATGACACGGGCCGCGCCCAGGCGCGCGCGCTGGCCGAGGCGC
TGGCCGGCGAGCCGATCGACGCGGTCTATTCGAGTGACCTGGGCCGTGCCATGCAGACGGCGGCGCCGTTGGCCGAGACG
CTGGGTTTGCAAGTGCGGCCCGAGCGTCGACTGCGGGAGCGTTGCTATGGCGATCTGGAGGGGATGACCTACGCTGAAGT
GGCGGAGAAGCGCCCTGAGGATTTCGCGCGCTGGCAGGCGCGCGTGCCCGACTACGCGCCGCCCGAGGGCGAATCGCTGC
GCGAGTTTCACGATCGGGCGGTCGAGGTGGCGCTGTATCTGTCGCGGCGCCATCCTGGCGAGCGGATCGCGCTGGTGGCA
CACGGAGGCGTCCTCGACTGCCTCTACCGCGAGGCTGCCGGCATGACCCTCGAAGCGCCGCGCGAGCACGAACTGCTCAA
TGCCAGCGTCAACCGCCTGCGGTGCGACACCGCCCACCTCACGCTGCTGCAGTGGGCCGACGTCAGCCACCTCGAGGCGC
TGGCGCTGGACGAAGTCGATCGACGCGTCCCCTGA

Upstream 100 bases:

>100_bases
ACCGGCACATACACCCTTAACCCGAGGCTCGTGAAGTAACCTCGTTCGCCCCGCCGGGCGTCAGATCCGGCCCGAACCGT
CGCCCCCCGAGGAATCGGCA

Downstream 100 bases:

>100_bases
TACTCCTGATCCCCCTGATCCGATTCTCCGGGTCACGCCCTGGCGTCCTGCCGCGAGCGTCGGTGCAATAAAAAACTCCC
GGCCACGGCCGGGAGTTGTC

Product: phosphoglycerate mutase 2 protein

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSQSTGPQSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNDTGRAQARALAEALAGEPIDAVYSSDLGRAMQTAAPLAET
LGLQVRPERRLRERCYGDLEGMTYAEVAEKRPEDFARWQARVPDYAPPEGESLREFHDRAVEVALYLSRRHPGERIALVA
HGGVLDCLYREAAGMTLEAPREHELLNASVNRLRCDTAHLTLLQWADVSHLEALALDEVDRRVP

Sequences:

>Translated_224_residues
MSQSTGPQSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNDTGRAQARALAEALAGEPIDAVYSSDLGRAMQTAAPLAET
LGLQVRPERRLRERCYGDLEGMTYAEVAEKRPEDFARWQARVPDYAPPEGESLREFHDRAVEVALYLSRRHPGERIALVA
HGGVLDCLYREAAGMTLEAPREHELLNASVNRLRCDTAHLTLLQWADVSHLEALALDEVDRRVP
>Mature_223_residues
SQSTGPQSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNDTGRAQARALAEALAGEPIDAVYSSDLGRAMQTAAPLAETL
GLQVRPERRLRERCYGDLEGMTYAEVAEKRPEDFARWQARVPDYAPPEGESLREFHDRAVEVALYLSRRHPGERIALVAH
GGVLDCLYREAAGMTLEAPREHELLNASVNRLRCDTAHLTLLQWADVSHLEALALDEVDRRVP

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=145, Percent_Identity=35.1724137931034, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI50593010, Length=210, Percent_Identity=27.6190476190476, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI4502445, Length=124, Percent_Identity=34.6774193548387, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI40353764, Length=124, Percent_Identity=34.6774193548387, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI118582286, Length=156, Percent_Identity=32.6923076923077, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790856, Length=214, Percent_Identity=37.3831775700935, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786970, Length=201, Percent_Identity=31.3432835820896, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786857, Length=167, Percent_Identity=32.3353293413174, Blast_Score=71, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322697, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322306, Length=164, Percent_Identity=30.4878048780488, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646216, Length=145, Percent_Identity=33.1034482758621, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25108; Mature: 24976

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSTGPQSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNDTGRAQARALAEALAGEPID
CCCCCCCCHHEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHH
AVYSSDLGRAMQTAAPLAETLGLQVRPERRLRERCYGDLEGMTYAEVAEKRPEDFARWQA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHH
RVPDYAPPEGESLREFHDRAVEVALYLSRRHPGERIALVAHGGVLDCLYREAAGMTLEAP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEECCC
REHELLNASVNRLRCDTAHLTLLQWADVSHLEALALDEVDRRVP
CHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQSTGPQSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNDTGRAQARALAEALAGEPID
CCCCCCCHHEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHH
AVYSSDLGRAMQTAAPLAETLGLQVRPERRLRERCYGDLEGMTYAEVAEKRPEDFARWQA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHH
RVPDYAPPEGESLREFHDRAVEVALYLSRRHPGERIALVAHGGVLDCLYREAAGMTLEAP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEECCC
REHELLNASVNRLRCDTAHLTLLQWADVSHLEALALDEVDRRVP
CHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]