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The map label for this gene is dtd [H]

Identifier: 94309363

GI number: 94309363

Start: 444196

End: 444666

Strand: Direct

Name: dtd [H]

Synonym: Rmet_0418

Alternate gene names: 94309363

Gene position: 444196-444666 (Clockwise)

Preceding gene: 94309362

Following gene: 94309364

Centisome position: 11.31

GC content: 69.21

Gene sequence:

>471_bases
ATGATCGCCCTGATCCAGCGCGTTTCGCAGGCGCGCGTGACCGTGGATGGCCGCACCACCGGCGAGATCGGTGCGGGCCT
GCTGGCGCTGGTCTGTGCCGAGCGCGGCGACACCGAGGCGCAGGCCGAGCGATTGCTGGCCAAGCTGCTGTCGTACCGTG
TGTTTTCCGACGCGGAAGGGCGGATGAACCTGCCGGTGCAGAACATGGACGGCCAGGGCAACGCAGGCGGGCTGCTCGTG
GTGTCCCAGTTCACGCTGGCTGCCGATACCAACAGCGGCACCCGGCCGAGCTTCACCCCGGCTGCCGCGCCCGAGGACGG
CCGCCGCCTTTACGATCATTTCGTGACCCGCGCCCGCGCCGCGCATCCGTCGGTGCAGACCGGCGAGTTCGGCGCGATGA
TGCAGGTCAGCCTGACCAACGATGGTCCCGTGACGTTCTGGCTGCGCGTGCCACCGGCAGCGAATGCCTGA

Upstream 100 bases:

>100_bases
GTCAGCGACAAGTCGACCAAGGTGGTCGCCGGCACGTACGTGGTGCAGGTGGGCAAGCGCCGCTTCGCGCGCGTGACGCT
TTCCTGAGCCCGGGTCCGCG

Downstream 100 bases:

>100_bases
CGTCGCCCGAGATCGACACCCAAGGAGATCCCCATGAAACTCTGGAGCAAGGCCTTTGCCGACAATGCGCCGATTCCCGG
CGAGTTTGCGTTTTGCGTGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MIALIQRVSQARVTVDGRTTGEIGAGLLALVCAERGDTEAQAERLLAKLLSYRVFSDAEGRMNLPVQNMDGQGNAGGLLV
VSQFTLAADTNSGTRPSFTPAAAPEDGRRLYDHFVTRARAAHPSVQTGEFGAMMQVSLTNDGPVTFWLRVPPAANA

Sequences:

>Translated_156_residues
MIALIQRVSQARVTVDGRTTGEIGAGLLALVCAERGDTEAQAERLLAKLLSYRVFSDAEGRMNLPVQNMDGQGNAGGLLV
VSQFTLAADTNSGTRPSFTPAAAPEDGRRLYDHFVTRARAAHPSVQTGEFGAMMQVSLTNDGPVTFWLRVPPAANA
>Mature_156_residues
MIALIQRVSQARVTVDGRTTGEIGAGLLALVCAERGDTEAQAERLLAKLLSYRVFSDAEGRMNLPVQNMDGQGNAGGLLV
VSQFTLAADTNSGTRPSFTPAAAPEDGRRLYDHFVTRARAAHPSVQTGEFGAMMQVSLTNDGPVTFWLRVPPAANA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=158, Percent_Identity=37.3417721518987, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI1790320, Length=150, Percent_Identity=60, Blast_Score=179, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=37.1621621621622, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=42.6666666666667, Blast_Score=107, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281361569, Length=157, Percent_Identity=37.5796178343949, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16572; Mature: 16572

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSQARVTVDGRTTGEIGAGLLALVCAERGDTEAQAERLLAKLLSYRVFSDAEG
CHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
RMNLPVQNMDGQGNAGGLLVVSQFTLAADTNSGTRPSFTPAAAPEDGRRLYDHFVTRARA
EECCCEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AHPSVQTGEFGAMMQVSLTNDGPVTFWLRVPPAANA
CCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MIALIQRVSQARVTVDGRTTGEIGAGLLALVCAERGDTEAQAERLLAKLLSYRVFSDAEG
CHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
RMNLPVQNMDGQGNAGGLLVVSQFTLAADTNSGTRPSFTPAAAPEDGRRLYDHFVTRARA
EECCCEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AHPSVQTGEFGAMMQVSLTNDGPVTFWLRVPPAANA
CCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA