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The map label for this gene is arsC2 [H]

Identifier: 94309276

GI number: 94309276

Start: 349720

End: 350232

Strand: Reverse

Name: arsC2 [H]

Synonym: Rmet_0331

Alternate gene names: 94309276

Gene position: 350232-349720 (Counterclockwise)

Preceding gene: 94309277

Following gene: 94309275

Centisome position: 8.92

GC content: 60.43

Gene sequence:

>513_bases
ATGACCGACAAGACCTTCAACGTGCTGGTGCTGTGCACCGGCAACTCAGCCCGCAGCGTGATGGCCGAAGCGCTGTTCAA
TGTCCTCGGCAAGGGACGCTTTCACGCCTACAGCGCCGGCAGCCATCCATCTGGCACGGTCAATCCCTTCGCCATCGAAC
GATGCCAGGCAATTGGCTACGACACGACTGGCCTGCGTAGCAAGAGCTGGGACGAGTTCGCACTGCCCGATGCGCCCAGG
ATGGACTTCGTTATTACCGTCTGCGACCAAGCCGCAGGCGAGGTGTGCCCGATCTGGCCAGGTACACCCATCACGGCACA
TTGGGGCTTCCTCGACCCGGCAGCCATACAGGGCTCCGATGACGAGAAGCGCAAGATATTTGCCCAGGTTTTCCGGCAGA
TTCTGAATCGAGTCAGCCAGTTCGTGAACCTGCCGTTGCACGTGCTGGACCGGAACGCCATTCAGAAGGAGATGCACGCC
ATTGGCGAGCAACCCGTGGAGTCCGCGCAATGA

Upstream 100 bases:

>100_bases
CCGCCTGCTGTACGCCGGAATCCGGCTGCTGCTGAGCTTTCGCTAACGGCCTCCCGTACCGATACCTCGGGCGAGGAGGC
ACCCGCTCGCCCCTACGACC

Downstream 100 bases:

>100_bases
GCACGGCACAAAGGACGGCAGGAGCCTCCCAACCCAGTGCCATCGGCTTCTTCGAGCGCTATCTGACGGTCTGGGTGGCG
CTTTGCATCGTGGCCGGCAT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MTDKTFNVLVLCTGNSARSVMAEALFNVLGKGRFHAYSAGSHPSGTVNPFAIERCQAIGYDTTGLRSKSWDEFALPDAPR
MDFVITVCDQAAGEVCPIWPGTPITAHWGFLDPAAIQGSDDEKRKIFAQVFRQILNRVSQFVNLPLHVLDRNAIQKEMHA
IGEQPVESAQ

Sequences:

>Translated_170_residues
MTDKTFNVLVLCTGNSARSVMAEALFNVLGKGRFHAYSAGSHPSGTVNPFAIERCQAIGYDTTGLRSKSWDEFALPDAPR
MDFVITVCDQAAGEVCPIWPGTPITAHWGFLDPAAIQGSDDEKRKIFAQVFRQILNRVSQFVNLPLHVLDRNAIQKEMHA
IGEQPVESAQ
>Mature_169_residues
TDKTFNVLVLCTGNSARSVMAEALFNVLGKGRFHAYSAGSHPSGTVNPFAIERCQAIGYDTTGLRSKSWDEFALPDAPRM
DFVITVCDQAAGEVCPIWPGTPITAHWGFLDPAAIQGSDDEKRKIFAQVFRQILNRVSQFVNLPLHVLDRNAIQKEMHAI
GEQPVESAQ

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18689; Mature: 18558

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKTFNVLVLCTGNSARSVMAEALFNVLGKGRFHAYSAGSHPSGTVNPFAIERCQAIGY
CCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
DTTGLRSKSWDEFALPDAPRMDFVITVCDQAAGEVCPIWPGTPITAHWGFLDPAAIQGSD
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHCCCCEECCCCCCCCEEECCCCCCHHCCCCC
DEKRKIFAQVFRQILNRVSQFVNLPLHVLDRNAIQKEMHAIGEQPVESAQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDKTFNVLVLCTGNSARSVMAEALFNVLGKGRFHAYSAGSHPSGTVNPFAIERCQAIGY
CCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
DTTGLRSKSWDEFALPDAPRMDFVITVCDQAAGEVCPIWPGTPITAHWGFLDPAAIQGSD
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHCCCCEECCCCCCCCEEECCCCCCHHCCCCC
DEKRKIFAQVFRQILNRVSQFVNLPLHVLDRNAIQKEMHAIGEQPVESAQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]