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The map label for this gene is arsC1 [H]

Identifier: 94309274

GI number: 94309274

Start: 348227

End: 348649

Strand: Reverse

Name: arsC1 [H]

Synonym: Rmet_0329

Alternate gene names: 94309274

Gene position: 348649-348227 (Counterclockwise)

Preceding gene: 94309275

Following gene: 94309273

Centisome position: 8.88

GC content: 61.23

Gene sequence:

>423_bases
ATGACCGTCACCATCTATCACAACCCCGCGTGCGGTACGTCACGCAATACGCTAGCCATGATCCGCAATGCGGGCATCGA
GCCGATTGTCGTCGAATACCTGAACATGCCGCCGGACCGGCAGACCTTGCAGTCGATGATCCGCGCCGCCGGTCTCTCCG
TGCGCGAAGCAATCCGCGAGAAAGGCACGCCCTACGCCGAGCTTGGCCTCGGCGATCCTGCACTGACCGACGACCAGTTG
CTTGATGCGATGCTGGCCCATCCGATCCTGATCAATCGGCCCTTTGTCATCACTGAGCTTGGTGTGCGGTTATGCAGGCC
GTCGGAAGTCGTGCTGGATATCCTGCCGGCGCCGCAGCAAGGTGCTTTCACCAAGGAGGACGGCGAGGCCGTGATCGACA
CACAAGGCCGGAGGATACGATGA

Upstream 100 bases:

>100_bases
CACCGTCGTCGGCGTGCTGATCGAAGTGCCGGTGATGCTCTTCGTAGTGGGCGTCGTGAACCGCTCGCAGCACTGGTACG
AATCGCACTGAGGTATCCCC

Downstream 100 bases:

>100_bases
CCGTGGATCTGCCCAATATTGTCCCTGCGGTGCTCGATACGCCTGACCTCAGTAAGCTGGAGCCGGCACGCGCCAGCACA
CACCCGCCGCGCATCCTGCT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTVTIYHNPACGTSRNTLAMIRNAGIEPIVVEYLNMPPDRQTLQSMIRAAGLSVREAIREKGTPYAELGLGDPALTDDQL
LDAMLAHPILINRPFVITELGVRLCRPSEVVLDILPAPQQGAFTKEDGEAVIDTQGRRIR

Sequences:

>Translated_140_residues
MTVTIYHNPACGTSRNTLAMIRNAGIEPIVVEYLNMPPDRQTLQSMIRAAGLSVREAIREKGTPYAELGLGDPALTDDQL
LDAMLAHPILINRPFVITELGVRLCRPSEVVLDILPAPQQGAFTKEDGEAVIDTQGRRIR
>Mature_139_residues
TVTIYHNPACGTSRNTLAMIRNAGIEPIVVEYLNMPPDRQTLQSMIRAAGLSVREAIREKGTPYAELGLGDPALTDDQLL
DAMLAHPILINRPFVITELGVRLCRPSEVVLDILPAPQQGAFTKEDGEAVIDTQGRRIR

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=139, Percent_Identity=61.1510791366906, Blast_Score=185, Evalue=8e-49,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=42.9824561403509, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15361; Mature: 15230

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIYHNPACGTSRNTLAMIRNAGIEPIVVEYLNMPPDRQTLQSMIRAAGLSVREAIRE
CEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHH
KGTPYAELGLGDPALTDDQLLDAMLAHPILINRPFVITELGVRLCRPSEVVLDILPAPQQ
CCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCCHHEEEECCCCCC
GAFTKEDGEAVIDTQGRRIR
CCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TVTIYHNPACGTSRNTLAMIRNAGIEPIVVEYLNMPPDRQTLQSMIRAAGLSVREAIRE
EEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHH
KGTPYAELGLGDPALTDDQLLDAMLAHPILINRPFVITELGVRLCRPSEVVLDILPAPQQ
CCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCCHHEEEECCCCCC
GAFTKEDGEAVIDTQGRRIR
CCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]