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The map label for this gene is hprK [H]

Identifier: 94309244

GI number: 94309244

Start: 316242

End: 317213

Strand: Reverse

Name: hprK [H]

Synonym: Rmet_0299

Alternate gene names: 94309244

Gene position: 317213-316242 (Counterclockwise)

Preceding gene: 94309245

Following gene: 94309243

Centisome position: 8.08

GC content: 64.61

Gene sequence:

>972_bases
ATGGAACTCACCGGCGTCACCTCCCAGTCGATCTTCGACGACAACGCAGCCGACATCAAACTCTCCTGGGTCGCCGGTCT
GGAAGGGGCCGATCGTGCCTTCGACGTGGAATTCGCGCGGGAGGCAACATCGGCTGCCGATCTGGTCGGCCACCTGAACC
TGATCCACCCGAACCGGATTCAGGTACTCGGCAAACCCGAGATCCTTTACTACCAGCGCCTCGACGACGAACCCCGCAAG
CGTCAGATGGGCGAGCTGATCCTGCTGGAGCCGCCATTCCTGGTGGTGGCGGATGGCATGGAGCCGCCGCCCGACCTGGA
ACTGCGCTGCACGCGCTCATCGACTCCACTGTTCACGACGCCGGTATCCTCGGCGGCCGTCATCGACCACCTCCGCCTGT
ACCTGTCGCGCATCTCCGCACCGCGCGTCACCATGCACGGCGTGTTCCTCGACATCCTCGGCATGGGCGTGCTGATCATG
GGTGAGTCGGGCCTTGGCAAGAGCGAACTGGGCCTGGAACTGATCTCGCGCGGACACGGCCTGGTGGCCGACGACGCCGT
CGATTTCGTGCGGCTTGGCCCGGATTTCATTGAGGGCCGCTGCCCGCCGCTGCTGCAGAACCTGCTTGAAGTCCGCGGCC
TGGGCCTGCTCGACATCAAGACGATCTTCGGTGAGACCGCCGTGCGGCGGAAGATGAAGCTCAAGCTCGTGGTGCAATTG
GTGCGCCGCAACGACGGCGAGTTCGAGCGCCTGCCGCTTGATTCCCAGTACCTCGACGTTCTTGGCCTCCCGATCCACAT
GGTGAAGATCCAGGTGGCAGCCGGCCGAAACCTCGCCGTGCTGGTGGAAGCCGCCGTCCGCAACACGATACTGCGCCTGC
GCGGCATCGATACCCTCCGCGACTTCATGGATCGTCAGCGGGCAGCAATGCAGGCTGACGTGGTTTCCCGCGGCCAGGGT
CGGCTGCTCTGA

Upstream 100 bases:

>100_bases
TCCACGAGTTACTGACCCAGTGGCACCCCTGACACGACGGCAGGCCAGCGCAGCCTGACGCGATACCCGCGATACAGCCC
CTCCCGAAAAGTCATCCCGC

Downstream 100 bases:

>100_bases
TCAGACAATTCCGGCAGTTTTGTGAAACGCCGGCGTCGCTTTCAATTGCTTACAAGCGGCCGGCCTCCCCTCGTCAACGC
GCTTTGGGCGTGCGCCGTTT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEILYYQRLDDEPRK
RQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLVVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADVVSRGQG
RLL

Sequences:

>Translated_323_residues
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEILYYQRLDDEPRK
RQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLVVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADVVSRGQG
RLL
>Mature_323_residues
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEILYYQRLDDEPRK
RQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLVVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADVVSRGQG
RLL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35714; Mature: 35714

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRI
CCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEILYYQRLDDEPRKRQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTT
EEECCCCEEEEECCCCCHHHHHCCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCEEEC
PVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGESGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLVVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQADVVSRGQGRLL
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRI
CCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEILYYQRLDDEPRKRQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTT
EEECCCCEEEEECCCCCHHHHHCCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCEEEC
PVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGESGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLVVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQADVVSRGQGRLL
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA