Click here to switch to the map view.

The map label for this gene is manX [C]

Identifier: 94309189

GI number: 94309189

Start: 261267

End: 261722

Strand: Direct

Name: manX [C]

Synonym: Rmet_0244

Alternate gene names: 94309189

Gene position: 261267-261722 (Clockwise)

Preceding gene: 94309188

Following gene: 94309190

Centisome position: 6.65

GC content: 64.25

Gene sequence:

>456_bases
ATGGCAGGAATTCTGATCATCGCTCATGCGCCACTGGCTTCGGCGCTGCGCGATTGCGCTGGCCACGTCTACTGCGGCCA
GCCGCAGCGGGTGGAGGCGATCGACGTTATCGCCGATGCCGACCCTGCGGCGGTGCTGGCCGAGGCGCGGAAGCGTCTCG
CAGACGTTTGCGAAGAGAACGGCGCCCTGGTGCTGACCGATATCTTCGGCGCTACGCCTGCCAATATCGCCGCGCGGCTT
GCCGAGCCGGGTCGGGTCAAGGTGCTGGCCGGTGTCAACCTGCCGATGCTCGTGCGCGCTATCTGCTATCGGACGGAGAA
GCTCGACCAGCTTGCCACCAAGGCCTTGGCCGGAGGCGCCCAGGGCGTGCTGCAAATCGGCACGACCGCCGTCCAGAACC
AAACCGCAAATCATCCCGACAAATATGCTGCAGAGGGACACCACCATCATCAATAA

Upstream 100 bases:

>100_bases
CGCCGATGTTCAGGCGCCACAGTTGGCGCGGCGGGCGGGGCTGCGGATTGGGCGGTCAGGCTGCCTGCTACAATTCGGGC
AGTCCAACGGATTCACCATC

Downstream 100 bases:

>100_bases
GCTCGGGCTTCATGCCCGCGCATCCGCCAAGCTCACGCAGTTGGCAGGTAGCTTCAACAGCCAGGTCAAGATGTCCCGTA
ACGGCCGCCAGGTCGACGCC

Product: phosphotransferase system, fructose-specific component IIA

Products: protein histidine; sugar phosphate

Alternate protein names: IIA Component Of Sugar Transport PTS System; PTS System Fructose-Specific IIA Component; PTS System Fructose Subfamily Transporter Subunit IIA; Protein-N P-Phosphohistidine-Sugar Phosphotransferase; Sugar Transport PTS System IIA Component; PTS System Fructose IIA Component Family Protein; Pts System Fructose Subfamily IIa Component; PTS System Fructose IIA Component; Pts System IIa Component; Pentitol Phosphotransferase IIA Component; Phosphotransferase Mannose/Fructose-Specific Component IIA; PTS System Mannose/Fructose-Specific IIA Component

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MAGILIIAHAPLASALRDCAGHVYCGQPQRVEAIDVIADADPAAVLAEARKRLADVCEENGALVLTDIFGATPANIAARL
AEPGRVKVLAGVNLPMLVRAICYRTEKLDQLATKALAGGAQGVLQIGTTAVQNQTANHPDKYAAEGHHHHQ

Sequences:

>Translated_151_residues
MAGILIIAHAPLASALRDCAGHVYCGQPQRVEAIDVIADADPAAVLAEARKRLADVCEENGALVLTDIFGATPANIAARL
AEPGRVKVLAGVNLPMLVRAICYRTEKLDQLATKALAGGAQGVLQIGTTAVQNQTANHPDKYAAEGHHHHQ
>Mature_150_residues
AGILIIAHAPLASALRDCAGHVYCGQPQRVEAIDVIADADPAAVLAEARKRLADVCEENGALVLTDIFGATPANIAARLA
EPGRVKVLAGVNLPMLVRAICYRTEKLDQLATKALAGGAQGVLQIGTTAVQNQTANHPDKYAAEGHHHHQ

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 15797; Mature: 15666

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGILIIAHAPLASALRDCAGHVYCGQPQRVEAIDVIADADPAAVLAEARKRLADVCEEN
CCCEEEEECCCHHHHHHHHCCCEECCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHCC
GALVLTDIFGATPANIAARLAEPGRVKVLAGVNLPMLVRAICYRTEKLDQLATKALAGGA
CCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
QGVLQIGTTAVQNQTANHPDKYAAEGHHHHQ
CHHHHHCCHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
AGILIIAHAPLASALRDCAGHVYCGQPQRVEAIDVIADADPAAVLAEARKRLADVCEEN
CCEEEEECCCHHHHHHHHCCCEECCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHCC
GALVLTDIFGATPANIAARLAEPGRVKVLAGVNLPMLVRAICYRTEKLDQLATKALAGGA
CCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
QGVLQIGTTAVQNQTANHPDKYAAEGHHHHQ
CHHHHHCCHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA