BacMap

Definition	Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession	NC_007973
Length	3,928,089

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The map label for this gene is livG8 [H]

Identifier: 94309160

GI number: 94309160

Start: 228774

End: 229715

Strand: Direct

Name: livG8 [H]

Synonym: Rmet_0215

Alternate gene names: 94309160

Gene position: 228774-229715 (Clockwise)

Preceding gene: 94309159

Following gene: 94309161

Centisome position: 5.82

GC content: 65.18

Gene sequence:

>942_bases
ATGACGGTCACCCAGACAGCGTGGCAAGGCGGCATGGCCCGCGTGGACGCCACAGGCACGTTGGTGCCGCCGGGCGCGAT
TGCCCCGGCCGGGCACGTGGAGGGCACGCACGGCGACAGCCCGCGCCCCGGCAGTGCGCGTGAGCCAGAGTCGACGTCCC
ACGTTCGCACGCGCGGCGACGTGATTCTCGATCTGCAGAACATCTCGCTGTCGTTCGGCGGCGTGAAGGCGCTGACCGAT
ATCTCGTTCGACGTCTGCGAGCACGAGATCCGCGCAATCATCGGCCCGAACGGCGCGGGCAAGAGTTCGATGCTGAATGT
GATCAACGGCGTCTATCACCCGCAGCAGGGCCGCATCGTGTTTCGAGGCCAGGAGCGTCGCCAGATGCATCCCACGGCTG
CTGCGCGCCAGGGCATCGCACGGACGTTCCAGAACATCGCGCTGTTCAAGGGCATGACCGTGCTGGACAACATCATGACC
GGCCGCAACACGCAGTTCCGCACGGGCGTGTTCGCCCACGCGCTCTGGTGGGGGCCGGCCCGCGCCGAAGAGATGCGTCA
TCGCCGCAAGGTCGAGGAGGTGATCGACTTCCTCGAGATCCAGGCGATCCGCAAGACACCGGTCGGCAGGCTGCCTTACG
GCCTGCAGAAGCGCGTGGAACTGGCGCGCGCGCTGGCTGCGGAACCGTCGATGCTGTTGCTCGATGAACCGATGGCGGGC
ATGAACGTGGAAGAGAAGCAGGACATGTGCCGTTTCATCCTGGACGTGAACCATCAGTTCGGCACCACCATCGTGCTGAT
CGAGCACGACATGGGCGTGGTGATGGATATCTCCGACCGCGTGGTGGTACTCGACTACGGCAAGAAGATCGGCGATGGCA
CGCCCGATGAGGTCAAGTCGAACCCGGACGTGATTCGCGCATACCTCGGCACGGCGCACTGA

Upstream 100 bases:

>100_bases
GGGCGCGAGGGCAGCGTGTCGGCCACGCTGAAGCTGGTGGATGTGAAGCGCTTCCCGCCCGTAGGCGGCGCGCGCGCGGC
GTGAGCACGGAGGGTATGGC

Downstream 100 bases:

>100_bases
GCGCCCCGGGGTCATAGAGAGCATTGAGAGGATAGCGGCGATGAGTTTCTTCTTCGAAATCCTGATCGGCGGCTTGCTGT
CAGGACTGATGTACTCGCTC

Product: leucine/isoleucine/valine ABC transporter ATP-binding protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein G [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTVTQTAWQGGMARVDATGTLVPPGAIAPAGHVEGTHGDSPRPGSAREPESTSHVRTRGDVILDLQNISLSFGGVKALTD
ISFDVCEHEIRAIIGPNGAGKSSMLNVINGVYHPQQGRIVFRGQERRQMHPTAAARQGIARTFQNIALFKGMTVLDNIMT
GRNTQFRTGVFAHALWWGPARAEEMRHRRKVEEVIDFLEIQAIRKTPVGRLPYGLQKRVELARALAAEPSMLLLDEPMAG
MNVEEKQDMCRFILDVNHQFGTTIVLIEHDMGVVMDISDRVVVLDYGKKIGDGTPDEVKSNPDVIRAYLGTAH

Sequences:

>Translated_313_residues
MTVTQTAWQGGMARVDATGTLVPPGAIAPAGHVEGTHGDSPRPGSAREPESTSHVRTRGDVILDLQNISLSFGGVKALTD
ISFDVCEHEIRAIIGPNGAGKSSMLNVINGVYHPQQGRIVFRGQERRQMHPTAAARQGIARTFQNIALFKGMTVLDNIMT
GRNTQFRTGVFAHALWWGPARAEEMRHRRKVEEVIDFLEIQAIRKTPVGRLPYGLQKRVELARALAAEPSMLLLDEPMAG
MNVEEKQDMCRFILDVNHQFGTTIVLIEHDMGVVMDISDRVVVLDYGKKIGDGTPDEVKSNPDVIRAYLGTAH
>Mature_312_residues
TVTQTAWQGGMARVDATGTLVPPGAIAPAGHVEGTHGDSPRPGSAREPESTSHVRTRGDVILDLQNISLSFGGVKALTDI
SFDVCEHEIRAIIGPNGAGKSSMLNVINGVYHPQQGRIVFRGQERRQMHPTAAARQGIARTFQNIALFKGMTVLDNIMTG
RNTQFRTGVFAHALWWGPARAEEMRHRRKVEEVIDFLEIQAIRKTPVGRLPYGLQKRVELARALAAEPSMLLLDEPMAGM
NVEEKQDMCRFILDVNHQFGTTIVLIEHDMGVVMDISDRVVVLDYGKKIGDGTPDEVKSNPDVIRAYLGTAH

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0411

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=216, Percent_Identity=28.2407407407407, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI47078218, Length=227, Percent_Identity=25.1101321585903, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45446740, Length=227, Percent_Identity=25.1101321585903, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI31657092, Length=282, Percent_Identity=25.886524822695, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27477115, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27262624, Length=196, Percent_Identity=28.0612244897959, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27262626, Length=196, Percent_Identity=28.0612244897959, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436953, Length=216, Percent_Identity=24.537037037037, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI215820660, Length=302, Percent_Identity=23.1788079470199, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20143975, Length=302, Percent_Identity=23.1788079470199, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27881501, Length=239, Percent_Identity=24.2677824267782, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI30795238, Length=239, Percent_Identity=24.2677824267782, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI105990541, Length=228, Percent_Identity=22.3684210526316, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI21536376, Length=226, Percent_Identity=23.8938053097345, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789864, Length=254, Percent_Identity=38.9763779527559, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1788761, Length=240, Percent_Identity=31.25, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87081791, Length=254, Percent_Identity=28.740157480315, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789991, Length=252, Percent_Identity=32.5396825396825, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788210, Length=248, Percent_Identity=30.6451612903226, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788450, Length=254, Percent_Identity=28.3464566929134, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI48995001, Length=233, Percent_Identity=30.0429184549356, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790467, Length=240, Percent_Identity=30.4166666666667, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788472, Length=240, Percent_Identity=28.75, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790190, Length=233, Percent_Identity=30.0429184549356, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789032, Length=250, Percent_Identity=30, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786398, Length=247, Percent_Identity=29.5546558704453, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790525, Length=249, Percent_Identity=28.5140562248996, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081709, Length=254, Percent_Identity=25.9842519685039, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789672, Length=262, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789593, Length=248, Percent_Identity=29.8387096774194, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787029, Length=247, Percent_Identity=27.1255060728745, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1787712, Length=253, Percent_Identity=25.296442687747, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081782, Length=247, Percent_Identity=27.9352226720648, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787370, Length=241, Percent_Identity=26.9709543568465, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790739, Length=245, Percent_Identity=28.9795918367347, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082267, Length=241, Percent_Identity=27.8008298755187, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082268, Length=251, Percent_Identity=29.0836653386454, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786345, Length=249, Percent_Identity=27.3092369477912, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786872, Length=247, Percent_Identity=27.5303643724696, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788225, Length=248, Percent_Identity=27.4193548387097, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789962, Length=235, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786563, Length=226, Percent_Identity=28.3185840707965, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789586, Length=253, Percent_Identity=28.8537549407115, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994997, Length=247, Percent_Identity=27.5303643724696, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786253, Length=230, Percent_Identity=30, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994943, Length=241, Percent_Identity=26.1410788381743, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786319, Length=210, Percent_Identity=29.5238095238095, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787500, Length=233, Percent_Identity=28.3261802575107, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787089, Length=236, Percent_Identity=28.8135593220339, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786803, Length=243, Percent_Identity=23.4567901234568, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787758, Length=260, Percent_Identity=24.2307692307692, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788897, Length=215, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693107, Length=253, Percent_Identity=25.296442687747, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788644, Length=259, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787792, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789873, Length=229, Percent_Identity=27.5109170305677, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787759, Length=262, Percent_Identity=26.3358778625954, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789891, Length=215, Percent_Identity=28.8372093023256, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786698, Length=230, Percent_Identity=26.5217391304348, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790544, Length=247, Percent_Identity=24.2914979757085, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=25.5924170616114, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994883, Length=272, Percent_Identity=24.6323529411765, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790162, Length=247, Percent_Identity=24.6963562753036, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786975, Length=263, Percent_Identity=25.8555133079848, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787143, Length=250, Percent_Identity=25.6, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788053, Length=229, Percent_Identity=24.8908296943231, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786703, Length=214, Percent_Identity=25.7009345794392, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789963, Length=250, Percent_Identity=24.4, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788506, Length=277, Percent_Identity=25.6317689530686, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=257, Percent_Identity=25.2918287937743, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786981, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788002, Length=257, Percent_Identity=26.0700389105058, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787182, Length=241, Percent_Identity=24.0663900414938, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=259, Percent_Identity=25.4826254826255, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=245, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71984940, Length=224, Percent_Identity=27.6785714285714, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=264, Percent_Identity=24.6212121212121, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=248, Percent_Identity=22.5806451612903, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=263, Percent_Identity=23.574144486692, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648314, Length=288, Percent_Identity=25, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221512771, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24666092, Length=230, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI116007184, Length=235, Percent_Identity=22.1276595744681, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221500365, Length=235, Percent_Identity=22.1276595744681, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28571209, Length=219, Percent_Identity=22.8310502283105, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643674, Length=274, Percent_Identity=22.6277372262774, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573571, Length=238, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363262, Length=263, Percent_Identity=24.7148288973384, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24653245, Length=263, Percent_Identity=24.7148288973384, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 34377; Mature: 34246

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTQTAWQGGMARVDATGTLVPPGAIAPAGHVEGTHGDSPRPGSAREPESTSHVRTRGD
CCCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
VILDLQNISLSFGGVKALTDISFDVCEHEIRAIIGPNGAGKSSMLNVINGVYHPQQGRIV
EEEEEECCEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCEEE
FRGQERRQMHPTAAARQGIARTFQNIALFKGMTVLDNIMTGRNTQFRTGVFAHALWWGPA
EECCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCH
RAEEMRHRRKVEEVIDFLEIQAIRKTPVGRLPYGLQKRVELARALAAEPSMLLLDEPMAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
MNVEEKQDMCRFILDVNHQFGTTIVLIEHDMGVVMDISDRVVVLDYGKKIGDGTPDEVKS
CCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCEEEEECCCCCCCCCCHHHCC
NPDVIRAYLGTAH
CHHHHHHHHCCCC
>Mature Secondary Structure 
TVTQTAWQGGMARVDATGTLVPPGAIAPAGHVEGTHGDSPRPGSAREPESTSHVRTRGD
CCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
VILDLQNISLSFGGVKALTDISFDVCEHEIRAIIGPNGAGKSSMLNVINGVYHPQQGRIV
EEEEEECCEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCEEE
FRGQERRQMHPTAAARQGIARTFQNIALFKGMTVLDNIMTGRNTQFRTGVFAHALWWGPA
EECCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCH
RAEEMRHRRKVEEVIDFLEIQAIRKTPVGRLPYGLQKRVELARALAAEPSMLLLDEPMAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
MNVEEKQDMCRFILDVNHQFGTTIVLIEHDMGVVMDISDRVVVLDYGKKIGDGTPDEVKS
CCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCEEEEECCCCCCCCCCHHHCC
NPDVIRAYLGTAH
CHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]