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The map label for this gene is yhdG [H]

Identifier: 94309152

GI number: 94309152

Start: 217473

End: 218882

Strand: Direct

Name: yhdG [H]

Synonym: Rmet_0207

Alternate gene names: 94309152

Gene position: 217473-218882 (Clockwise)

Preceding gene: 94309151

Following gene: 94309154

Centisome position: 5.54

GC content: 64.54

Gene sequence:

>1410_bases
ATGAGTCTCTTTCGCACCAAAAACATCGACGCCATGCTGGAAGTCAGCGAGCACGACGGATTGCGAAAGGTGCTGGGGGC
GGTGGATCTGGTGCTGATGGGTATCGGGGCCATCATCGGCACCGGGATTTTCGTGCTGACTGGCACCGGGGCGCTGACCG
CGGGCCCCGCGCTGACGGTGTCGTTCGTGATCGCGGCCATGGCCTGCGGCTTCGCGGCGCTGTGCTATGCGGAGTTCGCT
TCCGCGATCCCCGTATCGGGTTCGATCTACACGTATAGCTACGCCACGCTCGGCGAGATCGTGGCGTGGATGATTGGCTG
GGACCTGCTGCTCGAGTACGGGCTGGCCACGTCGGCGGTGTCAGTAGGGTGGTCCGGCTACTTCCAGTCGCTGATCGCCG
GGTTCGGCATCCATCTGCCGACCGTGCTGACTGCCGCGCCGGGCGCGGTGCCCGGTGAACACACGCTGTTCAACCTGCCC
GCCTGCCTGATCATGCTGGCGATCACCTGGATCGTTTCATACGGCGTCAAGGAGTCGGCGCGACTCAACAACGTGATGGT
GGCGATCAAGATCGGCGTCGTGCTGCTGTTCATCGCCGTCGGCGTCTGGCACGTGAAGCCCGCCAACTGGCAGCCGTTCG
CGCCGTTCGGCATGACCGGCGTCTTCAACGCCGCCGCGCTCGTCTTCTTCGCGTTCATCGGGTTCGATGCGGTGACGTCG
GCCGCCGAGGAAGTGCGCAACCCGCGCCGTGACCTGCCGATCGGCATCATCGGCTCGCTGGCGGTTTGCACCATCCTTTA
CGTGACCGTGGCAGCCATCATGACCGGCATCGTGCCATTCATGAAGTTCGAGGGCGTTGACCATCCGGTGTCGCTGGCGC
TGCAATACGCGGGGCAGAACTGGGTGGCCGGGTTTGTTGATCTGGGCGCCATCCTCGGCATGACCACCGTGATTCTGGTG
ATGACCTACGGGCAGACGCGGATCATCTTCGCCATGTCGCGCGACGGGTTGCTGCCGGAAGCGTTATCGACGGTGCACCC
GGTTCATGCAACGCCGTACACGGCCACGTGGACCGTCGGCATCGTGTTCGCGGCGATCGCCGCCTTCGTGCCGCTGAACG
TACTGGCCGAACTGATCAACATCGGCACGCTGGCCGCGTTCACGCTGATCTCGATCGCGATCCTTGTGTTGCGCCGCACG
CGCCCAGATTTGCGGCGCGGCTTCCGCTGCCCGGGCGTGCCCGTGGTGCCGCTGCTGGCCGTTGGCTTCTGCCTGTTCCT
GATGGCCCATCTGCAGGCGCTGACCTGGATTGCATTCCTGTGCTGGATCGGGCTGGGTCTGATCATTTACTTCGCTTACT
CGCGCCGCAACGCGGTGCTGCACAACCACGGCGGCGACGCCGAGGGCTGA

Upstream 100 bases:

>100_bases
TCGCTGGCGCCGCTGCCGTTCAAAAGATGCGCAGCCCAGACCGCCGGCGGATTCCGCACAACCTATAGTCCTTACACGGA
CTTTCTGCCGGAGCCGCGCC

Downstream 100 bases:

>100_bases
TCAGCGGCTGCCGGCGTCCTCGAGGAACGCGCGTGCGCGGGGATCGCTCGCGTAGGCCGAGTTGATGCGCACCCACGCCG
TGGTCTCGCCGCCGGGGCGA

Product: putative amino-acid transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSLFRTKNIDAMLEVSEHDGLRKVLGAVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTVSFVIAAMACGFAALCYAEFA
SAIPVSGSIYTYSYATLGEIVAWMIGWDLLLEYGLATSAVSVGWSGYFQSLIAGFGIHLPTVLTAAPGAVPGEHTLFNLP
ACLIMLAITWIVSYGVKESARLNNVMVAIKIGVVLLFIAVGVWHVKPANWQPFAPFGMTGVFNAAALVFFAFIGFDAVTS
AAEEVRNPRRDLPIGIIGSLAVCTILYVTVAAIMTGIVPFMKFEGVDHPVSLALQYAGQNWVAGFVDLGAILGMTTVILV
MTYGQTRIIFAMSRDGLLPEALSTVHPVHATPYTATWTVGIVFAAIAAFVPLNVLAELINIGTLAAFTLISIAILVLRRT
RPDLRRGFRCPGVPVVPLLAVGFCLFLMAHLQALTWIAFLCWIGLGLIIYFAYSRRNAVLHNHGGDAEG

Sequences:

>Translated_469_residues
MSLFRTKNIDAMLEVSEHDGLRKVLGAVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTVSFVIAAMACGFAALCYAEFA
SAIPVSGSIYTYSYATLGEIVAWMIGWDLLLEYGLATSAVSVGWSGYFQSLIAGFGIHLPTVLTAAPGAVPGEHTLFNLP
ACLIMLAITWIVSYGVKESARLNNVMVAIKIGVVLLFIAVGVWHVKPANWQPFAPFGMTGVFNAAALVFFAFIGFDAVTS
AAEEVRNPRRDLPIGIIGSLAVCTILYVTVAAIMTGIVPFMKFEGVDHPVSLALQYAGQNWVAGFVDLGAILGMTTVILV
MTYGQTRIIFAMSRDGLLPEALSTVHPVHATPYTATWTVGIVFAAIAAFVPLNVLAELINIGTLAAFTLISIAILVLRRT
RPDLRRGFRCPGVPVVPLLAVGFCLFLMAHLQALTWIAFLCWIGLGLIIYFAYSRRNAVLHNHGGDAEG
>Mature_468_residues
SLFRTKNIDAMLEVSEHDGLRKVLGAVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTVSFVIAAMACGFAALCYAEFAS
AIPVSGSIYTYSYATLGEIVAWMIGWDLLLEYGLATSAVSVGWSGYFQSLIAGFGIHLPTVLTAAPGAVPGEHTLFNLPA
CLIMLAITWIVSYGVKESARLNNVMVAIKIGVVLLFIAVGVWHVKPANWQPFAPFGMTGVFNAAALVFFAFIGFDAVTSA
AEEVRNPRRDLPIGIIGSLAVCTILYVTVAAIMTGIVPFMKFEGVDHPVSLALQYAGQNWVAGFVDLGAILGMTTVILVM
TYGQTRIIFAMSRDGLLPEALSTVHPVHATPYTATWTVGIVFAAIAAFVPLNVLAELINIGTLAAFTLISIAILVLRRTR
PDLRRGFRCPGVPVVPLLAVGFCLFLMAHLQALTWIAFLCWIGLGLIIYFAYSRRNAVLHNHGGDAEG

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=416, Percent_Identity=34.8557692307692, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI258614003, Length=416, Percent_Identity=34.8557692307692, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI258645169, Length=416, Percent_Identity=35.3365384615385, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=34.6330275229358, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI181337167, Length=418, Percent_Identity=37.0813397129187, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI110347453, Length=409, Percent_Identity=37.1638141809291, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=32.8703703703704, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=32.8703703703704, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI186910308, Length=416, Percent_Identity=25.2403846153846, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910306, Length=416, Percent_Identity=25.2403846153846, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910304, Length=416, Percent_Identity=25.2403846153846, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI187423910, Length=478, Percent_Identity=25.9414225941423, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI7657591, Length=478, Percent_Identity=25.9414225941423, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI115648063, Length=417, Percent_Identity=24.220623501199, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI115648022, Length=417, Percent_Identity=24.220623501199, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI71979932, Length=448, Percent_Identity=27.9017857142857, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7657683, Length=410, Percent_Identity=26.3414634146341, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI9790235, Length=300, Percent_Identity=27, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI33286428, Length=425, Percent_Identity=25.1764705882353, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87081869, Length=486, Percent_Identity=24.2798353909465, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082023, Length=464, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786694, Length=460, Percent_Identity=25.2173913043478, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786302, Length=436, Percent_Identity=22.9357798165138, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081915, Length=424, Percent_Identity=23.1132075471698, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788480, Length=455, Percent_Identity=24.3956043956044, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082250, Length=426, Percent_Identity=24.6478873239437, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081708, Length=488, Percent_Identity=23.9754098360656, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789017, Length=450, Percent_Identity=23.1111111111111, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786602, Length=440, Percent_Identity=20.4545454545455, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1786789, Length=340, Percent_Identity=21.4705882352941, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=34.9514563106796, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17533459, Length=409, Percent_Identity=31.7848410757946, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17531343, Length=405, Percent_Identity=31.6049382716049, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17568033, Length=415, Percent_Identity=26.5060240963855, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540018, Length=415, Percent_Identity=25.5421686746988, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71982612, Length=420, Percent_Identity=23.3333333333333, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17537453, Length=364, Percent_Identity=23.3516483516484, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=420, Percent_Identity=23.3333333333333, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=35.0710900473934, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=35.0710900473934, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24668806, Length=423, Percent_Identity=35.2245862884161, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21356285, Length=423, Percent_Identity=35.2245862884161, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24668802, Length=423, Percent_Identity=35.2245862884161, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24667468, Length=421, Percent_Identity=34.4418052256532, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI161077963, Length=410, Percent_Identity=35.3658536585366, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=32.9297820823245, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=32.9297820823245, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=32.8502415458937, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=32.8502415458937, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI21357367, Length=428, Percent_Identity=26.6355140186916, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651635, Length=409, Percent_Identity=26.161369193154, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651633, Length=409, Percent_Identity=26.161369193154, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221331183, Length=427, Percent_Identity=26.6978922716628, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17647653, Length=427, Percent_Identity=26.6978922716628, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24664379, Length=427, Percent_Identity=26.6978922716628, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45550968, Length=423, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19921172, Length=423, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24641995, Length=418, Percent_Identity=25.1196172248804, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641993, Length=418, Percent_Identity=25.1196172248804, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49859; Mature: 49727

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRTKNIDAMLEVSEHDGLRKVLGAVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTV
CCCCCCCCCHHEEEEHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHH
SFVIAAMACGFAALCYAEFASAIPVSGSIYTYSYATLGEIVAWMIGWDLLLEYGLATSAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGWSGYFQSLIAGFGIHLPTVLTAAPGAVPGEHTLFNLPACLIMLAITWIVSYGVKESA
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
RLNNVMVAIKIGVVLLFIAVGVWHVKPANWQPFAPFGMTGVFNAAALVFFAFIGFDAVTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAEEVRNPRRDLPIGIIGSLAVCTILYVTVAAIMTGIVPFMKFEGVDHPVSLALQYAGQN
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
WVAGFVDLGAILGMTTVILVMTYGQTRIIFAMSRDGLLPEALSTVHPVHATPYTATWTVG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHH
IVFAAIAAFVPLNVLAELINIGTLAAFTLISIAILVLRRTRPDLRRGFRCPGVPVVPLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHH
VGFCLFLMAHLQALTWIAFLCWIGLGLIIYFAYSRRNAVLHNHGGDAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
>Mature Secondary Structure 
SLFRTKNIDAMLEVSEHDGLRKVLGAVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTV
CCCCCCCCHHEEEEHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]