Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 94309083

GI number: 94309083

Start: 143182

End: 144117

Strand: Reverse

Name: nahR [H]

Synonym: Rmet_0138

Alternate gene names: 94309083

Gene position: 144117-143182 (Counterclockwise)

Preceding gene: 94309084

Following gene: 94309081

Centisome position: 3.67

GC content: 68.48

Gene sequence:

>936_bases
ATGAATAGCCTTCGTGGAATCGACCTCAACCTTCTGGTGGTGCTGGAAGCGCTGCTTGCGGAACGCCATATTTCGCGCGC
CGCACTGCGCCTGCAGCTCAGTCAACCCGCCGTGAGCCACTCGCTGGCGCGGCTGCGCCAGTTGCTCGACGATCCCCTGC
TGGTACGTGGCCAGGGCGGCCTGGTGCTGACCGCGCGCGCCCACGAACTGGCCGCGCCACTGGCCGAGGCGCTCGCGCAG
GTCCGCATCCTGCTGGGGCCCGGTGGCTTCCAGCCCGCCACGGCCCGGCGGACGTTCAAGCTGGCGATGTCCGACTATGG
TTCGCTGGTGGTGTTGCCGCGCCTGCTGCGCACGGTGCGCAAGGCCGCGCCCAATATTGACCTCACCGTCACGCAGGGCA
GTCTGGAAACGATGACCGCTCAGGTAGCGGATGGCCAGATCGACCTGGCATTCGGCGCCTTCGCATTCGAGCCGGAAGGC
GTGCGCACCGCGGTGCTGTTCGACGACGATTTTGCATGTGCCGTGGACGCCGCAACGGTTCGCGATACGGGCCGGCTAGA
TCACGTGGCCTATCTGGCGCGCTCGCACGTGCTGGTGACCGCAGCCACCGAGCGCGGGGACGCCATCGACGCGGCCGTGA
CCCGACTGGGCGGGCGACGCAAGATCGCCTGCACCGTGCCGCACTGGAGCGTGGCGCCCGGCCTGATCCTTGGCACCAAC
ATGGTCCTGACCACCGCGCGCCGCTCGCTGGAAGCGCTGGCAGACGACCGTCTGGCGATCTTCGAGGCGCCGTTCACGAT
CCCCGGCTTCGCGTTCTGCATGATCTGGCCGGCGAAGGCCGACGCGGACCCGGGACTGACCTGGCTACGCGAACGGGTAT
TGCAAGCGGTCGCGCCGGAAGCGGAAAGCTCCGACGCGATCAGCCTGCGCGGCTGA

Upstream 100 bases:

>100_bases
GCAGCGGCAGGACGACGTCCCCCAGGACGCCGTTGCTCCAGATTGAATTTTTAGAGCAGCGAATGCCCAAACACCCCAAG
TTCGGTTTAACATTCGCGGC

Downstream 100 bases:

>100_bases
CCACCCCGTCCGATGACCCCTGACGGGGTCCGGTGCCGACGCTCAACGTACCCGGATCAGCACCGGAAATCAGCGCATCG
CTGCTTCAGTGCTTGTGATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNSLRGIDLNLLVVLEALLAERHISRAALRLQLSQPAVSHSLARLRQLLDDPLLVRGQGGLVLTARAHELAAPLAEALAQ
VRILLGPGGFQPATARRTFKLAMSDYGSLVVLPRLLRTVRKAAPNIDLTVTQGSLETMTAQVADGQIDLAFGAFAFEPEG
VRTAVLFDDDFACAVDAATVRDTGRLDHVAYLARSHVLVTAATERGDAIDAAVTRLGGRRKIACTVPHWSVAPGLILGTN
MVLTTARRSLEALADDRLAIFEAPFTIPGFAFCMIWPAKADADPGLTWLRERVLQAVAPEAESSDAISLRG

Sequences:

>Translated_311_residues
MNSLRGIDLNLLVVLEALLAERHISRAALRLQLSQPAVSHSLARLRQLLDDPLLVRGQGGLVLTARAHELAAPLAEALAQ
VRILLGPGGFQPATARRTFKLAMSDYGSLVVLPRLLRTVRKAAPNIDLTVTQGSLETMTAQVADGQIDLAFGAFAFEPEG
VRTAVLFDDDFACAVDAATVRDTGRLDHVAYLARSHVLVTAATERGDAIDAAVTRLGGRRKIACTVPHWSVAPGLILGTN
MVLTTARRSLEALADDRLAIFEAPFTIPGFAFCMIWPAKADADPGLTWLRERVLQAVAPEAESSDAISLRG
>Mature_311_residues
MNSLRGIDLNLLVVLEALLAERHISRAALRLQLSQPAVSHSLARLRQLLDDPLLVRGQGGLVLTARAHELAAPLAEALAQ
VRILLGPGGFQPATARRTFKLAMSDYGSLVVLPRLLRTVRKAAPNIDLTVTQGSLETMTAQVADGQIDLAFGAFAFEPEG
VRTAVLFDDDFACAVDAATVRDTGRLDHVAYLARSHVLVTAATERGDAIDAAVTRLGGRRKIACTVPHWSVAPGLILGTN
MVLTTARRSLEALADDRLAIFEAPFTIPGFAFCMIWPAKADADPGLTWLRERVLQAVAPEAESSDAISLRG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=167, Percent_Identity=32.3353293413174, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=24.8344370860927, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081766, Length=168, Percent_Identity=29.7619047619048, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33307; Mature: 33307

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLRGIDLNLLVVLEALLAERHISRAALRLQLSQPAVSHSLARLRQLLDDPLLVRGQGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCEEEECCCC
LVLTARAHELAAPLAEALAQVRILLGPGGFQPATARRTFKLAMSDYGSLVVLPRLLRTVR
EEEEECHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHEEEEHHHCCCCCHHHHHHHHHHH
KAAPNIDLTVTQGSLETMTAQVADGQIDLAFGAFAFEPEGVRTAVLFDDDFACAVDAATV
HHCCCCEEEEECCCHHHHHHHHCCCEEEEEEEEEEECCCCCEEEEEECCCCEEEEECHHH
RDTGRLDHVAYLARSHVLVTAATERGDAIDAAVTRLGGRRKIACTVPHWSVAPGLILGTN
CCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEECCC
MVLTTARRSLEALADDRLAIFEAPFTIPGFAFCMIWPAKADADPGLTWLRERVLQAVAPE
HHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCC
AESSDAISLRG
CCCCCCEEECC
>Mature Secondary Structure
MNSLRGIDLNLLVVLEALLAERHISRAALRLQLSQPAVSHSLARLRQLLDDPLLVRGQGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCEEEECCCC
LVLTARAHELAAPLAEALAQVRILLGPGGFQPATARRTFKLAMSDYGSLVVLPRLLRTVR
EEEEECHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHEEEEHHHCCCCCHHHHHHHHHHH
KAAPNIDLTVTQGSLETMTAQVADGQIDLAFGAFAFEPEGVRTAVLFDDDFACAVDAATV
HHCCCCEEEEECCCHHHHHHHHCCCEEEEEEEEEEECCCCCEEEEEECCCCEEEEECHHH
RDTGRLDHVAYLARSHVLVTAATERGDAIDAAVTRLGGRRKIACTVPHWSVAPGLILGTN
CCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEECCC
MVLTTARRSLEALADDRLAIFEAPFTIPGFAFCMIWPAKADADPGLTWLRERVLQAVAPE
HHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCC
AESSDAISLRG
CCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]