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The map label for this gene is bioD [H]

Identifier: 94309061

GI number: 94309061

Start: 122902

End: 123666

Strand: Direct

Name: bioD [H]

Synonym: Rmet_0116

Alternate gene names: 94309061

Gene position: 122902-123666 (Clockwise)

Preceding gene: 94309060

Following gene: 335055478

Centisome position: 3.13

GC content: 67.97

Gene sequence:

>765_bases
ATGACCGGCATCGCCGACCGGCCAGAGCGCTTCGCCTGCTTCATCACCGGTACCGATACCGGCGTGGGCAAGACGCATGC
GACCGCCACGCTGCTGCACGCGCTGCATGGCGCGGGTTACAGCACGGTGGGCATGAAGCCTATCGCCGCGGGCGGAGAAT
GGCTCGACGACCAGTGGCAGAACGACGACGTCGATCAGCTTCGCGCGGCCGGCTCCGTGATCGTGCCGCAGGAAAAGATG
TGCCCGTTCTTCTTTCGCACGCCGGTATCGCCGCATCTGGCCGCCGCGCTCGAAGGCGCGCGCATTACGCCCGAGCCGAT
TCGCGATGCATTCGAATCGTTGCGTCAGCGCGCCGAGGCCGTGGTGGTCGAAGGTGTGGGTGGCTTCATCGTGCCGCTCG
ACATGGGCGCCGCGCGCTGGAACACGGCGGACCTGGCCGTAATGCTCGACCTGCCGGTGATCATGGTGGTCGGTATCCGC
CTGGGTTGCCTCAGTCACGCCATGCTGACCGCCGAAGCGATTCGCGCACGCGGCCTCAGGCTGGCTGGCTGGATCGCCAA
CCGTATCGACCCCGACATGCTGCTGCCAAGCGAGAACATCGTCACGCTGCAGGATGCGCTGGGCGCGCTTGACGCACCGC
TGCTGGGCGAACTGCCGTGGCAGGTCGCGCCCGCCGTGGCAGCCCAGTACCTCGACCTCGCGCCGCTGCTGTCGGCCGCG
CCGTCCGTTGTCCCCCATCACAGTGCCGCGACGCATCGCGCGTGA

Upstream 100 bases:

>100_bases
GGCTGCGCATCACGCTGTCGGCATCGCACTCTGCAGCCGACGTGGCGCGACTGCTGGAGACCATCGCGCGCGCCGCGCCC
CAACTGCACAAGGAGGCTGC

Downstream 100 bases:

>100_bases
AGTGGCCAAACCGAATCCACTACCGAACCCCATACCGATCATGACGCAACAAGCCAACCAGACCGTCGCCACCATTTCCG
CCGAAGCCCTGCGCCAGTCG

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTGIADRPERFACFITGTDTGVGKTHATATLLHALHGAGYSTVGMKPIAAGGEWLDDQWQNDDVDQLRAAGSVIVPQEKM
CPFFFRTPVSPHLAAALEGARITPEPIRDAFESLRQRAEAVVVEGVGGFIVPLDMGAARWNTADLAVMLDLPVIMVVGIR
LGCLSHAMLTAEAIRARGLRLAGWIANRIDPDMLLPSENIVTLQDALGALDAPLLGELPWQVAPAVAAQYLDLAPLLSAA
PSVVPHHSAATHRA

Sequences:

>Translated_254_residues
MTGIADRPERFACFITGTDTGVGKTHATATLLHALHGAGYSTVGMKPIAAGGEWLDDQWQNDDVDQLRAAGSVIVPQEKM
CPFFFRTPVSPHLAAALEGARITPEPIRDAFESLRQRAEAVVVEGVGGFIVPLDMGAARWNTADLAVMLDLPVIMVVGIR
LGCLSHAMLTAEAIRARGLRLAGWIANRIDPDMLLPSENIVTLQDALGALDAPLLGELPWQVAPAVAAQYLDLAPLLSAA
PSVVPHHSAATHRA
>Mature_253_residues
TGIADRPERFACFITGTDTGVGKTHATATLLHALHGAGYSTVGMKPIAAGGEWLDDQWQNDDVDQLRAAGSVIVPQEKMC
PFFFRTPVSPHLAAALEGARITPEPIRDAFESLRQRAEAVVVEGVGGFIVPLDMGAARWNTADLAVMLDLPVIMVVGIRL
GCLSHAMLTAEAIRARGLRLAGWIANRIDPDMLLPSENIVTLQDALGALDAPLLGELPWQVAPAVAAQYLDLAPLLSAAP
SVVPHHSAATHRA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=226, Percent_Identity=41.1504424778761, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87081944, Length=239, Percent_Identity=37.6569037656904, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26956; Mature: 26825

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIADRPERFACFITGTDTGVGKTHATATLLHALHGAGYSTVGMKPIAAGGEWLDDQWQ
CCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCC
NDDVDQLRAAGSVIVPQEKMCPFFFRTPVSPHLAAALEGARITPEPIRDAFESLRQRAEA
CCCHHHHHHCCCEECCHHHHCCHHEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHE
VVVEGVGGFIVPLDMGAARWNTADLAVMLDLPVIMVVGIRLGCLSHAMLTAEAIRARGLR
EEEECCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LAGWIANRIDPDMLLPSENIVTLQDALGALDAPLLGELPWQVAPAVAAQYLDLAPLLSAA
HHHHHHHCCCCCCCCCCCCEEEHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCC
PSVVPHHSAATHRA
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TGIADRPERFACFITGTDTGVGKTHATATLLHALHGAGYSTVGMKPIAAGGEWLDDQWQ
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCC
NDDVDQLRAAGSVIVPQEKMCPFFFRTPVSPHLAAALEGARITPEPIRDAFESLRQRAEA
CCCHHHHHHCCCEECCHHHHCCHHEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHE
VVVEGVGGFIVPLDMGAARWNTADLAVMLDLPVIMVVGIRLGCLSHAMLTAEAIRARGLR
EEEECCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LAGWIANRIDPDMLLPSENIVTLQDALGALDAPLLGELPWQVAPAVAAQYLDLAPLLSAA
HHHHHHHCCCCCCCCCCCCEEEHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCC
PSVVPHHSAATHRA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA