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The map label for this gene is argS

Identifier: 94309041

GI number: 94309041

Start: 102445

End: 104253

Strand: Direct

Name: argS

Synonym: Rmet_0096

Alternate gene names: 94309041

Gene position: 102445-104253 (Clockwise)

Preceding gene: 94309039

Following gene: 94309042

Centisome position: 2.61

GC content: 68.27

Gene sequence:

>1809_bases
ATGCTGCCTGTTCAGACCTCCCAACTTGCCGCCGCGTTCACGGATGCCGTGCGTGCGCTCGCCCCCGCCGATGCCAACCT
GCCCGCGGTGACATTCGAGCGACCCAAGGCAGCCGCCCACGGCGACCTGGCCTGCAACATCGCCATGCAGGTGGCCAAGT
CGCTCAAGACCAACCCGCGTGAGCTGGCGCAGAAGGTCGTCGACGCAGTCAAGGCCGATTCGCGCGCGACCGCGCTCGTG
GCCGCGCTCGAGATCGCCGGCCCGGGCTTCATCAACCTGCGCCTGAGCCCCGAGGCCCGCGCGGAAGTCCTGCGTGCCGT
GCTGGCGGATGGCGACCGCTACGGCGCGCGTCCGGTCGGCGAGCATGGCCAGGTGCTGGTGGAGTTCGTCTCCGCCAACC
CGACTGGCCCGCTGCACGTGGGCCACGGCCGCCAGGCCGCCCTGGGCGATGCGCTGGCGAACCTGCTGGCCTGGCAGGGC
TGGTCGGTCCATCGCGAGTTCTACTACAACGACGCCGGCGTGCAGATCCATACGCTGGCCATCTCGGTGCAGGCCCGGGC
GCGCGGCCTGAAGCCGGGTGACGCCGGCTGGCCCGAGTCCGCCTACAACGGTGACTACATCGCCGATATCGCAGCCGATT
TCCTGGCCGGCAAGACCGTGTCCGCCTCGGACGGCGAGCCGGTGACGGCCTCGGGCAACATCGAGGATCTGGAGTCGATC
CGCAAGTTCGCGGTGACCTACCTGCGCAACGAGCAGGACATCGACCTGCAGGCGTTTGGCGTCAAGTTCGACCGGTACTA
CCTGGAATCGTCGCTGTACAGCGATGGCCGCGTGGAAGCCGCCGTGCAATCGCTGATCGCCAAGGGCAAGACGTACGAGA
GCGAAGGCGCGCTGTGGCTGCGCACCACCGACGACGGCGACGACAAGGACCGCGTCATGAAGAAGGGCGACGGCACGTAC
ACGTACTTCGTGCCGGATGTGGCGTACCACACCACCAAGTGGGAACGCGGCTTCTCGAAGGTCATCAACGTGCAGGGCAG
CGACCACCACGGCACCATCGCCCGCGTGCGTGCCGGCCTGCAGGGCCTGGACATCGGCATTCCGCAGGGCTACCCCGACT
ACGTGCTGCACAAGATGGTCACCGTCATGAAGAACGGCGAGGAGGTGAAGATCTCCAAGCGCGCTGGTTCGTACGTGACC
GTGCGCGACCTGATCGAATGGAGCAACGGCGGCGAAGAGACGATCCGCGGTTGCCTGGAAGCAGGCGTGGCCGACTGGCC
CGCGCACTTCACGCGCGGCCGCGACGCGGTGCGCTTCTTCCTGCTGTCGCGCAAGGCCGACACCGAGTTCGTGTTCGACG
TGGACCTGGCGCTGAAGCAGAACGACGAGAACCCGGTGTACTACGTCCAGTACGCTCACGCCCGCATCTGCTCGATTTTC
GAGGCATGGGGCGGCGCGGACTGGGAAGCGCGGCTGGGCGAGCTGGCCAGCGTGGACCTGGCCGCCGTGACGGCTGCTGA
CGTGAGCCCGCAGGCGATCGCGCTGGGCCGCCGTCTGGCCGAGTTCCCCGACATGCTGGCCGCGGCCTCCAGCGAACTGG
CCCCGCACGCGGTGGCCTTCTACCTGCGCGACCTGGCTGGCGATTTCCACGCGTTCTACAACGCCGACCGCGTCCTGGTG
GACGACGAGACGGTCAAGCGCGCGCGGCTGGCACTGCTGGCTGCCACGCGCCAGGTGCTCAAGAACGGCCTGGCGGTGAT
CGGTGTTTCGGCACCGCAGCGCATGGACCGCGAAGCGGCTCCGGCCTGA

Upstream 100 bases:

>100_bases
AAAATTCCGCGTTTCCCGATTTCCACTGCCGGTCACGCGGCGCGGCGTTCACTTGCCGACGCATGGCCGGAAGCACCCCA
GCCTCAGGGCCCAGATATCC

Downstream 100 bases:

>100_bases
TCGTGGTACGGGTGGTGGGTTGACGCACCACCCGCCAGCCCATGGCATCGGCGGCCGGCAGTCGACAATTTGCGACGAAT
CTGAAGCCGTGCGTCATGGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MLPVQTSQLAAAFTDAVRALAPADANLPAVTFERPKAAAHGDLACNIAMQVAKSLKTNPRELAQKVVDAVKADSRATALV
AALEIAGPGFINLRLSPEARAEVLRAVLADGDRYGARPVGEHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLAWQG
WSVHREFYYNDAGVQIHTLAISVQARARGLKPGDAGWPESAYNGDYIADIAADFLAGKTVSASDGEPVTASGNIEDLESI
RKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVEAAVQSLIAKGKTYESEGALWLRTTDDGDDKDRVMKKGDGTY
TYFVPDVAYHTTKWERGFSKVINVQGSDHHGTIARVRAGLQGLDIGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVT
VRDLIEWSNGGEETIRGCLEAGVADWPAHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
EAWGGADWEARLGELASVDLAAVTAADVSPQAIALGRRLAEFPDMLAAASSELAPHAVAFYLRDLAGDFHAFYNADRVLV
DDETVKRARLALLAATRQVLKNGLAVIGVSAPQRMDREAAPA

Sequences:

>Translated_602_residues
MLPVQTSQLAAAFTDAVRALAPADANLPAVTFERPKAAAHGDLACNIAMQVAKSLKTNPRELAQKVVDAVKADSRATALV
AALEIAGPGFINLRLSPEARAEVLRAVLADGDRYGARPVGEHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLAWQG
WSVHREFYYNDAGVQIHTLAISVQARARGLKPGDAGWPESAYNGDYIADIAADFLAGKTVSASDGEPVTASGNIEDLESI
RKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVEAAVQSLIAKGKTYESEGALWLRTTDDGDDKDRVMKKGDGTY
TYFVPDVAYHTTKWERGFSKVINVQGSDHHGTIARVRAGLQGLDIGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVT
VRDLIEWSNGGEETIRGCLEAGVADWPAHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
EAWGGADWEARLGELASVDLAAVTAADVSPQAIALGRRLAEFPDMLAAASSELAPHAVAFYLRDLAGDFHAFYNADRVLV
DDETVKRARLALLAATRQVLKNGLAVIGVSAPQRMDREAAPA
>Mature_602_residues
MLPVQTSQLAAAFTDAVRALAPADANLPAVTFERPKAAAHGDLACNIAMQVAKSLKTNPRELAQKVVDAVKADSRATALV
AALEIAGPGFINLRLSPEARAEVLRAVLADGDRYGARPVGEHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLAWQG
WSVHREFYYNDAGVQIHTLAISVQARARGLKPGDAGWPESAYNGDYIADIAADFLAGKTVSASDGEPVTASGNIEDLESI
RKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVEAAVQSLIAKGKTYESEGALWLRTTDDGDDKDRVMKKGDGTY
TYFVPDVAYHTTKWERGFSKVINVQGSDHHGTIARVRAGLQGLDIGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVT
VRDLIEWSNGGEETIRGCLEAGVADWPAHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
EAWGGADWEARLGELASVDLAAVTAADVSPQAIALGRRLAEFPDMLAAASSELAPHAVAFYLRDLAGDFHAFYNADRVLV
DDETVKRARLALLAATRQVLKNGLAVIGVSAPQRMDREAAPA

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=623, Percent_Identity=24.2375601926164, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1788184, Length=597, Percent_Identity=28.4757118927973, Blast_Score=158, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71985061, Length=631, Percent_Identity=24.7226624405705, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71985068, Length=595, Percent_Identity=24.5378151260504, Blast_Score=100, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=623, Percent_Identity=24.7191011235955, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI18859963, Length=631, Percent_Identity=23.6133122028526, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_RALME (Q1LS94)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_582251.1
- ProteinModelPortal:   Q1LS94
- STRING:   Q1LS94
- GeneID:   4036880
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_0096
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   ETIRGCL
- PhylomeDB:   Q1LS94
- ProtClustDB:   PRK01611
- BioCyc:   RMET266264:RMET_0096-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65232; Mature: 65232

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVQTSQLAAAFTDAVRALAPADANLPAVTFERPKAAAHGDLACNIAMQVAKSLKTNPR
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHH
ELAQKVVDAVKADSRATALVAALEIAGPGFINLRLSPEARAEVLRAVLADGDRYGARPVG
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCC
EHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLAWQGWSVHREFYYNDAGVQIHTLA
CCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEE
ISVQARARGLKPGDAGWPESAYNGDYIADIAADFLAGKTVSASDGEPVTASGNIEDLESI
EEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHH
RKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVEAAVQSLIAKGKTYESEGALWL
HHHHHHHHCCCCCCCEEEECEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEE
RTTDDGDDKDRVMKKGDGTYTYFVPDVAYHTTKWERGFSKVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHCCCCEEEEEECCHHHHCCHHHHHHHHHEECCCCCCCCHHHHHHHCC
QGLDIGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVTVRDLIEWSNGGEETIRGCLE
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHH
AGVADWPAHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
CCCCCCCHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHHHHHHHH
EAWGGADWEARLGELASVDLAAVTAADVSPQAIALGRRLAEFPDMLAAASSELAPHAVAF
HHHCCCCHHHHHHHHHCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YLRDLAGDFHAFYNADRVLVDDETVKRARLALLAATRQVLKNGLAVIGVSAPQRMDREAA
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCC
PA
CC
>Mature Secondary Structure
MLPVQTSQLAAAFTDAVRALAPADANLPAVTFERPKAAAHGDLACNIAMQVAKSLKTNPR
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHH
ELAQKVVDAVKADSRATALVAALEIAGPGFINLRLSPEARAEVLRAVLADGDRYGARPVG
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCC
EHGQVLVEFVSANPTGPLHVGHGRQAALGDALANLLAWQGWSVHREFYYNDAGVQIHTLA
CCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEE
ISVQARARGLKPGDAGWPESAYNGDYIADIAADFLAGKTVSASDGEPVTASGNIEDLESI
EEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHH
RKFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYSDGRVEAAVQSLIAKGKTYESEGALWL
HHHHHHHHCCCCCCCEEEECEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEE
RTTDDGDDKDRVMKKGDGTYTYFVPDVAYHTTKWERGFSKVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHCCCCEEEEEECCHHHHCCHHHHHHHHHEECCCCCCCCHHHHHHHCC
QGLDIGIPQGYPDYVLHKMVTVMKNGEEVKISKRAGSYVTVRDLIEWSNGGEETIRGCLE
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHH
AGVADWPAHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
CCCCCCCHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHHHHHHHH
EAWGGADWEARLGELASVDLAAVTAADVSPQAIALGRRLAEFPDMLAAASSELAPHAVAF
HHHCCCCHHHHHHHHHCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YLRDLAGDFHAFYNADRVLVDDETVKRARLALLAATRQVLKNGLAVIGVSAPQRMDREAA
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA