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The map label for this gene is mrdB [H]

Identifier: 94309000

GI number: 94309000

Start: 63631

End: 64773

Strand: Direct

Name: mrdB [H]

Synonym: Rmet_0055

Alternate gene names: 94309000

Gene position: 63631-64773 (Clockwise)

Preceding gene: 94308999

Following gene: 94309001

Centisome position: 1.62

GC content: 61.33

Gene sequence:

>1143_bases
ATGGACCGACGCCGCGTCGTATCGATCATCAAGTCTGCCCTGACCGGCTTCGACAAGCCGCTGGCCTTGATCGTCTTTCT
GCTGTTCGCCACCGGCATCGTTGCGCTGTACTCGGCCGCGATCGACATGCCGGGCCGGGTCGAGGACCAGCTGCGCAATA
TCCTGCTGTCGTACGTGGTGATGCTGGTGATCGCCTACATGCCGACCCAGCTGTTGATGCGGATTGCCGTGCCGCTCTAC
ACCGTGGGGGTAGCGCTGCTGATTGCCGTGGCGATGTTCGGCCTGATCCGCAAGGGCGCGCGGCGCTGGCTGAACGTGGG
GATGGTGATTCAGCCCTCCGAGATCATGAAGATCGCGATGCCACTGATGCTGGCGTGGTACTTCCAGAAACGCGAGGGGG
TGATCAAATGGTTCGACTTCGTCGTGGCACTGATCATGCTCGGTATTCCGGTCGGCCTGATCGCCAAGCAGCCTGACCTG
GGCACTGCGTTGCTGGTGCTGGCCGCCGGCATCTACGTGATCTACTTCGCGGGCTTGACGTGGAAGATCATCCTGCCGAT
TCTCGGTGCGGGCGTGGTCGTGATCACGCTGATCGTGACTTACCAGAACCAGATCTGTGCGCCGGGCGTGAACTGGCCGA
TCCTGCACGACTACCAGCAGCACCGTGTCTGCACGCTGCTCGACCCGACCACTGATCCGCTCGGCAAGGGCTTTCACACG
ATCCAGTCGATCATCGCGATTGGCTCGGGCGGGGTGACCGGCAAGGGCTGGCTCAAGGGCACACAGACGCACCTCGAATT
CATCCCCGAGAAGCACACCGACTTCATCTTCGCCGTGTTCTCCGAGGAGTTCGGGCTGATCGGTAATGCGGTGCTACTGG
TCCTGTACCTGCTGCTGATCTTCCGCGGGCTCTATATTGCGGCGAACGCGCCAACGCTGTTCTCGCGTCTGCTGGCCGGC
TCCATCACGCTGATCTTCTTCACCTACGCCTTCGTGAACATGGGCATGGTGAGCGGGATCCTGCCGGTGGTGGGCGTGCC
GCTGCCGCTGATGAGCTACGGGGGAACCGCGCTGGTGACGCTGGGAATGGGCATCGGCATTCTGATGAGCATTTCCAGGC
AGAAAAGGTTGATACAAACGTAG

Upstream 100 bases:

>100_bases
CCGAAGACGCAGCCCGCCCGGCCAAAGCCCGCCAATGTCGCGGGCCCGGCCTCGGGCTCGTCGGCCCGCAACAACGTTTC
AGAGTAATAAGGAGACGCGC

Downstream 100 bases:

>100_bases
TGGATGGCGTCTTTGCTACACTGCCATCCAAAATTTGTTCCGGTGGAAGCCCATGAACGCTCAAGACGTTGCCGCTTACC
TGCAGAGCCATCCGCAGTTT

Product: cell wall shape-determining protein MrdB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDRRRVVSIIKSALTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVVMLVIAYMPTQLLMRIAVPLY
TVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKIAMPLMLAWYFQKREGVIKWFDFVVALIMLGIPVGLIAKQPDL
GTALLVLAAGIYVIYFAGLTWKIILPILGAGVVVITLIVTYQNQICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
IQSIIAIGSGGVTGKGWLKGTQTHLEFIPEKHTDFIFAVFSEEFGLIGNAVLLVLYLLLIFRGLYIAANAPTLFSRLLAG
SITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVTLGMGIGILMSISRQKRLIQT

Sequences:

>Translated_380_residues
MDRRRVVSIIKSALTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVVMLVIAYMPTQLLMRIAVPLY
TVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKIAMPLMLAWYFQKREGVIKWFDFVVALIMLGIPVGLIAKQPDL
GTALLVLAAGIYVIYFAGLTWKIILPILGAGVVVITLIVTYQNQICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
IQSIIAIGSGGVTGKGWLKGTQTHLEFIPEKHTDFIFAVFSEEFGLIGNAVLLVLYLLLIFRGLYIAANAPTLFSRLLAG
SITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVTLGMGIGILMSISRQKRLIQT
>Mature_380_residues
MDRRRVVSIIKSALTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVVMLVIAYMPTQLLMRIAVPLY
TVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKIAMPLMLAWYFQKREGVIKWFDFVVALIMLGIPVGLIAKQPDL
GTALLVLAAGIYVIYFAGLTWKIILPILGAGVVVITLIVTYQNQICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
IQSIIAIGSGGVTGKGWLKGTQTHLEFIPEKHTDFIFAVFSEEFGLIGNAVLLVLYLLLIFRGLYIAANAPTLFSRLLAG
SITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVTLGMGIGILMSISRQKRLIQT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=346, Percent_Identity=49.1329479768786, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1786277, Length=380, Percent_Identity=28.6842105263158, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41567; Mature: 41567

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRRVVSIIKSALTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MLVIAYMPTQLLMRIAVPLYTVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKIAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHH
PLMLAWYFQKREGVIKWFDFVVALIMLGIPVGLIAKQPDLGTALLVLAAGIYVIYFAGLT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
WKIILPILGAGVVVITLIVTYQNQICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCHHHH
IQSIIAIGSGGVTGKGWLKGTQTHLEFIPEKHTDFIFAVFSEEFGLIGNAVLLVLYLLLI
HHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
FRGLYIAANAPTLFSRLLAGSITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHH
LGMGIGILMSISRQKRLIQT
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRRRVVSIIKSALTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MLVIAYMPTQLLMRIAVPLYTVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKIAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHH
PLMLAWYFQKREGVIKWFDFVVALIMLGIPVGLIAKQPDLGTALLVLAAGIYVIYFAGLT
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
WKIILPILGAGVVVITLIVTYQNQICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCHHHH
IQSIIAIGSGGVTGKGWLKGTQTHLEFIPEKHTDFIFAVFSEEFGLIGNAVLLVLYLLLI
HHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
FRGLYIAANAPTLFSRLLAGSITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHH
LGMGIGILMSISRQKRLIQT
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]