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The map label for this gene is mreB [H]

Identifier: 94308996

GI number: 94308996

Start: 58487

End: 59530

Strand: Direct

Name: mreB [H]

Synonym: Rmet_0051

Alternate gene names: 94308996

Gene position: 58487-59530 (Clockwise)

Preceding gene: 94308990

Following gene: 94308997

Centisome position: 1.49

GC content: 64.27

Gene sequence:

>1044_bases
ATGTTCGGATTTCTCCGCAGCTATTTCTCCAACGACCTGGCCATCGACCTGGGCACCGCCAACACCCTGATTTACATGCG
CGACAAGGGCATCGTCCTGGACGAACCGTCGGTCGTGGCTATCCGTCAGGAAGGTGGCCCCAACGCCAAGAAGACGATTA
CCGCGGTGGGCAAGGAAGCCAAGCAGATGCTGGGCAAGGTCCCGGGCAACATCGAGGCCATCCGCCCGATGAAGGACGGC
GTCATTGCCGACTTCACCGTGACCGAGCAGATGCTCAAGCAGTTCATCAAGATGGTGCACGACTCGAAGCTGCTGCGTCC
GAGCCCGCGCATCATCATCTGCGTGCCGTGCGGTTCCACCCAGGTGGAACGCCGCGCCATCCGTGAATCGGCCCTGGGCG
CCGGCGCCAGCCAGGTGTACCTGATCGAGGAGCCGATGTCGGCGGCGATCGGCGCGGGCTTGCCCGTGTCGGAGCCGTCG
GGCTCGATGGTCGTCGATATCGGCGGCGGTACCACCGAGGTGGGCATCATCTCGCTGGGCGGCATGGTCTACAAGGGTTC
GGTGCGCGTGGGCGGCGACAAGTTCGACGAGGCGATCGTCAACTACATCCGCCGCAACTACGGCATGCTGATCGGCGAGC
AGACCGCCGAAGCGATCAAGAAGGAAATCGGCTCGGCCTTCCCGGGTTCGGAAGTCCGCGAAATGGAAGTCAAGGGCCGT
AACCTGTCCGAAGGCATTCCGCGCGCGTTCACGGTGTCGTCGAACGAAATCCTCGAAGCGCTGACCGATCCGCTGAACCA
GATCGTGTCGGCCGTGAAGATCGCGCTGGAACAGACCCCGCCGGAACTGGGCGCCGACATCGCCGAGCGCGGCATGATGC
TGACCGGCGGCGGCGCGCTGCTGCGTGATCTGGACCGTCTGCTGGCCGAGGAAACCGGCCTGCCGGTGCTGGTGGCCGAA
GACCCGCTGACCTGCGTGGTACGCGGCTCCGGCATGGCGCTGGAGCGTATGGACAAGCTCGGCAGCATCTTCTCGTACGA
GTAA

Upstream 100 bases:

>100_bases
GGAGCCGTGAACCATCACCCTTGCAAACGATTCGTGGCCGGGCCGCAGGCGGCGCCGGCCGCTTCGCATACCCGCGAAAC
AACAGAAGACAGGATTCCTG

Downstream 100 bases:

>100_bases
TGCAACCGGACCCGGCAACGTGGTGAGTCGCGTCGCCGGGCCCTCCCCCATCTTGAACGTTTTCTCCGCCAGCCCGACCC
GCCCCGTCCCGCAAGGGACG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFGFLRSYFSNDLAIDLGTANTLIYMRDKGIVLDEPSVVAIRQEGGPNAKKTITAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMSAAIGAGLPVSEPS
GSMVVDIGGGTTEVGIISLGGMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
NLSEGIPRAFTVSSNEILEALTDPLNQIVSAVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE

Sequences:

>Translated_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYMRDKGIVLDEPSVVAIRQEGGPNAKKTITAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMSAAIGAGLPVSEPS
GSMVVDIGGGTTEVGIISLGGMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
NLSEGIPRAFTVSSNEILEALTDPLNQIVSAVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE
>Mature_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYMRDKGIVLDEPSVVAIRQEGGPNAKKTITAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMSAAIGAGLPVSEPS
GSMVVDIGGGTTEVGIISLGGMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
NLSEGIPRAFTVSSNEILEALTDPLNQIVSAVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=350, Percent_Identity=72, Blast_Score=509, Evalue=1e-146,
Organism=Escherichia coli, GI1788875, Length=247, Percent_Identity=26.7206477732794, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323401, Length=264, Percent_Identity=26.1363636363636, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37092; Mature: 37092

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYMRDKGIVLDEPSVVAIRQEGGPNAKKTITAVGKEA
CCHHHHHHCCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
QVERRAIRESALGAGASQVYLIEEPMSAAIGAGLPVSEPSGSMVVDIGGGTTEVGIISLG
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCHHHHHHCCC
NLSEGIPRAFTVSSNEILEALTDPLNQIVSAVKIALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKLGSIFSYE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYMRDKGIVLDEPSVVAIRQEGGPNAKKTITAVGKEA
CCHHHHHHCCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
QVERRAIRESALGAGASQVYLIEEPMSAAIGAGLPVSEPSGSMVVDIGGGTTEVGIISLG
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCHHHHHHCCC
NLSEGIPRAFTVSSNEILEALTDPLNQIVSAVKIALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKLGSIFSYE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]