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The map label for this gene is tcrA [H]

Identifier: 94308972

GI number: 94308972

Start: 31311

End: 32078

Strand: Reverse

Name: tcrA [H]

Synonym: Rmet_0027

Alternate gene names: 94308972

Gene position: 32078-31311 (Counterclockwise)

Preceding gene: 335055475

Following gene: 94308969

Centisome position: 0.82

GC content: 67.19

Gene sequence:

>768_bases
TTGAGAATCGCCGCGCTCGAAGACGACCCCGCCCGCGCCATCGTGCTGGAGCGAGCGTTGCATCCCGGCGGACACACGCT
TGCGCGATTTCGCAGCAGCCAGCCGATGATCGAGGCCATGCGTCGTGAGCCGTTCGATCTGCTGCTGCTGGACCGGGACG
TGGCCGGTACCAACGCCGATGATCTGCTCGATTGGGTGCGGCGCACACTGGGACACGGGATGCCGGTGATGATGCTGGGC
CAGAGCGATGCGGAGGAAGTGGTCGTGGGCTGCCTCGCGGCTGGCGCGGATGCGTACGTGCCACAGCCCGCGCGATGCGA
TGAACTTCGGGCCCGCATCGAGGCATTGACCCGGCGGGCAGCGGTGCCCGGCATGACGGTTGCCACCGTGCCGCCCGGCG
CGCTAGGGGACACCTCCGATCAACTCGTCTGCGGCGTGTTCCGCTTTGCGGTAGCGGAGCACCGCGTGTGGGTCAACAGC
ATGACCGTGGCCCTGTCGCCCAAGGAATACGCGCTGGCGCTGCTGCTGTTCCGCAACCTTGGCGCGCTGGTGACGCGCCG
CGCGATGATCGAGCACGTTTGGCCTGCCACGGGTATCAAGGAGCAGGCGCGCACCATCGACAGCCACCTGTCACGGGTAC
GCACCAAACTCGCGCTCTGGCCGTTCAACGGCATCATGCTGCGTTCGGTCTATCGGCTCGGGAGCCGCCTGGACCCGATA
GAAACAGCCGTCGCGACACGCGGCCGGCCGTCATTGGCTGCCCTATGA

Upstream 100 bases:

>100_bases
CTCATTTTCTGCATCGGCCACAAATGTTTACTTTCGTTTGGCGCGCGCATCGGCCTACCATGACCCGGAACATCTGACCT
GAACAGGAAGGAAACGCATC

Downstream 100 bases:

>100_bases
GGCGGATGAGGCGAATGTGGCAGATGTGGCCGCCGCCTTCGGCTGAGCGGAATCCATCTCAATCGATCTTGATGCCGGCT
TCCTTGACGATGCGCGCGTT

Product: response regulator, OmpR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRIAALEDDPARAIVLERALHPGGHTLARFRSSQPMIEAMRREPFDLLLLDRDVAGTNADDLLDWVRRTLGHGMPVMMLG
QSDAEEVVVGCLAAGADAYVPQPARCDELRARIEALTRRAAVPGMTVATVPPGALGDTSDQLVCGVFRFAVAEHRVWVNS
MTVALSPKEYALALLLFRNLGALVTRRAMIEHVWPATGIKEQARTIDSHLSRVRTKLALWPFNGIMLRSVYRLGSRLDPI
ETAVATRGRPSLAAL

Sequences:

>Translated_255_residues
MRIAALEDDPARAIVLERALHPGGHTLARFRSSQPMIEAMRREPFDLLLLDRDVAGTNADDLLDWVRRTLGHGMPVMMLG
QSDAEEVVVGCLAAGADAYVPQPARCDELRARIEALTRRAAVPGMTVATVPPGALGDTSDQLVCGVFRFAVAEHRVWVNS
MTVALSPKEYALALLLFRNLGALVTRRAMIEHVWPATGIKEQARTIDSHLSRVRTKLALWPFNGIMLRSVYRLGSRLDPI
ETAVATRGRPSLAAL
>Mature_255_residues
MRIAALEDDPARAIVLERALHPGGHTLARFRSSQPMIEAMRREPFDLLLLDRDVAGTNADDLLDWVRRTLGHGMPVMMLG
QSDAEEVVVGCLAAGADAYVPQPARCDELRARIEALTRRAAVPGMTVATVPPGALGDTSDQLVCGVFRFAVAEHRVWVNS
MTVALSPKEYALALLLFRNLGALVTRRAMIEHVWPATGIKEQARTIDSHLSRVRTKLALWPFNGIMLRSVYRLGSRLDPI
ETAVATRGRPSLAAL

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=24.5535714285714, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789402, Length=239, Percent_Identity=28.4518828451883, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=26.3829787234043, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786599, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=27.0042194092827, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=23.8532110091743, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27948; Mature: 27948

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAALEDDPARAIVLERALHPGGHTLARFRSSQPMIEAMRREPFDLLLLDRDVAGTNAD
CEECCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCHH
DLLDWVRRTLGHGMPVMMLGQSDAEEVVVGCLAAGADAYVPQPARCDELRARIEALTRRA
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AVPGMTVATVPPGALGDTSDQLVCGVFRFAVAEHRVWVNSMTVALSPKEYALALLLFRNL
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHH
GALVTRRAMIEHVWPATGIKEQARTIDSHLSRVRTKLALWPFNGIMLRSVYRLGSRLDPI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHH
ETAVATRGRPSLAAL
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MRIAALEDDPARAIVLERALHPGGHTLARFRSSQPMIEAMRREPFDLLLLDRDVAGTNAD
CEECCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCHH
DLLDWVRRTLGHGMPVMMLGQSDAEEVVVGCLAAGADAYVPQPARCDELRARIEALTRRA
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AVPGMTVATVPPGALGDTSDQLVCGVFRFAVAEHRVWVNSMTVALSPKEYALALLLFRNL
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHH
GALVTRRAMIEHVWPATGIKEQARTIDSHLSRVRTKLALWPFNGIMLRSVYRLGSRLDPI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHH
ETAVATRGRPSLAAL
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]