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The map label for this gene is apbE [H]

Identifier: 93007255

GI number: 93007255

Start: 3004539

End: 3005687

Strand: Direct

Name: apbE [H]

Synonym: Pcryo_2431

Alternate gene names: 93007255

Gene position: 3004539-3005687 (Clockwise)

Preceding gene: 93007254

Following gene: 93007256

Centisome position: 98.19

GC content: 46.21

Gene sequence:

>1149_bases
ATGAAAAACCCAAGCATGCAAAAATCAATACCACTCTCATTTTCTGTCAAATCGATGAATACCGCCCTACTACCTATTAT
TGCTATAAGCACTGCACTAGGGATGAGCGCTTGCCAGCAAAAGACCGATTATAATAATCTGAGCGGTGAGACCATGGGCA
CCAGCTATCATATTAGCTATCAGTTGCCTAAGGGCGCTGATGAAGCGACTATACAAGCAGCCATCGATAAGCGCCTGCAA
GATATCAATGACAGTATGTCCACTTATCAAGCGGACTCTACCATCTCTAAATTTAATCAATTAGGCAAAGATGAGCCTAT
TACCATCGATGAAGATTTTAATCATGTGTTGGTAGCTTCAAGACAAGTTTATGAGCTATCGGGTGGTGCCTTTGATCCTA
CAGTGATGCCATTGATAGACACTTGGGGCTTTGGTAGCACGATGACCGTTGAGCGTTTGCAAAGCCCACCGACGGCGCTT
GAGATTGCGCAAGCCAAAGCCTTGGTCGACTTTGAAAGTATCATTCAAAAAGATAAGACTATCTATAAAGCCAAAGATGG
CATTGGGCTTGATTTTTCAGCAGTGGCTAAAGGCTATGGTGTCGATGTCATCGCTGATGTGCTAAAAAACAATTATCAAA
TTCGCAATTATATGGTTGAGATTGGTGGTGAGGTGGCAACCTCTGGTGTCAGTGCGCAACAACAACCTTGGCAAATTGCG
ATTGATGCACCAATTGAAGGTAGTACCGTCAGCGAGCGTCAAACTATGGCAGTGATTCGCCAACCGATAAATAATGGCAA
CACGATGCATCTGGCGACCTCTGGCAACTATCGAAACTCAGTCGTCTTTGATGGTAAGCACTACAGTCATACCATTGACC
CGACCACAGGTGAGCCGATTGTAGGTGGTGCGCCATCGGTAACCGTCGCGGCAGACACCGTCGCGCTGGCTGATGCTTGG
GCAACCGCCTTAACTGCTATGCCTTACAAAAAAGCTTTGAGCGTCGCCAAGGAGCAAAACATAGCGGCATTGTTTGTCGT
GTTGGCAGATGGTGTGAGCATAGAAGCAGCTGCGGACAGCATTGATGATTGGCAAGTGGTGCAAACACCTGCTATGCAAG
CATTACGTGCTGATAAAAAGTCCAGCTAA

Upstream 100 bases:

>100_bases
GCGTTATGGGTGACAAGGGGTGTAAAATAGGCAACGCTTAGCTTATTTAATAGCTAACGCCTCATTTATCCCTTCGCTAT
ATCAAGTTGTGATGACTCAT

Downstream 100 bases:

>100_bases
ATCTAAAAACACTAATAGAAGCTAATTCGGTATCTTTCTGAAATTGTCTTACTAAGCTGAGAAGCTCAAACGGACAAGAT
GAATTTTTGCTATACTATTA

Product: ApbE-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKNPSMQKSIPLSFSVKSMNTALLPIIAISTALGMSACQQKTDYNNLSGETMGTSYHISYQLPKGADEATIQAAIDKRLQ
DINDSMSTYQADSTISKFNQLGKDEPITIDEDFNHVLVASRQVYELSGGAFDPTVMPLIDTWGFGSTMTVERLQSPPTAL
EIAQAKALVDFESIIQKDKTIYKAKDGIGLDFSAVAKGYGVDVIADVLKNNYQIRNYMVEIGGEVATSGVSAQQQPWQIA
IDAPIEGSTVSERQTMAVIRQPINNGNTMHLATSGNYRNSVVFDGKHYSHTIDPTTGEPIVGGAPSVTVAADTVALADAW
ATALTAMPYKKALSVAKEQNIAALFVVLADGVSIEAAADSIDDWQVVQTPAMQALRADKKSS

Sequences:

>Translated_382_residues
MKNPSMQKSIPLSFSVKSMNTALLPIIAISTALGMSACQQKTDYNNLSGETMGTSYHISYQLPKGADEATIQAAIDKRLQ
DINDSMSTYQADSTISKFNQLGKDEPITIDEDFNHVLVASRQVYELSGGAFDPTVMPLIDTWGFGSTMTVERLQSPPTAL
EIAQAKALVDFESIIQKDKTIYKAKDGIGLDFSAVAKGYGVDVIADVLKNNYQIRNYMVEIGGEVATSGVSAQQQPWQIA
IDAPIEGSTVSERQTMAVIRQPINNGNTMHLATSGNYRNSVVFDGKHYSHTIDPTTGEPIVGGAPSVTVAADTVALADAW
ATALTAMPYKKALSVAKEQNIAALFVVLADGVSIEAAADSIDDWQVVQTPAMQALRADKKSS
>Mature_382_residues
MKNPSMQKSIPLSFSVKSMNTALLPIIAISTALGMSACQQKTDYNNLSGETMGTSYHISYQLPKGADEATIQAAIDKRLQ
DINDSMSTYQADSTISKFNQLGKDEPITIDEDFNHVLVASRQVYELSGGAFDPTVMPLIDTWGFGSTMTVERLQSPPTAL
EIAQAKALVDFESIIQKDKTIYKAKDGIGLDFSAVAKGYGVDVIADVLKNNYQIRNYMVEIGGEVATSGVSAQQQPWQIA
IDAPIEGSTVSERQTMAVIRQPINNGNTMHLATSGNYRNSVVFDGKHYSHTIDPTTGEPIVGGAPSVTVAADTVALADAW
ATALTAMPYKKALSVAKEQNIAALFVVLADGVSIEAAADSIDDWQVVQTPAMQALRADKKSS

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=347, Percent_Identity=29.971181556196, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 40995; Mature: 40995

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNPSMQKSIPLSFSVKSMNTALLPIIAISTALGMSACQQKTDYNNLSGETMGTSYHISY
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
QLPKGADEATIQAAIDKRLQDINDSMSTYQADSTISKFNQLGKDEPITIDEDFNHVLVAS
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEC
RQVYELSGGAFDPTVMPLIDTWGFGSTMTVERLQSPPTALEIAQAKALVDFESIIQKDKT
CEEEEECCCCCCCCHHHHHHCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
IYKAKDGIGLDFSAVAKGYGVDVIADVLKNNYQIRNYMVEIGGEVATSGVSAQQQPWQIA
EEEECCCCCCCHHHHHCCCCHHHHHHHHHCCEEEEHHHHHHCCHHHHCCCCCCCCCEEEE
IDAPIEGSTVSERQTMAVIRQPINNGNTMHLATSGNYRNSVVFDGKHYSHTIDPTTGEPI
EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCCEECCCCCCCCC
VGGAPSVTVAADTVALADAWATALTAMPYKKALSVAKEQNIAALFVVLADGVSIEAAADS
CCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEECCCEEEECCCC
IDDWQVVQTPAMQALRADKKSS
CCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNPSMQKSIPLSFSVKSMNTALLPIIAISTALGMSACQQKTDYNNLSGETMGTSYHISY
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
QLPKGADEATIQAAIDKRLQDINDSMSTYQADSTISKFNQLGKDEPITIDEDFNHVLVAS
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEC
RQVYELSGGAFDPTVMPLIDTWGFGSTMTVERLQSPPTALEIAQAKALVDFESIIQKDKT
CEEEEECCCCCCCCHHHHHHCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
IYKAKDGIGLDFSAVAKGYGVDVIADVLKNNYQIRNYMVEIGGEVATSGVSAQQQPWQIA
EEEECCCCCCCHHHHHCCCCHHHHHHHHHCCEEEEHHHHHHCCHHHHCCCCCCCCCEEEE
IDAPIEGSTVSERQTMAVIRQPINNGNTMHLATSGNYRNSVVFDGKHYSHTIDPTTGEPI
EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCCEECCCCCCCCC
VGGAPSVTVAADTVALADAWATALTAMPYKKALSVAKEQNIAALFVVLADGVSIEAAADS
CCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEECCCEEEECCCC
IDDWQVVQTPAMQALRADKKSS
CCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]