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The map label for this gene is ribH [H]

Identifier: 93007216

GI number: 93007216

Start: 2941001

End: 2941522

Strand: Direct

Name: ribH [H]

Synonym: Pcryo_2392

Alternate gene names: 93007216

Gene position: 2941001-2941522 (Clockwise)

Preceding gene: 93007215

Following gene: 93007217

Centisome position: 96.12

GC content: 46.36

Gene sequence:

>522_bases
ATGTCAAATTTACAACAGCAACGCAATGACGTGACCCATATTGATGGCAATTTACATCAAAACGAGGACGTGCGTATCGG
TATCGTCGTCGGTCGTTTTAATGGTTTTGTCGTTGAGTCATTGGTTGATGGTGCGATTGATGCGTTGCTTCGTCATGGCG
TATTGGGCAGTAACATCACTGTGATTCGTGTGCCGGGTGCTTTCGAGTTGCCATTGGTTGCACAGCGTGCTGCTGAGTCT
GATCGCTTTGACGCTATCGTTGCTTTGGGTGCGATTATCCGTGGTAGCACGCCGCATTTTGACTTTGTCGCAAGCGAATC
TGCTAAAGGTTTAAGCAGTGTTGCCATTGACTATAATATTCCAGTAGCAAACGGCGTATTGACTACTGACAGCATCGAGC
AAGCGATTGAGCGTGCTGGTACTAAAGCTGGTAATAAAGGTTCAGAAGCAGCGATGGTTGTACTAGAAATGCTTGCTGTG
TTATCACAGTTAGACATTGATGATGGCAGCGAAGACGCTTAA

Upstream 100 bases:

>100_bases
AGCCAATTAAATAAGCGATTTGAACCTAGCAATATATTTAGATTCCTAATACTTAGATTCTTATACTTCTATTAATAGCC
TATTCGGCAAAGGATTTTTT

Downstream 100 bases:

>100_bases
TTGCACTCACTGTTAGCCGCATTTATGAGTATAAAATTATTATTTATTGTTTGAAACGGGGCTATGGTTATAACGATAGC
CCTTAGCACTTTACAATAGC

Product: riboflavin synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSNLQQQRNDVTHIDGNLHQNEDVRIGIVVGRFNGFVVESLVDGAIDALLRHGVLGSNITVIRVPGAFELPLVAQRAAES
DRFDAIVALGAIIRGSTPHFDFVASESAKGLSSVAIDYNIPVANGVLTTDSIEQAIERAGTKAGNKGSEAAMVVLEMLAV
LSQLDIDDGSEDA

Sequences:

>Translated_173_residues
MSNLQQQRNDVTHIDGNLHQNEDVRIGIVVGRFNGFVVESLVDGAIDALLRHGVLGSNITVIRVPGAFELPLVAQRAAES
DRFDAIVALGAIIRGSTPHFDFVASESAKGLSSVAIDYNIPVANGVLTTDSIEQAIERAGTKAGNKGSEAAMVVLEMLAV
LSQLDIDDGSEDA
>Mature_172_residues
SNLQQQRNDVTHIDGNLHQNEDVRIGIVVGRFNGFVVESLVDGAIDALLRHGVLGSNITVIRVPGAFELPLVAQRAAESD
RFDAIVALGAIIRGSTPHFDFVASESAKGLSSVAIDYNIPVANGVLTTDSIEQAIERAGTKAGNKGSEAAMVVLEMLAVL
SQLDIDDGSEDA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=144, Percent_Identity=58.3333333333333, Blast_Score=166, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324429, Length=150, Percent_Identity=30.6666666666667, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 18250; Mature: 18119

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLQQQRNDVTHIDGNLHQNEDVRIGIVVGRFNGFVVESLVDGAIDALLRHGVLGSNIT
CCCHHHHHCCCEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEE
VIRVPGAFELPLVAQRAAESDRFDAIVALGAIIRGSTPHFDFVASESAKGLSSVAIDYNI
EEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEECC
PVANGVLTTDSIEQAIERAGTKAGNKGSEAAMVVLEMLAVLSQLDIDDGSEDA
CCCCCEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNLQQQRNDVTHIDGNLHQNEDVRIGIVVGRFNGFVVESLVDGAIDALLRHGVLGSNIT
CCHHHHHCCCEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEE
VIRVPGAFELPLVAQRAAESDRFDAIVALGAIIRGSTPHFDFVASESAKGLSSVAIDYNI
EEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEECC
PVANGVLTTDSIEQAIERAGTKAGNKGSEAAMVVLEMLAVLSQLDIDDGSEDA
CCCCCEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA