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The map label for this gene is mraW [H]

Identifier: 93007204

GI number: 93007204

Start: 2926827

End: 2927978

Strand: Reverse

Name: mraW [H]

Synonym: Pcryo_2380

Alternate gene names: 93007204

Gene position: 2927978-2926827 (Counterclockwise)

Preceding gene: 93007208

Following gene: 93007203

Centisome position: 95.69

GC content: 46.53

Gene sequence:

>1152_bases
GTGTCCATATCGAATAGTAAGCCAAAAAATACGCCAAATGCTAATCACAATCCTTCTGACCCTGATCATTCTATGTCAGC
GGCGAGTCTGTTTTCTGAAGAAAGCACTTCTACTCAAAAACTTATGCAAGAGCCTAGTGAAGATCAAGCTACGTCTGACG
AATTGAGTTTTGTCCATGATGCGGTGCTATTGCAAGAAGCAGTCGCCGCAGTGTTGGGTGTCAAAGCGCTACCGAAGCAG
ACAGACGACGAAAGTCAAAATAGCTTGCAAGCAAGCGGTATCTATGTCGATGCTACCTTTGGTCGTGGTGGCCATAGTCG
CTTGCTATTAAGCCAGCTTGCCGATGATGCAACTTTGATTGTTTTTGATAAAGACCCAACAGCCATTAGCGTTGCTCGTG
AATTGGCAAATAGCGACAGTCGCGTAAAAGTGGTACATGATAGCTTTGCGACGTTAACAGACAGTCTTGCTGCAATGAGA
ATCACTCAAGTTGACGGCTTAATGGCAGACTTGGGTATCTCGTCACCACAAATTGATGATGGCAGTCGTGGTTTTAGTTT
TATGCGCGATGGCGCGGTCGATATGCGTATGGATACCAGCCGCGGGCAGTCAGTTGCTGAGTGGCTTGAGACGGTCGATG
ATGAAACCTTGGCCAATGTCCTTTATGAGTTTGGCGAAGAGCGTCACAGTCGCCGTATCGCTCGTGCCATTAAGCAAATG
GACAGTTACGACTCTACTTTAGCATTGGCTGAAGTGATAAAAGTTGCCCATCCAAACTGGCAACGCGGCAAGCATCCAGC
GACCCAGAGCTTTCAGGCGATGCGGATTTTTATTAACAACGAGCTTGGTGATGTCGATAACTTTTTAGAGCAAAGTATTC
CGATATTAAAGGTAGGCGGACAGCTAGCAGTGATTAGTTTTCACTCGTTAGAAGATCGCCGTATCAAGCAGTTTTTGCAG
CGTCATAGTAAAGGGCAATATCCAGAAGATGAGAATTTGCCGATGCCACCCAAGCGTCCACGTTACTTTAGTAAGCCAAA
ACGCGTCGGTCCTAGTAAAGCAGAGATAAGTCATAACCCACGCTCGCGTAGTGCATGGTTACGCATGGCAACACGTACTG
ATGCTGACTATGTAGCAGATATTCATCCATGA

Upstream 100 bases:

>100_bases
TATCCTTGCGATAATAATGTTAGGTAAGTCATAACTTGTTTATTTTCATCTGATTTTTTACTATTACTGGTCAATTTGAC
CATCATCTATTGAGTTGTTT

Downstream 100 bases:

>100_bases
ATGCCATTATTAACTTATGTGGTTTAAATATGACTGAATGTTTTAATGATTACGCGGCTGTTAAAAAGCTGTAAACATTA
TCTGCTAGGCTCAGCAGTTA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSISNSKPKNTPNANHNPSDPDHSMSAASLFSEESTSTQKLMQEPSEDQATSDELSFVHDAVLLQEAVAAVLGVKALPKQ
TDDESQNSLQASGIYVDATFGRGGHSRLLLSQLADDATLIVFDKDPTAISVARELANSDSRVKVVHDSFATLTDSLAAMR
ITQVDGLMADLGISSPQIDDGSRGFSFMRDGAVDMRMDTSRGQSVAEWLETVDDETLANVLYEFGEERHSRRIARAIKQM
DSYDSTLALAEVIKVAHPNWQRGKHPATQSFQAMRIFINNELGDVDNFLEQSIPILKVGGQLAVISFHSLEDRRIKQFLQ
RHSKGQYPEDENLPMPPKRPRYFSKPKRVGPSKAEISHNPRSRSAWLRMATRTDADYVADIHP

Sequences:

>Translated_383_residues
MSISNSKPKNTPNANHNPSDPDHSMSAASLFSEESTSTQKLMQEPSEDQATSDELSFVHDAVLLQEAVAAVLGVKALPKQ
TDDESQNSLQASGIYVDATFGRGGHSRLLLSQLADDATLIVFDKDPTAISVARELANSDSRVKVVHDSFATLTDSLAAMR
ITQVDGLMADLGISSPQIDDGSRGFSFMRDGAVDMRMDTSRGQSVAEWLETVDDETLANVLYEFGEERHSRRIARAIKQM
DSYDSTLALAEVIKVAHPNWQRGKHPATQSFQAMRIFINNELGDVDNFLEQSIPILKVGGQLAVISFHSLEDRRIKQFLQ
RHSKGQYPEDENLPMPPKRPRYFSKPKRVGPSKAEISHNPRSRSAWLRMATRTDADYVADIHP
>Mature_382_residues
SISNSKPKNTPNANHNPSDPDHSMSAASLFSEESTSTQKLMQEPSEDQATSDELSFVHDAVLLQEAVAAVLGVKALPKQT
DDESQNSLQASGIYVDATFGRGGHSRLLLSQLADDATLIVFDKDPTAISVARELANSDSRVKVVHDSFATLTDSLAAMRI
TQVDGLMADLGISSPQIDDGSRGFSFMRDGAVDMRMDTSRGQSVAEWLETVDDETLANVLYEFGEERHSRRIARAIKQMD
SYDSTLALAEVIKVAHPNWQRGKHPATQSFQAMRIFINNELGDVDNFLEQSIPILKVGGQLAVISFHSLEDRRIKQFLQR
HSKGQYPEDENLPMPPKRPRYFSKPKRVGPSKAEISHNPRSRSAWLRMATRTDADYVADIHP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=331, Percent_Identity=34.441087613293, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI165377202, Length=168, Percent_Identity=36.9047619047619, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1786270, Length=330, Percent_Identity=43.9393939393939, Blast_Score=272, Evalue=3e-74,
Organism=Drosophila melanogaster, GI62472493, Length=318, Percent_Identity=33.6477987421384, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28571637, Length=318, Percent_Identity=33.6477987421384, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 42420; Mature: 42289

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISNSKPKNTPNANHNPSDPDHSMSAASLFSEESTSTQKLMQEPSEDQATSDELSFVHD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHH
AVLLQEAVAAVLGVKALPKQTDDESQNSLQASGIYVDATFGRGGHSRLLLSQLADDATLI
HHHHHHHHHHHHHHHHCCCCCCCCHHHCEECCCEEEEEECCCCCHHHHHHHHHCCCCEEE
VFDKDPTAISVARELANSDSRVKVVHDSFATLTDSLAAMRITQVDGLMADLGISSPQIDD
EECCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSRGFSFMRDGAVDMRMDTSRGQSVAEWLETVDDETLANVLYEFGEERHSRRIARAIKQM
CCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSYDSTLALAEVIKVAHPNWQRGKHPATQSFQAMRIFINNELGDVDNFLEQSIPILKVGG
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHEECCCCCCHHHHHHHHCCCEEEECC
QLAVISFHSLEDRRIKQFLQRHSKGQYPEDENLPMPPKRPRYFSKPKRVGPSKAEISHNP
EEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
RSRSAWLRMATRTDADYVADIHP
CHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SISNSKPKNTPNANHNPSDPDHSMSAASLFSEESTSTQKLMQEPSEDQATSDELSFVHD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHH
AVLLQEAVAAVLGVKALPKQTDDESQNSLQASGIYVDATFGRGGHSRLLLSQLADDATLI
HHHHHHHHHHHHHHHHCCCCCCCCHHHCEECCCEEEEEECCCCCHHHHHHHHHCCCCEEE
VFDKDPTAISVARELANSDSRVKVVHDSFATLTDSLAAMRITQVDGLMADLGISSPQIDD
EECCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSRGFSFMRDGAVDMRMDTSRGQSVAEWLETVDDETLANVLYEFGEERHSRRIARAIKQM
CCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSYDSTLALAEVIKVAHPNWQRGKHPATQSFQAMRIFINNELGDVDNFLEQSIPILKVGG
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHEECCCCCCHHHHHHHHCCCEEEECC
QLAVISFHSLEDRRIKQFLQRHSKGQYPEDENLPMPPKRPRYFSKPKRVGPSKAEISHNP
EEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
RSRSAWLRMATRTDADYVADIHP
CHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA