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The map label for this gene is atpB [H]

Identifier: 93007157

GI number: 93007157

Start: 2862527

End: 2863393

Strand: Reverse

Name: atpB [H]

Synonym: Pcryo_2333

Alternate gene names: 93007157

Gene position: 2863393-2862527 (Counterclockwise)

Preceding gene: 93007158

Following gene: 93007156

Centisome position: 93.58

GC content: 41.18

Gene sequence:

>867_bases
ATGGCAGGCGAGCAAACAACAACAGAATATATCTCTCACCACTTAACGAACTGGACGTACGGCTATCTGCCGGGCGAAGG
TTGGAAAGTTGCCTATAATGCTGAAGAAGCTAGTGCAATGGGCTTTAAAGCTATCCACCTTGATTCTATGCTTTGGTCAA
TTGGTCTAGGCATTGTTTTCTGTGCCATCTTTTGGATGGTCGCTAGGAAAGTCACTTCAGGCGTACCGGGTAAAACTCAG
GCTGCGGTTGAGATGATCGTTGAGTTCGTTGATAACAACGTTCGTGATTCGTATAGTGGTACCTCAAAGCTGATTGCGCC
TTTGGCGTTGACTATCTTTGTATGGATATTCTTAATGAACTTGATGGATTTACTACCCGTCGACTTTATCCCTATGATTG
CTGGCCAAATCGGCGCACTGATGGGACATGATCCACATCATGTGTACTTTAAGATTGTTCCAACCACGGATCCTAATATC
ACGCTTGGCATGTCTTTTTCTGTCTTTATACTGATTCTGTTTTATAGTATCAAAGAAAAAGGTTTGGGCGGCTTTGTTGG
CGAGCTAACACTGCATCCGTTTAGTGCCAAAAATCCTATCGTACAAATTATTTTAATACCCATCAACTTTATCTTAGAGT
TTGTTACTCTGATAGCGAAACCTATCTCTTTAGGTTTACGACTATTCGGTAACATGTATGCTGGTGAGTTGATTTTCATA
CTGATTGCCTTAATGCCGTTTTGGATTCAATGGGCGTTATCAGTACCGTGGGCTATTTTCCACATCTTAATTATTACACT
TCAAGCGTTCGTATTTATGATGCTGACGATAGTTTATATGTCACTTGCATCATCAACTGAACATTAA

Upstream 100 bases:

>100_bases
TTGCTTTGTTGCAAGGCAGATAAACATACTAAAATCTCATCAGATGACAACCATATTTTTGGTAGTTGATTAAATCGTTG
ATTAATAAGAAGCTGACATT

Downstream 100 bases:

>100_bases
TTAGACATTCAATAGGTAAATGAGGATACATCCATGGATCCAGTATTAGGTGGTTACACAGTTATCGCAGTAGCACTACT
TATCGGTTTAGGTGCACTAG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAGEQTTTEYISHHLTNWTYGYLPGEGWKVAYNAEEASAMGFKAIHLDSMLWSIGLGIVFCAIFWMVARKVTSGVPGKTQ
AAVEMIVEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMNLMDLLPVDFIPMIAGQIGALMGHDPHHVYFKIVPTTDPNI
TLGMSFSVFILILFYSIKEKGLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFI
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH

Sequences:

>Translated_288_residues
MAGEQTTTEYISHHLTNWTYGYLPGEGWKVAYNAEEASAMGFKAIHLDSMLWSIGLGIVFCAIFWMVARKVTSGVPGKTQ
AAVEMIVEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMNLMDLLPVDFIPMIAGQIGALMGHDPHHVYFKIVPTTDPNI
TLGMSFSVFILILFYSIKEKGLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFI
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH
>Mature_287_residues
AGEQTTTEYISHHLTNWTYGYLPGEGWKVAYNAEEASAMGFKAIHLDSMLWSIGLGIVFCAIFWMVARKVTSGVPGKTQA
AVEMIVEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMNLMDLLPVDFIPMIAGQIGALMGHDPHHVYFKIVPTTDPNIT
LGMSFSVFILILFYSIKEKGLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFIL
IALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=290, Percent_Identity=56.2068965517241, Blast_Score=280, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 32159; Mature: 32028

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEQTTTEYISHHLTNWTYGYLPGEGWKVAYNAEEASAMGFKAIHLDSMLWSIGLGIVF
CCCCHHHHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
CAIFWMVARKVTSGVPGKTQAAVEMIVEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMDLLPVDFIPMIAGQIGALMGHDPHHVYFKIVPTTDPNITLGMSFSVFILILFYSIKEK
HHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHC
GLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFI
CCCCEEHHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGEQTTTEYISHHLTNWTYGYLPGEGWKVAYNAEEASAMGFKAIHLDSMLWSIGLGIVF
CCCHHHHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
CAIFWMVARKVTSGVPGKTQAAVEMIVEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMDLLPVDFIPMIAGQIGALMGHDPHHVYFKIVPTTDPNITLGMSFSVFILILFYSIKEK
HHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHC
GLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFI
CCCCEEHHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA