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The map label for this gene is uvrC [H]

Identifier: 93007140

GI number: 93007140

Start: 2843524

End: 2845461

Strand: Reverse

Name: uvrC [H]

Synonym: Pcryo_2316

Alternate gene names: 93007140

Gene position: 2845461-2843524 (Counterclockwise)

Preceding gene: 93007141

Following gene: 93007136

Centisome position: 92.99

GC content: 44.58

Gene sequence:

>1938_bases
ATGGTTATTGATAAGCTAATAAGGGTTCTTGTAAAACCCATACCATCGCCCCATAAACATCTGTATATCAGTATCTTGAG
AGCAATAAATTCTATGGTCAATGTCTCAGAATCGAGTCCCATCGATGACAAGAAAGCCCGTCTTAAACATTTAATCCAGC
GCCTGCCAAACTTGCCGGGAGTGTATAAAATGCTGGGTAAAAATGGTGATATTTTATATGTCGGCAAAGCTAAATCACTC
AAGAGCCGTGTGAACAGCTACTTTGCGAAAACCATTGATCATCCTAAGACACGAGCACTGGTGGCACGGATACATAATAT
TGAAACCATCATTACCCGCAGTGAAACCGAAGCGCTGTTACTTGAGCAAAATCTGATTAAAGAATATCGTCCGCCTTATA
ACGTACTGTTGCGCGATGATAAATCCTATCTCTATGTGTTTATTTCAGCAGATAAGCCTTATCCAAGATTGGCTTATGGT
CGTGGTAAAGGCAATCACCAAAAGGGTCGCTTTTTCGGTCCTTTTCCTTCTGCGCATGCGGCAAAAGAAACACTGGTGCT
CATGCAAAAAATGTTTCAAATGCGCCAATGCACCAATACCTTTTTTAAGCAACGTAAGCGTCCTTGTCTTGAATACCAAA
TTAAGCGTTGCCGTGCGCCATGTGTGGGCTTAGTATCGCCAGAAGAATATAGCGAGGACGTCAATAATACTATTCGTTTC
TTAAAAGGTGACTCTAGCGATATCCATACTGCTTTGATTGAAAAAATGGAAGCTTCTGCTGAAGAGCTAGACTTTGAAAA
GGCAGTTTTTTATCGCGATCAGCTTTCTATGCTGCGTGAAGTACAAGCCAAGCAAGCCGTTTATACAGTGCAGGGTGAGG
CAGATGTGATTGCTATTGCCAGTCAAGGAGGCATGACCTGTGTCAACGTATTGACGGTACGTGGTGGGCGCGTGCTTGGC
GGTAAGAACTACTTCCCTGATGTCGATAGCAGTGAGCCTCTTGCAGACAATTTATCAGCGTTTATCACCTCATTTTATTT
TCAGGTGACGGATGATTTGCCAGCAGAGATTATATTGAGCGATGAATTACCAGATCAGCTAGCAGTGAGTGAGGCGTTGG
CAACACACTTTGGTAGTAAGGTCGTTATCAAAACCAGCGTACGTGAGCACCGTGCTGAATGGTTAGACTTAGCAAAACTT
AATACTAATAATGCACTAAAAACCAAACTTGGCGATTATTTAGAGTTACATGCACGCTTTGGGGCGTTAAAAGATGTTTT
GACTGAAGTCACGGATCGTACCATTGACCGTATCGAGTGTTTTGATATCTCGCATACGATGGGCGAGGCGACGATTGGTA
GCTGTGTGGTCTTTGATCAAGGTGGCTCGCGTCGTCGTGATTATCGTCAGTATGCTATCCATGACATTGTCGGCGGTGAT
GACTATGCAGCGATGAAGCAGGTTTTGACACGGCGTTATAAGAAGCAGCCATTGCCGGATTTATTGCTTATCGATGGTGG
TAAAGGGCAGCTCGGTATAGCCAAAGAAGTGCTGACTGAGTTGGGTATCCTTGGTGATACTTTGCTTATCAGTGTGGCAA
AAGGTGAAGGACGTAAGGCTGGACTTGAAGTTCTGCACTTTATTGACCATGAGCCACTTGACTTGCCTATGGATAGCAAG
GCGCTGCATTTATTAATGCATATCCGCGATGAGGCGCATCGTTTTGCGATTACAGCGCACCGTAAAAAGCGTGATAAGCG
TCGTTCATCATCAGTGCTAGAAGTAATACCAGGACTGGGCGAAAAGCGCCGTCGTGATTTGCTCAATCACTTTGGCGGCA
TGCAGCAATTGCTTGGTGCCTCGCAGCAAGAATTGGCAGGCGTACAAGGTATTGGACCAGTACTCGCAAAAACCGTTTAT
AAAGTGCTGCATGAGTAG

Upstream 100 bases:

>100_bases
ATGTTGCCAGGTATCCCAGCACTATTACCAAATTTCCGTCACTAGTCGCACTGTAGGGTTGTTTTTCTGCAAAAAGTCAG
CCTTGGTGCTGGCTTTTTTT

Downstream 100 bases:

>100_bases
TCTAGGTAATGTTCGTCAAATTTAGGTTTATGTTCATAAAGTTTGAACATGAAAAAAGAGGCTGTCCTAGAGTTATTTAG
GATAGCCTCTTTTTACGTTT

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MVIDKLIRVLVKPIPSPHKHLYISILRAINSMVNVSESSPIDDKKARLKHLIQRLPNLPGVYKMLGKNGDILYVGKAKSL
KSRVNSYFAKTIDHPKTRALVARIHNIETIITRSETEALLLEQNLIKEYRPPYNVLLRDDKSYLYVFISADKPYPRLAYG
RGKGNHQKGRFFGPFPSAHAAKETLVLMQKMFQMRQCTNTFFKQRKRPCLEYQIKRCRAPCVGLVSPEEYSEDVNNTIRF
LKGDSSDIHTALIEKMEASAEELDFEKAVFYRDQLSMLREVQAKQAVYTVQGEADVIAIASQGGMTCVNVLTVRGGRVLG
GKNYFPDVDSSEPLADNLSAFITSFYFQVTDDLPAEIILSDELPDQLAVSEALATHFGSKVVIKTSVREHRAEWLDLAKL
NTNNALKTKLGDYLELHARFGALKDVLTEVTDRTIDRIECFDISHTMGEATIGSCVVFDQGGSRRRDYRQYAIHDIVGGD
DYAAMKQVLTRRYKKQPLPDLLLIDGGKGQLGIAKEVLTELGILGDTLLISVAKGEGRKAGLEVLHFIDHEPLDLPMDSK
ALHLLMHIRDEAHRFAITAHRKKRDKRRSSSVLEVIPGLGEKRRRDLLNHFGGMQQLLGASQQELAGVQGIGPVLAKTVY
KVLHE

Sequences:

>Translated_645_residues
MVIDKLIRVLVKPIPSPHKHLYISILRAINSMVNVSESSPIDDKKARLKHLIQRLPNLPGVYKMLGKNGDILYVGKAKSL
KSRVNSYFAKTIDHPKTRALVARIHNIETIITRSETEALLLEQNLIKEYRPPYNVLLRDDKSYLYVFISADKPYPRLAYG
RGKGNHQKGRFFGPFPSAHAAKETLVLMQKMFQMRQCTNTFFKQRKRPCLEYQIKRCRAPCVGLVSPEEYSEDVNNTIRF
LKGDSSDIHTALIEKMEASAEELDFEKAVFYRDQLSMLREVQAKQAVYTVQGEADVIAIASQGGMTCVNVLTVRGGRVLG
GKNYFPDVDSSEPLADNLSAFITSFYFQVTDDLPAEIILSDELPDQLAVSEALATHFGSKVVIKTSVREHRAEWLDLAKL
NTNNALKTKLGDYLELHARFGALKDVLTEVTDRTIDRIECFDISHTMGEATIGSCVVFDQGGSRRRDYRQYAIHDIVGGD
DYAAMKQVLTRRYKKQPLPDLLLIDGGKGQLGIAKEVLTELGILGDTLLISVAKGEGRKAGLEVLHFIDHEPLDLPMDSK
ALHLLMHIRDEAHRFAITAHRKKRDKRRSSSVLEVIPGLGEKRRRDLLNHFGGMQQLLGASQQELAGVQGIGPVLAKTVY
KVLHE
>Mature_645_residues
MVIDKLIRVLVKPIPSPHKHLYISILRAINSMVNVSESSPIDDKKARLKHLIQRLPNLPGVYKMLGKNGDILYVGKAKSL
KSRVNSYFAKTIDHPKTRALVARIHNIETIITRSETEALLLEQNLIKEYRPPYNVLLRDDKSYLYVFISADKPYPRLAYG
RGKGNHQKGRFFGPFPSAHAAKETLVLMQKMFQMRQCTNTFFKQRKRPCLEYQIKRCRAPCVGLVSPEEYSEDVNNTIRF
LKGDSSDIHTALIEKMEASAEELDFEKAVFYRDQLSMLREVQAKQAVYTVQGEADVIAIASQGGMTCVNVLTVRGGRVLG
GKNYFPDVDSSEPLADNLSAFITSFYFQVTDDLPAEIILSDELPDQLAVSEALATHFGSKVVIKTSVREHRAEWLDLAKL
NTNNALKTKLGDYLELHARFGALKDVLTEVTDRTIDRIECFDISHTMGEATIGSCVVFDQGGSRRRDYRQYAIHDIVGGD
DYAAMKQVLTRRYKKQPLPDLLLIDGGKGQLGIAKEVLTELGILGDTLLISVAKGEGRKAGLEVLHFIDHEPLDLPMDSK
ALHLLMHIRDEAHRFAITAHRKKRDKRRSSSVLEVIPGLGEKRRRDLLNHFGGMQQLLGASQQELAGVQGIGPVLAKTVY
KVLHE

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=612, Percent_Identity=48.3660130718954, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI1788037, Length=210, Percent_Identity=27.1428571428571, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 72497; Mature: 72497

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIDKLIRVLVKPIPSPHKHLYISILRAINSMVNVSESSPIDDKKARLKHLIQRLPNLPG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCH
VYKMLGKNGDILYVGKAKSLKSRVNSYFAKTIDHPKTRALVARIHNIETIITRSETEALL
HHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCHHHHH
LEQNLIKEYRPPYNVLLRDDKSYLYVFISADKPYPRLAYGRGKGNHQKGRFFGPFPSAHA
HHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCHHH
AKETLVLMQKMFQMRQCTNTFFKQRKRPCLEYQIKRCRAPCVGLVSPEEYSEDVNNTIRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHH
LKGDSSDIHTALIEKMEASAEELDFEKAVFYRDQLSMLREVQAKQAVYTVQGEADVIAIA
HCCCCCHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEE
SQGGMTCVNVLTVRGGRVLGGKNYFPDVDSSEPLADNLSAFITSFYFQVTDDLPAEIILS
CCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEC
DELPDQLAVSEALATHFGSKVVIKTSVREHRAEWLDLAKLNTNNALKTKLGDYLELHARF
CCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GALKDVLTEVTDRTIDRIECFDISHTMGEATIGSCVVFDQGGSRRRDYRQYAIHDIVGGD
HHHHHHHHHHHHHHHHHHEEEECHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
DYAAMKQVLTRRYKKQPLPDLLLIDGGKGQLGIAKEVLTELGILGDTLLISVAKGEGRKA
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHH
GLEVLHFIDHEPLDLPMDSKALHLLMHIRDEAHRFAITAHRKKRDKRRSSSVLEVIPGLG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCC
EKRRRDLLNHFGGMQQLLGASQQELAGVQGIGPVLAKTVYKVLHE
HHHHHHHHHHHCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIDKLIRVLVKPIPSPHKHLYISILRAINSMVNVSESSPIDDKKARLKHLIQRLPNLPG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCH
VYKMLGKNGDILYVGKAKSLKSRVNSYFAKTIDHPKTRALVARIHNIETIITRSETEALL
HHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCHHHHH
LEQNLIKEYRPPYNVLLRDDKSYLYVFISADKPYPRLAYGRGKGNHQKGRFFGPFPSAHA
HHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCHHH
AKETLVLMQKMFQMRQCTNTFFKQRKRPCLEYQIKRCRAPCVGLVSPEEYSEDVNNTIRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHH
LKGDSSDIHTALIEKMEASAEELDFEKAVFYRDQLSMLREVQAKQAVYTVQGEADVIAIA
HCCCCCHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEE
SQGGMTCVNVLTVRGGRVLGGKNYFPDVDSSEPLADNLSAFITSFYFQVTDDLPAEIILS
CCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEC
DELPDQLAVSEALATHFGSKVVIKTSVREHRAEWLDLAKLNTNNALKTKLGDYLELHARF
CCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GALKDVLTEVTDRTIDRIECFDISHTMGEATIGSCVVFDQGGSRRRDYRQYAIHDIVGGD
HHHHHHHHHHHHHHHHHHEEEECHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
DYAAMKQVLTRRYKKQPLPDLLLIDGGKGQLGIAKEVLTELGILGDTLLISVAKGEGRKA
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHH
GLEVLHFIDHEPLDLPMDSKALHLLMHIRDEAHRFAITAHRKKRDKRRSSSVLEVIPGLG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCC
EKRRRDLLNHFGGMQQLLGASQQELAGVQGIGPVLAKTVYKVLHE
HHHHHHHHHHHCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA