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The map label for this gene is tesB [H]

Identifier: 93007109

GI number: 93007109

Start: 2807642

End: 2808544

Strand: Reverse

Name: tesB [H]

Synonym: Pcryo_2285

Alternate gene names: 93007109

Gene position: 2808544-2807642 (Counterclockwise)

Preceding gene: 93007110

Following gene: 93007104

Centisome position: 91.79

GC content: 47.51

Gene sequence:

>903_bases
ATGTCTGATTATTCACAACTAATAGATGAGCTATTGGCTACCGTCGCGCTCATCGAAGTCAGCCCTGATGTATTTGAAGG
TAAAAGCCATGACTATGTCGGTGCCCGTATCTTTGGTGGGCAAGTTCTCGCACAAGCGATCATGGCAGCAGCGCATACGC
TTGATGAAGACAAGCCTTGTCACTCATTGCATGGGTATTTTTTGCGCGGCGGTGATATTAACCAGCCGGTGATTTATCAA
GTGCGCCGCTTACGTGATGGGCGTAGTTTGTCCGCGCGCGAAGTAACGGCAATTCAGTATAAGCAAGTACGTGGTAAGCC
GCCGGTTGAGCAAGTGATATTTTCAATGATTGCCTCTTTTTCACCGATGGAAGAGGGCTTAGAGTATCAAGAAGATATGC
CTGTTTATCCACCGCCTGAAGACTTACTTGCGGAGCAGGATCTAAAAGAAGACTATGTTGGTAAAGTTCCAGAGGCATTA
AAATCTCGTTTTATGCGCCGTCGTCATATCGAGATTAAACCGGTGAAACCGCGTGACCCGATCCATCCGGAACCAATGAA
GCCCAAACAAGCGAACTGGCTACGTATCCGTGAATTGGGTAATCAGCCGATTGCTATCCAGCAAGCATTATTGGCGTTTT
CCTCTGATTTTTATTTGGTCGGCACGGGGCTGATGTCACATGGTATCAGCTTTATGACCAGCGGCTTGCAAGCTGCTAGT
ATCGACCATTCGATGCATTTTCATCGTCACTTTGACCTAAATGATTGGCTGCTATATGACATGTGGAGTGATACGACATC
CAATGCGATGGGGCTCAATCATGGTCAGTTTTGGCAAGATGGTAAGCTGGTGGCGACCGTACAGCAAGAAGGCTTGATGC
GTTTGCGAGTGCCGAAGTCTTAA

Upstream 100 bases:

>100_bases
TTAAAACGCCATATCGGCTCAAGCCATATCGTCTTGATATTCTTTGGCGCTTATATCTAGATGCTTGGCGTTATTGATAA
AAATAAGGAAAGTAATCGTC

Downstream 100 bases:

>100_bases
GTTTTTATATTGCTATAAATAGAAAAAGCGACTTAGAATTATTCTGAGTCGCTTTTTTATGGCGTATACAATCGTTATTT
TAAGCGGATTTTTTAATGAT

Product: palmitoyl-CoA hydrolase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSDYSQLIDELLATVALIEVSPDVFEGKSHDYVGARIFGGQVLAQAIMAAAHTLDEDKPCHSLHGYFLRGGDINQPVIYQ
VRRLRDGRSLSAREVTAIQYKQVRGKPPVEQVIFSMIASFSPMEEGLEYQEDMPVYPPPEDLLAEQDLKEDYVGKVPEAL
KSRFMRRRHIEIKPVKPRDPIHPEPMKPKQANWLRIRELGNQPIAIQQALLAFSSDFYLVGTGLMSHGISFMTSGLQAAS
IDHSMHFHRHFDLNDWLLYDMWSDTTSNAMGLNHGQFWQDGKLVATVQQEGLMRLRVPKS

Sequences:

>Translated_300_residues
MSDYSQLIDELLATVALIEVSPDVFEGKSHDYVGARIFGGQVLAQAIMAAAHTLDEDKPCHSLHGYFLRGGDINQPVIYQ
VRRLRDGRSLSAREVTAIQYKQVRGKPPVEQVIFSMIASFSPMEEGLEYQEDMPVYPPPEDLLAEQDLKEDYVGKVPEAL
KSRFMRRRHIEIKPVKPRDPIHPEPMKPKQANWLRIRELGNQPIAIQQALLAFSSDFYLVGTGLMSHGISFMTSGLQAAS
IDHSMHFHRHFDLNDWLLYDMWSDTTSNAMGLNHGQFWQDGKLVATVQQEGLMRLRVPKS
>Mature_299_residues
SDYSQLIDELLATVALIEVSPDVFEGKSHDYVGARIFGGQVLAQAIMAAAHTLDEDKPCHSLHGYFLRGGDINQPVIYQV
RRLRDGRSLSAREVTAIQYKQVRGKPPVEQVIFSMIASFSPMEEGLEYQEDMPVYPPPEDLLAEQDLKEDYVGKVPEALK
SRFMRRRHIEIKPVKPRDPIHPEPMKPKQANWLRIRELGNQPIAIQQALLAFSSDFYLVGTGLMSHGISFMTSGLQAASI
DHSMHFHRHFDLNDWLLYDMWSDTTSNAMGLNHGQFWQDGKLVATVQQEGLMRLRVPKS

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=300, Percent_Identity=38, Blast_Score=180, Evalue=2e-45,
Organism=Escherichia coli, GI1786657, Length=277, Percent_Identity=41.8772563176895, Blast_Score=217, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI71988741, Length=272, Percent_Identity=29.0441176470588, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI212645202, Length=272, Percent_Identity=31.6176470588235, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17531889, Length=295, Percent_Identity=31.1864406779661, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI115532456, Length=295, Percent_Identity=31.1864406779661, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17531885, Length=294, Percent_Identity=29.9319727891156, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71982224, Length=282, Percent_Identity=28.7234042553192, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17558508, Length=288, Percent_Identity=29.5138888888889, Blast_Score=104, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 34043; Mature: 33912

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYSQLIDELLATVALIEVSPDVFEGKSHDYVGARIFGGQVLAQAIMAAAHTLDEDKPC
CCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCH
HSLHGYFLRGGDINQPVIYQVRRLRDGRSLSAREVTAIQYKQVRGKPPVEQVIFSMIASF
HHHCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
SPMEEGLEYQEDMPVYPPPEDLLAEQDLKEDYVGKVPEALKSRFMRRRHIEIKPVKPRDP
CCHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCC
IHPEPMKPKQANWLRIRELGNQPIAIQQALLAFSSDFYLVGTGLMSHGISFMTSGLQAAS
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCEEEEEHHHHHHCHHHHHCCCHHHH
IDHSMHFHRHFDLNDWLLYDMWSDTTSNAMGLNHGQFWQDGKLVATVQQEGLMRLRVPKS
HHHHHHHEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCC
>Mature Secondary Structure 
SDYSQLIDELLATVALIEVSPDVFEGKSHDYVGARIFGGQVLAQAIMAAAHTLDEDKPC
CHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCH
HSLHGYFLRGGDINQPVIYQVRRLRDGRSLSAREVTAIQYKQVRGKPPVEQVIFSMIASF
HHHCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
SPMEEGLEYQEDMPVYPPPEDLLAEQDLKEDYVGKVPEALKSRFMRRRHIEIKPVKPRDP
CCHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCC
IHPEPMKPKQANWLRIRELGNQPIAIQQALLAFSSDFYLVGTGLMSHGISFMTSGLQAAS
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCEEEEEHHHHHHCHHHHHCCCHHHH
IDHSMHFHRHFDLNDWLLYDMWSDTTSNAMGLNHGQFWQDGKLVATVQQEGLMRLRVPKS
HHHHHHHEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]