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The map label for this gene is corC [H]

Identifier: 93007101

GI number: 93007101

Start: 2797612

End: 2798511

Strand: Reverse

Name: corC [H]

Synonym: Pcryo_2277

Alternate gene names: 93007101

Gene position: 2798511-2797612 (Counterclockwise)

Preceding gene: 93007104

Following gene: 93007100

Centisome position: 91.46

GC content: 47.0

Gene sequence:

>900_bases
ATGTCTGAAGATGCTCCAAGCCCGAGTAGTTGGTCGATGCGCGGCTTAAAACGCTGGCTATCGACCGCCCCCGAAACCCG
AGATGAACTGATACGTTTGGTGCAAGACTCGCGCCAATTTCTAGAACCTGACACCGTGGATATGTTAGAAGGTGTGCTTG
ATTTGCCTGCAACACAAGTGCGTGAAATCATGACACCGCGCCCGCAGGTGGTTGGGCTACACGAAAGCGCCAGCCTCGCT
GAAGTCATGGATATCATCCTTGAAACCACCCATTCGCGCTATCCGGTTTTTGATAGCCAAGATGACGATGCGGTCATTGG
TATTCTGTTGGCAAAAGATTTGATTCCTCTGTTGGTGCACATGGTGCGCGATGAAGAAGAGAAAATCAGTAGCAAGCGCT
TAAGAGATTTGGTGCGTCAGCCACTCTATATCAGTGAAAGTGCACGCTCTGATACTTTGCTGCGCTCATTACAGCGTACC
CAAGTTCATATGGCGATTGTTGTCGATGAATTTGGCAATTTTGGTGGTGTGGTCACGATGGAGGATTTGCTTGAGGAAAT
CGTCGGTGACATCGTCGATGAGCATGATGATTTTGATGAAGACAGTGACATTAATAATATCGTCGCTGACCCTGAAAAGC
CCAATACTTGGCGTGTCCAAGCGTCTACCGTGATTGAAGATTGTAACGATGAGCTTGGCTGTCATTTTGATGATACTGAT
GTCGATACTATGGGTGGCTTGGTCATGCAGACCCTTGGTCATGTCGGAGATTTAGAAGGTGAGAGCGTGGTCATAGACGA
TTGGCAAATCACTATCACTGATGTCGAAGGGCGTTTTATTCAAAATCTTGAGCTGACTAAAATTAATCCTGAACAACAAA
TCTTGATTGGCAGCCATTAA

Upstream 100 bases:

>100_bases
ATGATAAGCTGACTGTTTTATTTAGCCTTTTTATCCCCATCTATCATTTTTATGATTCTAATTGCCATTACATTAATTAA
AGAGGTTAACTCACACCATC

Downstream 100 bases:

>100_bases
ACACTTTGTTGAATAAGTTGAGCCTATTGATTAGAGCTATTAAAGATACGCTTAATAAAGGTCATAAGCATACAAAAAAC
ACGATTGCGATCGTGTTTTT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSEDAPSPSSWSMRGLKRWLSTAPETRDELIRLVQDSRQFLEPDTVDMLEGVLDLPATQVREIMTPRPQVVGLHESASLA
EVMDIILETTHSRYPVFDSQDDDAVIGILLAKDLIPLLVHMVRDEEEKISSKRLRDLVRQPLYISESARSDTLLRSLQRT
QVHMAIVVDEFGNFGGVVTMEDLLEEIVGDIVDEHDDFDEDSDINNIVADPEKPNTWRVQASTVIEDCNDELGCHFDDTD
VDTMGGLVMQTLGHVGDLEGESVVIDDWQITITDVEGRFIQNLELTKINPEQQILIGSH

Sequences:

>Translated_299_residues
MSEDAPSPSSWSMRGLKRWLSTAPETRDELIRLVQDSRQFLEPDTVDMLEGVLDLPATQVREIMTPRPQVVGLHESASLA
EVMDIILETTHSRYPVFDSQDDDAVIGILLAKDLIPLLVHMVRDEEEKISSKRLRDLVRQPLYISESARSDTLLRSLQRT
QVHMAIVVDEFGNFGGVVTMEDLLEEIVGDIVDEHDDFDEDSDINNIVADPEKPNTWRVQASTVIEDCNDELGCHFDDTD
VDTMGGLVMQTLGHVGDLEGESVVIDDWQITITDVEGRFIQNLELTKINPEQQILIGSH
>Mature_298_residues
SEDAPSPSSWSMRGLKRWLSTAPETRDELIRLVQDSRQFLEPDTVDMLEGVLDLPATQVREIMTPRPQVVGLHESASLAE
VMDIILETTHSRYPVFDSQDDDAVIGILLAKDLIPLLVHMVRDEEEKISSKRLRDLVRQPLYISESARSDTLLRSLQRTQ
VHMAIVVDEFGNFGGVVTMEDLLEEIVGDIVDEHDDFDEDSDINNIVADPEKPNTWRVQASTVIEDCNDELGCHFDDTDV
DTMGGLVMQTLGHVGDLEGESVVIDDWQITITDVEGRFIQNLELTKINPEQQILIGSH

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=205, Percent_Identity=32.1951219512195, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1786879, Length=267, Percent_Identity=41.5730337078652, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI145693175, Length=265, Percent_Identity=24.1509433962264, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082033, Length=250, Percent_Identity=27.6, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788119, Length=306, Percent_Identity=29.7385620915033, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324512, Length=163, Percent_Identity=32.5153374233129, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33645; Mature: 33514

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDAPSPSSWSMRGLKRWLSTAPETRDELIRLVQDSRQFLEPDTVDMLEGVLDLPATQV
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHH
REIMTPRPQVVGLHESASLAEVMDIILETTHSRYPVFDSQDDDAVIGILLAKDLIPLLVH
HHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MVRDEEEKISSKRLRDLVRQPLYISESARSDTLLRSLQRTQVHMAIVVDEFGNFGGVVTM
HHCCHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEH
EDLLEEIVGDIVDEHDDFDEDSDINNIVADPEKPNTWRVQASTVIEDCNDELGCHFDDTD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCC
VDTMGGLVMQTLGHVGDLEGESVVIDDWQITITDVEGRFIQNLELTKINPEQQILIGSH
HHHHHHHHHHHHHHHCCCCCCEEEEECEEEEEEECCCHHHCCEEEEEECCCCEEEECCC
>Mature Secondary Structure 
SEDAPSPSSWSMRGLKRWLSTAPETRDELIRLVQDSRQFLEPDTVDMLEGVLDLPATQV
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHH
REIMTPRPQVVGLHESASLAEVMDIILETTHSRYPVFDSQDDDAVIGILLAKDLIPLLVH
HHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MVRDEEEKISSKRLRDLVRQPLYISESARSDTLLRSLQRTQVHMAIVVDEFGNFGGVVTM
HHCCHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEH
EDLLEEIVGDIVDEHDDFDEDSDINNIVADPEKPNTWRVQASTVIEDCNDELGCHFDDTD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCC
VDTMGGLVMQTLGHVGDLEGESVVIDDWQITITDVEGRFIQNLELTKINPEQQILIGSH
HHHHHHHHHHHHHHHCCCCCCEEEEECEEEEEEECCCHHHCCEEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]