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The map label for this gene is 93007028

Identifier: 93007028

GI number: 93007028

Start: 2708547

End: 2709596

Strand: Direct

Name: 93007028

Synonym: Pcryo_2204

Alternate gene names: NA

Gene position: 2708547-2709596 (Clockwise)

Preceding gene: 93007027

Following gene: 93007029

Centisome position: 88.52

GC content: 46.95

Gene sequence:

>1050_bases
ATGAGTGAAGCATCAGAGCAAATTTCAGCTAAGAATAATACACACTATCGCTATTTGGTGTTTATCGGGCGTTTTCAGCC
CTTTCATTGTGGTCATAAAGCAGTTATTGATGAGGCACTCAAGCGGGCTGACAATGTGATTATGCTCATCGGTTCTGCTA
ATCTGCCACGTAGTTTGCGAAATCCTTTTAGTGTTGCTGAGCGCGCGTCTATGATTAAGGGTGCCTATTCAGTAGAGCAA
GCTGCGCGTATCCACTGCGTTGGACTCGATGATGCACTCTACAATGACACGCGTTGGCTACAATATGTACAAGCAGGCGT
TAAATCCGTCACTGGCGACTTACAGACTGATATCGGTCTGATTGGTCACTCAAAAGACAGCTCATCGTATTATTTATCTT
TGTTCCCCAACTGGGCATCTGTCTCCGTACCCAATTATCATAACTTATCCGCCACGCCTATACGTGACAGCTACTTAATG
GGTGCTACGCCAACACCTGAGCGCACCCCTGAGTCAACGCGCAACGTATTGGATGAATTCAAGAAAACAAGCGAATATCA
ACAACTGCACGATGAAGCCGATTTTGTTGATAAGTATAAAAGACAATGGGAGTCTGCTCCTTATCCGCCAACCTTTATGA
CTGCCGATGCCTTAGTCGTACAGTCAGGACATATCTTGCTGGTTGAGCGCCGTAGTATGCCGGGGCAAGGATTGTGGGCA
CTACCGGGTGGGTTTTTAAACCCAAAAGAGACACTATTTGACGCCTGTATCCGTGAGCTCCGTGAGGAGACTCGCCTCAA
AGTCCCTGAGCCCGTATTGCGTGGCTCTTGTCATAGTCAGCATACCTTTGATGATCCTTACCGCTCAGCGCGTGGGCGTA
CGATTACTCAAGCATTTTATTTTCAGCTAAAAAACGACCCAAAAGGCTTGCCAAAAGTAAAAGGCGGCGATGACGCAGCC
ACAGCGTTTTGGTTACCGCTCGCCGAGCTTGATGCCAAAATGATGTTTGAAGATCATTATGCCATTATCACCAAAATGGT
CGGCTTATAG

Upstream 100 bases:

>100_bases
AATTATTTTGAATTGATAATATTTTGAATCCTAGTTAATAACCAATAATTAAAAAATCCCCATTAATAATTGATAGCAGT
ACGGCAGGAGCTGGGCGTTT

Downstream 100 bases:

>100_bases
TATTTTATCAGACGGCTATGCGATCCTTTATTAATAATTTCCTAAACCGATAGACGGTAAAGGCTTCGCGCCGCCATCGT
TGCGGCATCTCAAAGCAGAG

Product: bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSEASEQISAKNNTHYRYLVFIGRFQPFHCGHKAVIDEALKRADNVIMLIGSANLPRSLRNPFSVAERASMIKGAYSVEQ
AARIHCVGLDDALYNDTRWLQYVQAGVKSVTGDLQTDIGLIGHSKDSSSYYLSLFPNWASVSVPNYHNLSATPIRDSYLM
GATPTPERTPESTRNVLDEFKKTSEYQQLHDEADFVDKYKRQWESAPYPPTFMTADALVVQSGHILLVERRSMPGQGLWA
LPGGFLNPKETLFDACIRELREETRLKVPEPVLRGSCHSQHTFDDPYRSARGRTITQAFYFQLKNDPKGLPKVKGGDDAA
TAFWLPLAELDAKMMFEDHYAIITKMVGL

Sequences:

>Translated_349_residues
MSEASEQISAKNNTHYRYLVFIGRFQPFHCGHKAVIDEALKRADNVIMLIGSANLPRSLRNPFSVAERASMIKGAYSVEQ
AARIHCVGLDDALYNDTRWLQYVQAGVKSVTGDLQTDIGLIGHSKDSSSYYLSLFPNWASVSVPNYHNLSATPIRDSYLM
GATPTPERTPESTRNVLDEFKKTSEYQQLHDEADFVDKYKRQWESAPYPPTFMTADALVVQSGHILLVERRSMPGQGLWA
LPGGFLNPKETLFDACIRELREETRLKVPEPVLRGSCHSQHTFDDPYRSARGRTITQAFYFQLKNDPKGLPKVKGGDDAA
TAFWLPLAELDAKMMFEDHYAIITKMVGL
>Mature_348_residues
SEASEQISAKNNTHYRYLVFIGRFQPFHCGHKAVIDEALKRADNVIMLIGSANLPRSLRNPFSVAERASMIKGAYSVEQA
ARIHCVGLDDALYNDTRWLQYVQAGVKSVTGDLQTDIGLIGHSKDSSSYYLSLFPNWASVSVPNYHNLSATPIRDSYLMG
ATPTPERTPESTRNVLDEFKKTSEYQQLHDEADFVDKYKRQWESAPYPPTFMTADALVVQSGHILLVERRSMPGQGLWAL
PGGFLNPKETLFDACIRELREETRLKVPEPVLRGSCHSQHTFDDPYRSARGRTITQAFYFQLKNDPKGLPKVKGGDDAAT
AFWLPLAELDAKMMFEDHYAIITKMVGL

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 39298; Mature: 39167

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEASEQISAKNNTHYRYLVFIGRFQPFHCGHKAVIDEALKRADNVIMLIGSANLPRSLR
CCCHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHC
NPFSVAERASMIKGAYSVEQAARIHCVGLDDALYNDTRWLQYVQAGVKSVTGDLQTDIGL
CHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCEE
IGHSKDSSSYYLSLFPNWASVSVPNYHNLSATPIRDSYLMGATPTPERTPESTRNVLDEF
EECCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHH
KKTSEYQQLHDEADFVDKYKRQWESAPYPPTFMTADALVVQSGHILLVERRSMPGQGLWA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEECCCEEEEECCCCCCCCEEE
LPGGFLNPKETLFDACIRELREETRLKVPEPVLRGSCHSQHTFDDPYRSARGRTITQAFY
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHCCCEEEEEEE
FQLKNDPKGLPKVKGGDDAATAFWLPLAELDAKMMFEDHYAIITKMVGL
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEASEQISAKNNTHYRYLVFIGRFQPFHCGHKAVIDEALKRADNVIMLIGSANLPRSLR
CCHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHC
NPFSVAERASMIKGAYSVEQAARIHCVGLDDALYNDTRWLQYVQAGVKSVTGDLQTDIGL
CHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCEE
IGHSKDSSSYYLSLFPNWASVSVPNYHNLSATPIRDSYLMGATPTPERTPESTRNVLDEF
EECCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHH
KKTSEYQQLHDEADFVDKYKRQWESAPYPPTFMTADALVVQSGHILLVERRSMPGQGLWA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEECCCEEEEECCCCCCCCEEE
LPGGFLNPKETLFDACIRELREETRLKVPEPVLRGSCHSQHTFDDPYRSARGRTITQAFY
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCHHHHHCCCEEEEEEE
FQLKNDPKGLPKVKGGDDAATAFWLPLAELDAKMMFEDHYAIITKMVGL
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]