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The map label for this gene is murA [H]

Identifier: 93007018

GI number: 93007018

Start: 2697918

End: 2699186

Strand: Reverse

Name: murA [H]

Synonym: Pcryo_2194

Alternate gene names: 93007018

Gene position: 2699186-2697918 (Counterclockwise)

Preceding gene: 93007019

Following gene: 93007017

Centisome position: 88.21

GC content: 47.28

Gene sequence:

>1269_bases
ATGGATCAATTTTTAATCACTGGTAGTAGTCGTATCGCAGGGGAAGTCACCATTTCAGGCGCTAAAAATGCCGCGTTGCC
GTTGCTTGCGGCTATGATATTGGCTGAGACGCCGACGACATTGCACAATGTGCCATCGCTACAAGATGTGCGCACTTTGA
TTGAGTTGATCGGTGGCATGGGTATCAAAATCCAAAAGCAGGGTGATACCGTCACTTGCGATACCAAGAGTATCGATAAT
TTTTATGCGCCTTATGATTTGGTTAAAACCATGCGCGCCTCAATCTTAGTACTGGGTCCATTGTTGGCACGTTTTGGTGA
GGCAGAAGTATCCTTGCCGGGTGGTTGTGCGATTGGTTCGCGCCCCGTTGATCAGCATCTTAAAGCCTTTGAAGCAATGG
GTGCTAGTATTACAGTGGAAAACGGCTATGTAATTGCGCAAGCACCAAAGGGCGGTAAGCTGTTAGGTTGTAAGTTCTCA
TTTGACATGGTAACGGTAGGCGGTACTGAAAACGTCATCATGGCAGCAGCACTTGCTAAAGGCACGACTGTTTTGGGTAA
CTGTGCGCTTGAGCCAGAAGTGGTTGATTTGGCTAATATGCTGGTCGCAATGGGTGCTAAAATTAGTGGTATTGGTACAG
CAACCATGACGATTGAAGGCGTTGAGCGCTTGCATGGCTGTGAGTATTCAGTCGTGCCAGACCGTATCGAAACAGGCTCT
TACCTTGCTGGTGCTTTGATGACACACGGTGATGTATTGACTAAGAATACTTCTGCGCTACTATTAACACCTGTGCTAGA
AAAGTTTGAAGACATGGGTGCAATTATCACTACGGGTGATGATTGGATTCGCGCACAAATGAAAGGTCGACCAAAAGCGG
TCGATATTCGTACCCAGCCGCATCCAGGTTTTCCAACGGATATGCAGGCACAGGTGATGGCGATTGCTTGTTTGGCTGAT
GGCACCAGTACCTTTATCGAAAATATCTTTGAGAACCGTTATATGCATGTCCCTGAGCTTAATCGTTTGGGTGCCTCTAT
CCAAGTAGACGGTCATACGGCTGTGGTAAAAGGGGTTGAATGCTTTACAGCCGCGCCTGTGATGGCGACTGATTTGCGTG
CTTCGATGTCATTGGTAATGGCAGCCGCAACAGCAGAAGGTGAGAGTTTAATTGACCGCATTTACCATATCGACCGTGGC
TATGAGCACGTTGAAGACAAATTGCGTGCGCTTGGTGTCAATATCGAGCGTATTAACAGCAACGATTAA

Upstream 100 bases:

>100_bases
TATTTACGACTGGATTGTTTATTACGAGCAAGTATTTTTGCCGCTAATAACCGATTCGGTTTTTCATTATTTTTATACTT
ATCGTTAGGTTGTCACCTTT

Downstream 100 bases:

>100_bases
TTGGCTTGCTAAAAGTTATAACGCTAGTATTAATACTGGCGTTATAATCAAAATAAATTTTAAGCCTAGTGTAATATTAA
AAATGCCCTTTGACGGCGAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDQFLITGSSRIAGEVTISGAKNAALPLLAAMILAETPTTLHNVPSLQDVRTLIELIGGMGIKIQKQGDTVTCDTKSIDN
FYAPYDLVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFEAMGASITVENGYVIAQAPKGGKLLGCKFS
FDMVTVGGTENVIMAAALAKGTTVLGNCALEPEVVDLANMLVAMGAKISGIGTATMTIEGVERLHGCEYSVVPDRIETGS
YLAGALMTHGDVLTKNTSALLLTPVLEKFEDMGAIITTGDDWIRAQMKGRPKAVDIRTQPHPGFPTDMQAQVMAIACLAD
GTSTFIENIFENRYMHVPELNRLGASIQVDGHTAVVKGVECFTAAPVMATDLRASMSLVMAAATAEGESLIDRIYHIDRG
YEHVEDKLRALGVNIERINSND

Sequences:

>Translated_422_residues
MDQFLITGSSRIAGEVTISGAKNAALPLLAAMILAETPTTLHNVPSLQDVRTLIELIGGMGIKIQKQGDTVTCDTKSIDN
FYAPYDLVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFEAMGASITVENGYVIAQAPKGGKLLGCKFS
FDMVTVGGTENVIMAAALAKGTTVLGNCALEPEVVDLANMLVAMGAKISGIGTATMTIEGVERLHGCEYSVVPDRIETGS
YLAGALMTHGDVLTKNTSALLLTPVLEKFEDMGAIITTGDDWIRAQMKGRPKAVDIRTQPHPGFPTDMQAQVMAIACLAD
GTSTFIENIFENRYMHVPELNRLGASIQVDGHTAVVKGVECFTAAPVMATDLRASMSLVMAAATAEGESLIDRIYHIDRG
YEHVEDKLRALGVNIERINSND
>Mature_422_residues
MDQFLITGSSRIAGEVTISGAKNAALPLLAAMILAETPTTLHNVPSLQDVRTLIELIGGMGIKIQKQGDTVTCDTKSIDN
FYAPYDLVKTMRASILVLGPLLARFGEAEVSLPGGCAIGSRPVDQHLKAFEAMGASITVENGYVIAQAPKGGKLLGCKFS
FDMVTVGGTENVIMAAALAKGTTVLGNCALEPEVVDLANMLVAMGAKISGIGTATMTIEGVERLHGCEYSVVPDRIETGS
YLAGALMTHGDVLTKNTSALLLTPVLEKFEDMGAIITTGDDWIRAQMKGRPKAVDIRTQPHPGFPTDMQAQVMAIACLAD
GTSTFIENIFENRYMHVPELNRLGASIQVDGHTAVVKGVECFTAAPVMATDLRASMSLVMAAATAEGESLIDRIYHIDRG
YEHVEDKLRALGVNIERINSND

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=54.5238095238095, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44838; Mature: 44838

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQFLITGSSRIAGEVTISGAKNAALPLLAAMILAETPTTLHNVPSLQDVRTLIELIGGM
CCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCC
GIKIQKQGDTVTCDTKSIDNFYAPYDLVKTMRASILVLGPLLARFGEAEVSLPGGCAIGS
CEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHLKAFEAMGASITVENGYVIAQAPKGGKLLGCKFSFDMVTVGGTENVIMAAALAK
CCHHHHHHHHHHCCCEEEEECCEEEEECCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHC
GTTVLGNCALEPEVVDLANMLVAMGAKISGIGTATMTIEGVERLHGCEYSVVPDRIETGS
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCCCCEEECCCCCCCCC
YLAGALMTHGDVLTKNTSALLLTPVLEKFEDMGAIITTGDDWIRAQMKGRPKAVDIRTQP
HHHHHHHHCCCEEECCCCEEEEHHHHHHHHHCCEEEECCCHHHHHHHCCCCCEEEEECCC
HPGFPTDMQAQVMAIACLADGTSTFIENIFENRYMHVPELNRLGASIQVDGHTAVVKGVE
CCCCCCCCHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCEEEEECCH
CFTAAPVMATDLRASMSLVMAAATAEGESLIDRIYHIDRGYEHVEDKLRALGVNIERINS
HHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCC
ND
CC
>Mature Secondary Structure
MDQFLITGSSRIAGEVTISGAKNAALPLLAAMILAETPTTLHNVPSLQDVRTLIELIGGM
CCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCC
GIKIQKQGDTVTCDTKSIDNFYAPYDLVKTMRASILVLGPLLARFGEAEVSLPGGCAIGS
CEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHLKAFEAMGASITVENGYVIAQAPKGGKLLGCKFSFDMVTVGGTENVIMAAALAK
CCHHHHHHHHHHCCCEEEEECCEEEEECCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHC
GTTVLGNCALEPEVVDLANMLVAMGAKISGIGTATMTIEGVERLHGCEYSVVPDRIETGS
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCCCCEEECCCCCCCCC
YLAGALMTHGDVLTKNTSALLLTPVLEKFEDMGAIITTGDDWIRAQMKGRPKAVDIRTQP
HHHHHHHHCCCEEECCCCEEEEHHHHHHHHHCCEEEECCCHHHHHHHCCCCCEEEEECCC
HPGFPTDMQAQVMAIACLADGTSTFIENIFENRYMHVPELNRLGASIQVDGHTAVVKGVE
CCCCCCCCHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCEEEEECCH
CFTAAPVMATDLRASMSLVMAAATAEGESLIDRIYHIDRGYEHVEDKLRALGVNIERINS
HHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCC
ND
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA