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The map label for this gene is hisC2 [H]

Identifier: 93007015

GI number: 93007015

Start: 2694311

End: 2695444

Strand: Reverse

Name: hisC2 [H]

Synonym: Pcryo_2191

Alternate gene names: 93007015

Gene position: 2695444-2694311 (Counterclockwise)

Preceding gene: 93007016

Following gene: 93007012

Centisome position: 88.09

GC content: 43.92

Gene sequence:

>1134_bases
ATGAGTGAATCAAAGATAGATAACAGACTTTGGTCATCTAAAGCGCGTAATTTATCGCCGTATGTTCCTGGTGAGCAGCC
CCAGCATGACGATTTGTGCAAGTTGAACACCAATGAAAATCCATTTCCACCTTCACCAAAAGTAGGTGAGGCGATTATTA
AAGTCTTAGCGCAGCAAGCGGATGATTTGCGCTTGTACCCTGCACCTGAGTCTGAAGAATTGCGCGGCGCATTGGCCACG
CTTTATGATCTTGATATCAATCAAGTGTTCGTTGGTAATGGCTCAGATGAAGTATTGGCATTGGTATTCGCCAGCTTCTT
CTTAAAAGAGCGCCCAATTTTAGCGCCTGATATTAGCTACAGCTTTTATCCCGTTTATGCCAATACCTTTGGTATAGAGC
TTGTGCAAATCCCATTAGAAGCAGATTTTAGTATCAGTCCTGATGCCTATCGTCGACCTTGCAGTGGTATCATTATTGCC
AATCCAAATGCGCCAACTGGTTTATTATTGTCGCTTGCTGATATCCGTAAGCTTGCAGGCGAGCACTCAAATTCAGTGAT
TGTGATTGATGAGGCGTATATCGATTTTGCTCAGCTAGAAGAGAGTAGTCCAGACGTAGAAGTATCAGCGGTTAACCTTA
TTAATGAATTTGATAACTTGCTAGTTACCCAGACCTTTTCAAAATCGCGTTCGCTTGCCGGACTGCGTGTCGGTATGGCA
TTTGGTAATGCCTCTTTGATTGAAGCATTAACGCGTATGAAAAACAGCTTTAATAGCTATCCACTTGATAAGTTGGCACA
AGCTGGTGCAACAGCTAGCGTCTTAGATGTTGAATATTTTGAGAAAACCCGCCAGCAGGTCATTGATTTGCGTACATCGT
TGACGGTTGAGTTGACGGCCTTAGGTTATGACGTACTGCCGTCACATGCCAACTTTGTCTTTGCGCGTCCTCATGATGGT
GCTGCCAGTCAAGTAGCAGAAGTATTACGTGAGCAAGGTATCATTGTTCGTCATTTTGATAAGCCGCGTATTAATGAGTA
TTTGCGCATTACGATTGGCACCGCTGCCCAGAACGAGCGTTTAATTGATGCGTTAAAAGCGCTACAAACTGTAGCGGATG
TCGAGGCAAATTAA

Upstream 100 bases:

>100_bases
TTTTCAAAGACAATTATTGGAATAACAGGTCTTTGGATAACAACTTTTAGAATAACAGTTTTAGAAATAACCATTTCTGT
GATTAATAGTAGGATAACTT

Downstream 100 bases:

>100_bases
TACCTAGCTCAACTATAGTACTAAAACAATATTTCATAAGTAATAAAAAGAGCCTGCTCACATGATGTGAGCAGGCTCTT
TTGCGCCGCTTTAAGCTGTT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSESKIDNRLWSSKARNLSPYVPGEQPQHDDLCKLNTNENPFPPSPKVGEAIIKVLAQQADDLRLYPAPESEELRGALAT
LYDLDINQVFVGNGSDEVLALVFASFFLKERPILAPDISYSFYPVYANTFGIELVQIPLEADFSISPDAYRRPCSGIIIA
NPNAPTGLLLSLADIRKLAGEHSNSVIVIDEAYIDFAQLEESSPDVEVSAVNLINEFDNLLVTQTFSKSRSLAGLRVGMA
FGNASLIEALTRMKNSFNSYPLDKLAQAGATASVLDVEYFEKTRQQVIDLRTSLTVELTALGYDVLPSHANFVFARPHDG
AASQVAEVLREQGIIVRHFDKPRINEYLRITIGTAAQNERLIDALKALQTVADVEAN

Sequences:

>Translated_377_residues
MSESKIDNRLWSSKARNLSPYVPGEQPQHDDLCKLNTNENPFPPSPKVGEAIIKVLAQQADDLRLYPAPESEELRGALAT
LYDLDINQVFVGNGSDEVLALVFASFFLKERPILAPDISYSFYPVYANTFGIELVQIPLEADFSISPDAYRRPCSGIIIA
NPNAPTGLLLSLADIRKLAGEHSNSVIVIDEAYIDFAQLEESSPDVEVSAVNLINEFDNLLVTQTFSKSRSLAGLRVGMA
FGNASLIEALTRMKNSFNSYPLDKLAQAGATASVLDVEYFEKTRQQVIDLRTSLTVELTALGYDVLPSHANFVFARPHDG
AASQVAEVLREQGIIVRHFDKPRINEYLRITIGTAAQNERLIDALKALQTVADVEAN
>Mature_376_residues
SESKIDNRLWSSKARNLSPYVPGEQPQHDDLCKLNTNENPFPPSPKVGEAIIKVLAQQADDLRLYPAPESEELRGALATL
YDLDINQVFVGNGSDEVLALVFASFFLKERPILAPDISYSFYPVYANTFGIELVQIPLEADFSISPDAYRRPCSGIIIAN
PNAPTGLLLSLADIRKLAGEHSNSVIVIDEAYIDFAQLEESSPDVEVSAVNLINEFDNLLVTQTFSKSRSLAGLRVGMAF
GNASLIEALTRMKNSFNSYPLDKLAQAGATASVLDVEYFEKTRQQVIDLRTSLTVELTALGYDVLPSHANFVFARPHDGA
ASQVAEVLREQGIIVRHFDKPRINEYLRITIGTAAQNERLIDALKALQTVADVEAN

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=367, Percent_Identity=29.700272479564, Blast_Score=117, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6322075, Length=399, Percent_Identity=29.0726817042606, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 41471; Mature: 41340

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESKIDNRLWSSKARNLSPYVPGEQPQHDDLCKLNTNENPFPPSPKVGEAIIKVLAQQA
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCC
DDLRLYPAPESEELRGALATLYDLDINQVFVGNGSDEVLALVFASFFLKERPILAPDISY
CCCEEECCCCCHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCC
SFYPVYANTFGIELVQIPLEADFSISPDAYRRPCSGIIIANPNAPTGLLLSLADIRKLAG
EEEEEEECCCCEEEEEEECCCCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHC
EHSNSVIVIDEAYIDFAQLEESSPDVEVSAVNLINEFDNLLVTQTFSKSRSLAGLRVGMA
CCCCCEEEEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHEEEHHHHHCCCCCCEEEEEE
FGNASLIEALTRMKNSFNSYPLDKLAQAGATASVLDVEYFEKTRQQVIDLRTSLTVELTA
CCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEE
LGYDVLPSHANFVFARPHDGAASQVAEVLREQGIIVRHFDKPRINEYLRITIGTAAQNER
ECCEECCCCCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCHH
LIDALKALQTVADVEAN
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SESKIDNRLWSSKARNLSPYVPGEQPQHDDLCKLNTNENPFPPSPKVGEAIIKVLAQQA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCC
DDLRLYPAPESEELRGALATLYDLDINQVFVGNGSDEVLALVFASFFLKERPILAPDISY
CCCEEECCCCCHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCC
SFYPVYANTFGIELVQIPLEADFSISPDAYRRPCSGIIIANPNAPTGLLLSLADIRKLAG
EEEEEEECCCCEEEEEEECCCCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHC
EHSNSVIVIDEAYIDFAQLEESSPDVEVSAVNLINEFDNLLVTQTFSKSRSLAGLRVGMA
CCCCCEEEEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHEEEHHHHHCCCCCCEEEEEE
FGNASLIEALTRMKNSFNSYPLDKLAQAGATASVLDVEYFEKTRQQVIDLRTSLTVELTA
CCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEEE
LGYDVLPSHANFVFARPHDGAASQVAEVLREQGIIVRHFDKPRINEYLRITIGTAAQNER
ECCEECCCCCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCHH
LIDALKALQTVADVEAN
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA