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The map label for this gene is ahpC [H]

Identifier: 93006902

GI number: 93006902

Start: 2544758

End: 2545324

Strand: Reverse

Name: ahpC [H]

Synonym: Pcryo_2078

Alternate gene names: 93006902

Gene position: 2545324-2544758 (Counterclockwise)

Preceding gene: 93006905

Following gene: 93006898

Centisome position: 83.18

GC content: 42.33

Gene sequence:

>567_bases
ATGGCGTCTATTATCAATCAAGAAATCCCAGAATTTTCAGCAGATGCGTTTGTAAATGGTGAATTTAAAACCATTACTTC
AGAAGACGTAAAAGGCAGCTGGGCAATTTTCCTATTTTACCCAGCCGATTTTACCTTTGTTTGCCCAACTGAACTTGAAG
ACATGGCAGGTCATTACGACGAGTTAAAAGGTTTAGGCGTAGAAGTGTACTCAGTATCAACGGATACACATTTCACCCAT
AAAGCATGGCATGATTCTTCAGAAGCAATCGGTAAAGTAACTTACCCAATGATTGGTGATCCTACTGGCCGTATCACTCG
TGGCTTTAATGTCATGATTGAAGAAGCTGGTCTAGCTGAGCGCGGTACATTCTTAGTAGATCCAGACGGCTTAATTCAAG
TTGCTGAAATCCATGCTGGCGGTATTGGCCGTAGTGCAAAAGATATGCTACGTAAAGTAAAAGCGGCACAATATGTTCGT
GAAAACGACGGCGAAGTTTGCCCAGCCGCTTGGGAAGCTGGTCAAGAGACTTTAAAACCAAGTCTTGATCTGGTTGGTAA
AATCTAA

Upstream 100 bases:

>100_bases
GTTTGTCAGGTAGCCCCGATAGTGTAAGGGTTAATAGATGCAAATCTATAAATAAATTTCAATTAACGAAACTTTAATCA
ATCAAAAAAAGGAGCCACTC

Downstream 100 bases:

>100_bases
GTAACTATTGCTTGGATAGTGTGACAGAAGGCAGTATCTGCTTATTCATCATACTAAATAAAGTATAAAAAACCCCATTA
ATGAACTGACCCCCAAATGT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MASIINQEIPEFSADAFVNGEFKTITSEDVKGSWAIFLFYPADFTFVCPTELEDMAGHYDELKGLGVEVYSVSTDTHFTH
KAWHDSSEAIGKVTYPMIGDPTGRITRGFNVMIEEAGLAERGTFLVDPDGLIQVAEIHAGGIGRSAKDMLRKVKAAQYVR
ENDGEVCPAAWEAGQETLKPSLDLVGKI

Sequences:

>Translated_188_residues
MASIINQEIPEFSADAFVNGEFKTITSEDVKGSWAIFLFYPADFTFVCPTELEDMAGHYDELKGLGVEVYSVSTDTHFTH
KAWHDSSEAIGKVTYPMIGDPTGRITRGFNVMIEEAGLAERGTFLVDPDGLIQVAEIHAGGIGRSAKDMLRKVKAAQYVR
ENDGEVCPAAWEAGQETLKPSLDLVGKI
>Mature_187_residues
ASIINQEIPEFSADAFVNGEFKTITSEDVKGSWAIFLFYPADFTFVCPTELEDMAGHYDELKGLGVEVYSVSTDTHFTHK
AWHDSSEAIGKVTYPMIGDPTGRITRGFNVMIEEAGLAERGTFLVDPDGLIQVAEIHAGGIGRSAKDMLRKVKAAQYVRE
NDGEVCPAAWEAGQETLKPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=183, Percent_Identity=42.0765027322404, Blast_Score=160, Evalue=7e-40,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=41.8994413407821, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=39.010989010989, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=36.8131868131868, Blast_Score=140, Evalue=7e-34,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=36.8131868131868, Blast_Score=140, Evalue=7e-34,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=36.8131868131868, Blast_Score=140, Evalue=7e-34,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=36.3636363636364, Blast_Score=140, Evalue=8e-34,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=44.4444444444444, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=65.0537634408602, Blast_Score=261, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17554494, Length=178, Percent_Identity=39.3258426966292, Blast_Score=149, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=37.7049180327869, Blast_Score=143, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=37.7049180327869, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=186, Percent_Identity=32.258064516129, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320661, Length=185, Percent_Identity=32.4324324324324, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319407, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17738015, Length=184, Percent_Identity=36.4130434782609, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=38.1720430107527, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=36.8131868131868, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=36.8131868131868, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17157991, Length=177, Percent_Identity=37.2881355932203, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24641739, Length=177, Percent_Identity=37.2881355932203, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24581278, Length=183, Percent_Identity=28.4153005464481, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17975518, Length=185, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652436, Length=185, Percent_Identity=27.027027027027, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652434, Length=185, Percent_Identity=27.027027027027, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20562; Mature: 20431

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIINQEIPEFSADAFVNGEFKTITSEDVKGSWAIFLFYPADFTFVCPTELEDMAGHYD
CCCCHHHCCCCCCCCEEECCCEEEEECCCCCCCEEEEEEECCCEEEECCCCHHHHCCCHH
ELKGLGVEVYSVSTDTHFTHKAWHDSSEAIGKVTYPMIGDPTGRITRGFNVMIEEAGLAE
HHCCCCEEEEEEECCCCEEHHHHCCCCHHCCEEECCCCCCCCCCEECCEEEEEECCCCCC
RGTFLVDPDGLIQVAEIHAGGIGRSAKDMLRKVKAAQYVRENDGEVCPAAWEAGQETLKP
CCCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHCC
SLDLVGKI
CHHHHCCC
>Mature Secondary Structure 
ASIINQEIPEFSADAFVNGEFKTITSEDVKGSWAIFLFYPADFTFVCPTELEDMAGHYD
CCCHHHCCCCCCCCEEECCCEEEEECCCCCCCEEEEEEECCCEEEECCCCHHHHCCCHH
ELKGLGVEVYSVSTDTHFTHKAWHDSSEAIGKVTYPMIGDPTGRITRGFNVMIEEAGLAE
HHCCCCEEEEEEECCCCEEHHHHCCCCHHCCEEECCCCCCCCCCEECCEEEEEECCCCCC
RGTFLVDPDGLIQVAEIHAGGIGRSAKDMLRKVKAAQYVRENDGEVCPAAWEAGQETLKP
CCCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHCC
SLDLVGKI
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 8180695; 8012595 [H]