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The map label for this gene is ftsA [H]

Identifier: 93006852

GI number: 93006852

Start: 2492254

End: 2493594

Strand: Reverse

Name: ftsA [H]

Synonym: Pcryo_2028

Alternate gene names: 93006852

Gene position: 2493594-2492254 (Counterclockwise)

Preceding gene: 93006853

Following gene: 93006851

Centisome position: 81.49

GC content: 41.09

Gene sequence:

>1341_bases
ATGGAGACATCATTTGTTCTCCTGTTTAGCGATAATTTGTCTGGTACCATGAAAAATACTGAAAATTTGGTTGTTGTCCA
TTTAAGTGCCACGGCAGTTTATGTCGTCATTGGTAGTGTTGTGTCTGCAAAAGACATCCGTATTATGGGTGTGGGACAAG
TTAGAAATAGCGACTTTTATCAAGGTCAAATCAAGCATCGCGAACGCTTGCAAGGCGCTATCAAACAGGCTATTCAAGAA
GCGGAAGATACCGCTAATTGCCGTGTGCATAGTGTCTGGCTTACGCTGGCAACTCCTGAGCTATTGAGCAAAAATAGTGC
GGGCGATGTTAGAGTAGAAGATGAATTCGTTCGTGCTAAAGATATGGTGCAAGCACTCTCAAATGCCAAATCGCAAGATT
TGTCATCTGACTATTATTTGATGCATTGTTGTCAGCAAGGTATTTATATCGATAACCAAGAGTTTATGGTTGATGATGCC
ATTGATATGGTGGCGCACAATATAGCTGTGATGTATCACATGATGATGATGCCAGTTGCTGGTCGTCAAAATATACAAAA
ACTATTGCAAAGCTGTGATGTGGGTATTGATCATATTGTCTTCGATGCGGTAACCAGTGCCGAATATAGCTTGATGAGCG
AAGAGCGCCAACAAGGCGTTTGCTTGGTAGATATAGGTGCTAGCACCACAAGTATTTGCGTTTATAAAGAAAATAAGCTG
ATTTTTACCCATTGTATCGCAACGGGTAGTCATGAAGTGACGATGGATATTTCAGCAGACGTTGGTATTTCGATGATAGA
GGCTGAAAAGCTGAAAAAATCGCATGGTACAGTGGATGTGAACAGCGTAGATCCAAGCTCATTTTTCCTATTTAAACCGC
AAGGGTCAGGTGATGAAATCAACATTGGTATCTATAACCTTGCGCGTATTATCGAAGCCCGTTACGTGCAGATTTTCACT
GAAGTAGTACGCCAGTTACATGAAGCGGACTTATTAGGCTATATTGATAAGGGCATTGTGCTCACAGGCGGCGGTAGTGC
GATTAAAGGCATGATACCGTTTGCGAAAAAACTATTAAAAATGCCAGTGGTATTAACCAATACGCATCCTGCGATTAGTG
CTTATAATCATTTTGATAATGATGAATCATTTAAGCAGCTGAATCTTCAGGTTAATGATCGGGCTTATCAAACGGCATTT
GGTACACTACTATATAGCCAAAGCGAGCAGTTTCGGCGCAGTGAAAAAAGCGAGCCTGAAGCGATTCAAAAAAATCGTGT
GACGGGTGTTTTTCAAAGTGCTGGTCAACGTTTTGCCAGTGTACTAAAAAAGATATTATAA

Upstream 100 bases:

>100_bases
TATATAAAGTAGCCAACACGCTAAACTTGTCTGCTTTATTTTTTATACAGAGTATACATACGCTATTATCAGCTGATAAT
AGACTTATTTTAATGATTTA

Downstream 100 bases:

>100_bases
TTGTCCTATAATCCTGCTGACAATCTACTTACCGTAATTAGATAAGCGGTTTGTCAGCAAGACCAAGCAAGCATATTAAA
AGCAATACCCTGTATAATAA

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
METSFVLLFSDNLSGTMKNTENLVVVHLSATAVYVVIGSVVSAKDIRIMGVGQVRNSDFYQGQIKHRERLQGAIKQAIQE
AEDTANCRVHSVWLTLATPELLSKNSAGDVRVEDEFVRAKDMVQALSNAKSQDLSSDYYLMHCCQQGIYIDNQEFMVDDA
IDMVAHNIAVMYHMMMMPVAGRQNIQKLLQSCDVGIDHIVFDAVTSAEYSLMSEERQQGVCLVDIGASTTSICVYKENKL
IFTHCIATGSHEVTMDISADVGISMIEAEKLKKSHGTVDVNSVDPSSFFLFKPQGSGDEINIGIYNLARIIEARYVQIFT
EVVRQLHEADLLGYIDKGIVLTGGGSAIKGMIPFAKKLLKMPVVLTNTHPAISAYNHFDNDESFKQLNLQVNDRAYQTAF
GTLLYSQSEQFRRSEKSEPEAIQKNRVTGVFQSAGQRFASVLKKIL

Sequences:

>Translated_446_residues
METSFVLLFSDNLSGTMKNTENLVVVHLSATAVYVVIGSVVSAKDIRIMGVGQVRNSDFYQGQIKHRERLQGAIKQAIQE
AEDTANCRVHSVWLTLATPELLSKNSAGDVRVEDEFVRAKDMVQALSNAKSQDLSSDYYLMHCCQQGIYIDNQEFMVDDA
IDMVAHNIAVMYHMMMMPVAGRQNIQKLLQSCDVGIDHIVFDAVTSAEYSLMSEERQQGVCLVDIGASTTSICVYKENKL
IFTHCIATGSHEVTMDISADVGISMIEAEKLKKSHGTVDVNSVDPSSFFLFKPQGSGDEINIGIYNLARIIEARYVQIFT
EVVRQLHEADLLGYIDKGIVLTGGGSAIKGMIPFAKKLLKMPVVLTNTHPAISAYNHFDNDESFKQLNLQVNDRAYQTAF
GTLLYSQSEQFRRSEKSEPEAIQKNRVTGVFQSAGQRFASVLKKIL
>Mature_446_residues
METSFVLLFSDNLSGTMKNTENLVVVHLSATAVYVVIGSVVSAKDIRIMGVGQVRNSDFYQGQIKHRERLQGAIKQAIQE
AEDTANCRVHSVWLTLATPELLSKNSAGDVRVEDEFVRAKDMVQALSNAKSQDLSSDYYLMHCCQQGIYIDNQEFMVDDA
IDMVAHNIAVMYHMMMMPVAGRQNIQKLLQSCDVGIDHIVFDAVTSAEYSLMSEERQQGVCLVDIGASTTSICVYKENKL
IFTHCIATGSHEVTMDISADVGISMIEAEKLKKSHGTVDVNSVDPSSFFLFKPQGSGDEINIGIYNLARIIEARYVQIFT
EVVRQLHEADLLGYIDKGIVLTGGGSAIKGMIPFAKKLLKMPVVLTNTHPAISAYNHFDNDESFKQLNLQVNDRAYQTAF
GTLLYSQSEQFRRSEKSEPEAIQKNRVTGVFQSAGQRFASVLKKIL

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=437, Percent_Identity=26.5446224256293, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 49506; Mature: 49506

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSFVLLFSDNLSGTMKNTENLVVVHLSATAVYVVIGSVVSAKDIRIMGVGQVRNSDFY
CCCEEEEEEECCCCCCCCCCCCEEEEEECHHEEEHHHHHHHCCCCEEEEEECCCCCCCCC
QGQIKHRERLQGAIKQAIQEAEDTANCRVHSVWLTLATPELLSKNSAGDVRVEDEFVRAK
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHCCCCCCCEEEHHHHHHHH
DMVQALSNAKSQDLSSDYYLMHCCQQGIYIDNQEFMVDDAIDMVAHNIAVMYHMMMMPVA
HHHHHHHCCCCCCCCCCHHHHHHHHCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCC
GRQNIQKLLQSCDVGIDHIVFDAVTSAEYSLMSEERQQGVCLVDIGASTTSICVYKENKL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCE
IFTHCIATGSHEVTMDISADVGISMIEAEKLKKSHGTVDVNSVDPSSFFLFKPQGSGDEI
EEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCCCEEEECCCCCCCEE
NIGIYNLARIIEARYVQIFTEVVRQLHEADLLGYIDKGIVLTGGGSAIKGMIPFAKKLLK
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHH
MPVVLTNTHPAISAYNHFDNDESFKQLNLQVNDRAYQTAFGTLLYSQSEQFRRSEKSEPE
CCEEEECCCCCHHHHCCCCCCCCHHEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCH
AIQKNRVTGVFQSAGQRFASVLKKIL
HHHHHCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
METSFVLLFSDNLSGTMKNTENLVVVHLSATAVYVVIGSVVSAKDIRIMGVGQVRNSDFY
CCCEEEEEEECCCCCCCCCCCCEEEEEECHHEEEHHHHHHHCCCCEEEEEECCCCCCCCC
QGQIKHRERLQGAIKQAIQEAEDTANCRVHSVWLTLATPELLSKNSAGDVRVEDEFVRAK
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHCCCCCCCEEEHHHHHHHH
DMVQALSNAKSQDLSSDYYLMHCCQQGIYIDNQEFMVDDAIDMVAHNIAVMYHMMMMPVA
HHHHHHHCCCCCCCCCCHHHHHHHHCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCC
GRQNIQKLLQSCDVGIDHIVFDAVTSAEYSLMSEERQQGVCLVDIGASTTSICVYKENKL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCE
IFTHCIATGSHEVTMDISADVGISMIEAEKLKKSHGTVDVNSVDPSSFFLFKPQGSGDEI
EEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCCCEEEECCCCCCCEE
NIGIYNLARIIEARYVQIFTEVVRQLHEADLLGYIDKGIVLTGGGSAIKGMIPFAKKLLK
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHH
MPVVLTNTHPAISAYNHFDNDESFKQLNLQVNDRAYQTAFGTLLYSQSEQFRRSEKSEPE
CCEEEECCCCCHHHHCCCCCCCCHHEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCH
AIQKNRVTGVFQSAGQRFASVLKKIL
HHHHHCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]