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The map label for this gene is ispH [H]

Identifier: 93006826

GI number: 93006826

Start: 2462228

End: 2463184

Strand: Reverse

Name: ispH [H]

Synonym: Pcryo_2002

Alternate gene names: 93006826

Gene position: 2463184-2462228 (Counterclockwise)

Preceding gene: 93006833

Following gene: 93006825

Centisome position: 80.5

GC content: 46.19

Gene sequence:

>957_bases
ATGCAAATTTATCTTGCCAATCCACGTGGATTTTGTGCTGGTGTGGATCGCGCGATTGCGATTGTCAACGAAGCACTGTT
ACGTTTTGAGCCACCCATTTATGTTCGTCATGAAGTGGTACATAACAAGTTTGTGGTATCCGACTTGGCCAATCGCGGTG
CTGTTTTTGTGGAAGAGCTACATGAAGTGCCAGACGGCTCTATTGTTATTTTTTCCGCTCACGGGGTTTCAAAAGCTGTA
GAAGATGAAGCAGAACGTCGTGATTTGACGGTGTTTGATGCCACTTGTCCTTTGGTCACTAAAGTACATATCGAAGTCGC
TAAATTTGCGCAGGATGGTATGGATGCGGTATTGATTGGACATGCGGGACATCCTGAAGTAGAAGGCACTATGGGACGCT
TTAACCATCGTCATGGCGGACAGATTCATCTGGTTGAAAACGAGAGCGATGTTGAAGCTTTGAGCGTACAAGATGCTGAG
CGCTTAGCATTTGTGACCCAAACGACCTTATCGATGGATGATACCGCGCGCGTTATTGATGCGCTACGTGAAAAATTCCC
AAGCATTCAAGGTCCACGTAAAGACGATATCTGTTATGCCACCCAAAATCGTCAAGATGCGGTCAAGGATTTAGCGGGTC
GCTGTGAGGTGGTCTTGGTCGTTGGCTCACCAAACTCATCAAACTCAAATCGTTTGCGTGAATTGGCAGAGCGCATGAAT
TGCCGCGCGTATTTGATTGATAATGCCACTGAAATGAATAAGAGCTGGTTCGATGGGATACAAAGTGTGGGCGTGACTGC
AGGTGCTTCAGCGCCTGAAGTATTGATTCAAGAGGTACTACAGCAGCTGCAAAATTGGGGTGGTGATTTGCCAAGTGAGC
TGTTGGGTATTGAAGAAAATGTCACCTTTAGCTTGCCAAAAGCTTTACGAATTCCAATGACGCAAGTTGGCAAATAA

Upstream 100 bases:

>100_bases
AGTAGGGTATCGTTTTTATCCCAACTTTTGAATAAAAGTTTCGGTGGCTTAAGCTTTAAGCCTAGGCTTTTATATAAATT
ATCTAATGATAGGTCTTCTT

Downstream 100 bases:

>100_bases
AATAAGCAGGCTTTGTATATAGCGCCAGATAGGTCACATAAAATGAAAAAGCAGAAAAAAAGATTTGTCTTGGCAGAAGC
TAGCCTTGATGAGATCAATA

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MQIYLANPRGFCAGVDRAIAIVNEALLRFEPPIYVRHEVVHNKFVVSDLANRGAVFVEELHEVPDGSIVIFSAHGVSKAV
EDEAERRDLTVFDATCPLVTKVHIEVAKFAQDGMDAVLIGHAGHPEVEGTMGRFNHRHGGQIHLVENESDVEALSVQDAE
RLAFVTQTTLSMDDTARVIDALREKFPSIQGPRKDDICYATQNRQDAVKDLAGRCEVVLVVGSPNSSNSNRLRELAERMN
CRAYLIDNATEMNKSWFDGIQSVGVTAGASAPEVLIQEVLQQLQNWGGDLPSELLGIEENVTFSLPKALRIPMTQVGK

Sequences:

>Translated_318_residues
MQIYLANPRGFCAGVDRAIAIVNEALLRFEPPIYVRHEVVHNKFVVSDLANRGAVFVEELHEVPDGSIVIFSAHGVSKAV
EDEAERRDLTVFDATCPLVTKVHIEVAKFAQDGMDAVLIGHAGHPEVEGTMGRFNHRHGGQIHLVENESDVEALSVQDAE
RLAFVTQTTLSMDDTARVIDALREKFPSIQGPRKDDICYATQNRQDAVKDLAGRCEVVLVVGSPNSSNSNRLRELAERMN
CRAYLIDNATEMNKSWFDGIQSVGVTAGASAPEVLIQEVLQQLQNWGGDLPSELLGIEENVTFSLPKALRIPMTQVGK
>Mature_318_residues
MQIYLANPRGFCAGVDRAIAIVNEALLRFEPPIYVRHEVVHNKFVVSDLANRGAVFVEELHEVPDGSIVIFSAHGVSKAV
EDEAERRDLTVFDATCPLVTKVHIEVAKFAQDGMDAVLIGHAGHPEVEGTMGRFNHRHGGQIHLVENESDVEALSVQDAE
RLAFVTQTTLSMDDTARVIDALREKFPSIQGPRKDDICYATQNRQDAVKDLAGRCEVVLVVGSPNSSNSNRLRELAERMN
CRAYLIDNATEMNKSWFDGIQSVGVTAGASAPEVLIQEVLQQLQNWGGDLPSELLGIEENVTFSLPKALRIPMTQVGK

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=316, Percent_Identity=62.9746835443038, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34965; Mature: 34965

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIYLANPRGFCAGVDRAIAIVNEALLRFEPPIYVRHEVVHNKFVVSDLANRGAVFVEEL
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHH
HEVPDGSIVIFSAHGVSKAVEDEAERRDLTVFDATCPLVTKVHIEVAKFAQDGMDAVLIG
HHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHHHHCCCCEEEEE
HAGHPEVEGTMGRFNHRHGGQIHLVENESDVEALSVQDAERLAFVTQTTLSMDDTARVID
CCCCCCCCCCHHHCCCCCCCEEEEEECCCCCHHEECCCHHHHHHHHHHHCCCCHHHHHHH
ALREKFPSIQGPRKDDICYATQNRQDAVKDLAGRCEVVLVVGSPNSSNSNRLRELAERMN
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCC
CRAYLIDNATEMNKSWFDGIQSVGVTAGASAPEVLIQEVLQQLQNWGGDLPSELLGIEEN
CEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
VTFSLPKALRIPMTQVGK
CEEECCHHHCCCHHHCCC
>Mature Secondary Structure
MQIYLANPRGFCAGVDRAIAIVNEALLRFEPPIYVRHEVVHNKFVVSDLANRGAVFVEEL
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHH
HEVPDGSIVIFSAHGVSKAVEDEAERRDLTVFDATCPLVTKVHIEVAKFAQDGMDAVLIG
HHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHHHHCCCCEEEEE
HAGHPEVEGTMGRFNHRHGGQIHLVENESDVEALSVQDAERLAFVTQTTLSMDDTARVID
CCCCCCCCCCHHHCCCCCCCEEEEEECCCCCHHEECCCHHHHHHHHHHHCCCCHHHHHHH
ALREKFPSIQGPRKDDICYATQNRQDAVKDLAGRCEVVLVVGSPNSSNSNRLRELAERMN
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCC
CRAYLIDNATEMNKSWFDGIQSVGVTAGASAPEVLIQEVLQQLQNWGGDLPSELLGIEEN
CEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
VTFSLPKALRIPMTQVGK
CEEECCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA