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The map label for this gene is rpe [H]

Identifier: 93006818

GI number: 93006818

Start: 2452783

End: 2453472

Strand: Reverse

Name: rpe [H]

Synonym: Pcryo_1994

Alternate gene names: 93006818

Gene position: 2453472-2452783 (Counterclockwise)

Preceding gene: 93006819

Following gene: 93006817

Centisome position: 80.18

GC content: 45.07

Gene sequence:

>690_bases
ATGATCAGTCCCTCTAAGCCGTATCTAATCGCCCCTTCCATATTATCTGCTGACTTTGCCAAATTAGGCGAAGAAGTAGA
ACGTGTATTGGCGTCTGGTGCTGATGTCATCCATTTTGATGTGATGGACAACCATTATGTACCCAATTTGACGTTTGGTA
GCATGATTTGTAAGGCACTGCGTGATTATGGGATTGATGCACCAATTGACGTGCATCTAATGGTTAGCCCTGTTGATAGT
ATGATTGAGCAGTTCTTAGAGGCAGGTGCCAGCATCATCACATTTCATCCGGAAGCAAGCTCGCATATCGATCGCTCTTT
GCAGTTGATTAAAGATGGCGGCGCTGAGTGTGGTTTGGTATTGAATCCAGCAACACCATTGCATTATTTAGACTATGTCA
TGGATAAAGTGGATCAGGTCCTACTGATGAGTGTCAATCCTGGCTACGGTGGTCAGTCATTTATTGAAGGGACGCTAGAA
AAGGTTCGCCAAGTACGTCAGCGTATCATTACTAGCGGTCGTGATATTAGATTAGAAGTAGATGGCGGTATCAAAGCCAG
TAATATCCGCGCCATTGCCGAAGCAGGTGCTGATATGTTCGTCGCCGGTTCAGCGATATTTAATCAAGAAGATTATAAAG
CAGCAATCGATGCCATGCGTGCAGAGCTTGCCTTGGCAAATGGGGAGTAA

Upstream 100 bases:

>100_bases
AGACCCTGATTATCCGTTATAATAGACATACGTATTATTCGTGCTATGCATACATCTATATATTAAATCCTTAGTCAAAT
ATCCATTAGGTAGCTCAATT

Downstream 100 bases:

>100_bases
CGCCCCATATAGTAAGTTATTTACTATTAAATAGTAAAGTTACCTATTATTAATAGCCGCTGTATGACTGAGTATATTAA
GCGACATGTCAGCTAAAGGT

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MISPSKPYLIAPSILSADFAKLGEEVERVLASGADVIHFDVMDNHYVPNLTFGSMICKALRDYGIDAPIDVHLMVSPVDS
MIEQFLEAGASIITFHPEASSHIDRSLQLIKDGGAECGLVLNPATPLHYLDYVMDKVDQVLLMSVNPGYGGQSFIEGTLE
KVRQVRQRIITSGRDIRLEVDGGIKASNIRAIAEAGADMFVAGSAIFNQEDYKAAIDAMRAELALANGE

Sequences:

>Translated_229_residues
MISPSKPYLIAPSILSADFAKLGEEVERVLASGADVIHFDVMDNHYVPNLTFGSMICKALRDYGIDAPIDVHLMVSPVDS
MIEQFLEAGASIITFHPEASSHIDRSLQLIKDGGAECGLVLNPATPLHYLDYVMDKVDQVLLMSVNPGYGGQSFIEGTLE
KVRQVRQRIITSGRDIRLEVDGGIKASNIRAIAEAGADMFVAGSAIFNQEDYKAAIDAMRAELALANGE
>Mature_229_residues
MISPSKPYLIAPSILSADFAKLGEEVERVLASGADVIHFDVMDNHYVPNLTFGSMICKALRDYGIDAPIDVHLMVSPVDS
MIEQFLEAGASIITFHPEASSHIDRSLQLIKDGGAECGLVLNPATPLHYLDYVMDKVDQVLLMSVNPGYGGQSFIEGTLE
KVRQVRQRIITSGRDIRLEVDGGIKASNIRAIAEAGADMFVAGSAIFNQEDYKAAIDAMRAELALANGE

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=41.0377358490566, Blast_Score=169, Evalue=1e-42,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=38.6792452830189, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=32.1428571428571, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1789788, Length=224, Percent_Identity=71.875, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1790523, Length=223, Percent_Identity=34.9775784753363, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790754, Length=208, Percent_Identity=29.8076923076923, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=219, Percent_Identity=39.2694063926941, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6322341, Length=236, Percent_Identity=35.1694915254237, Blast_Score=147, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=37.914691943128, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24796; Mature: 24796

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPSKPYLIAPSILSADFAKLGEEVERVLASGADVIHFDVMDNHYVPNLTFGSMICKAL
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHH
RDYGIDAPIDVHLMVSPVDSMIEQFLEAGASIITFHPEASSHIDRSLQLIKDGGAECGLV
HHCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEE
LNPATPLHYLDYVMDKVDQVLLMSVNPGYGGQSFIEGTLEKVRQVRQRIITSGRDIRLEV
ECCCCHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DGGIKASNIRAIAEAGADMFVAGSAIFNQEDYKAAIDAMRAELALANGE
CCCEEHHHHHHHHHCCCCEEEECHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISPSKPYLIAPSILSADFAKLGEEVERVLASGADVIHFDVMDNHYVPNLTFGSMICKAL
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHH
RDYGIDAPIDVHLMVSPVDSMIEQFLEAGASIITFHPEASSHIDRSLQLIKDGGAECGLV
HHCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEE
LNPATPLHYLDYVMDKVDQVLLMSVNPGYGGQSFIEGTLEKVRQVRQRIITSGRDIRLEV
ECCCCHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DGGIKASNIRAIAEAGADMFVAGSAIFNQEDYKAAIDAMRAELALANGE
CCCEEHHHHHHHHHCCCCEEEECHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]