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The map label for this gene is ubiA [H]

Identifier: 93006804

GI number: 93006804

Start: 2440213

End: 2441136

Strand: Reverse

Name: ubiA [H]

Synonym: Pcryo_1980

Alternate gene names: 93006804

Gene position: 2441136-2440213 (Counterclockwise)

Preceding gene: 93006805

Following gene: 93006803

Centisome position: 79.78

GC content: 43.07

Gene sequence:

>924_bases
ATGACATTTAACGACAAGCTACAAGCTTATATTCAGCTGACACGTTTTGATAAGCCAGTAGGTATTGAACTGCTACTATG
GCCAACATTATGGGGTGTATTATTCGCTGCGATGGGGCAGGCGCAGCAACAAGGTGCAGGCATTACGGCAGGGCTACCCA
GTTTAAGTATCTTTGTGATTTTTGCCCTTGGAGCGATATTGATGCGGGCAGCAGGCTGTGCGATTAATGATTTTGCTGAC
CGTAAAGTCGATGGTCACGTAAGCCGTACTAAAGGTCGTCCGTTAGCTGATGGACGTCTGTCTGCTAAAGAGGCCATTGC
AGCTTTTTTAGTATTAGTATTATTAAGTGCAAGTTTGCTTCTGTTTTTACCCATTCAAGTATTCTATTGGTCGTTTGGTG
CCGTCATATTGGCGTTTATTTATCCATTTATGAAACGTTATACGCATTTGCCGCAAGTGTTTTTGGCAGCGGCTTTCGGC
TGGGCGATACCGATGGCATATGTCGCGATACAAGGCGCGCCTGATATCTGGTGTTGGTTGTTATTCCTTGCTTATATGTG
TTGGACAGTTGCTTATGATACTCAATATGCAATGGCTGACCGAGAGGATGATATAAAGATAGGGGTTAAATCAACCGCGA
TATTATTTGATCGTTATGATGTGATTATCATCTCGTTACTACAGACGTTGTTTTTAGTTATCATGGGCGCAGTCATGTGG
CATTATTTTGCGCCGACCAGTTTAGGTATTACGCCAGTCTTTGGCTTGGCGTTAGTCGCGATGATGTTTGCTAAGCAAAA
CAGTGCGTGTGCCAGTCGTAATGCTTTGGCTTGTTTTAAAGCATTTTTAGCCAATATATGGGTAGGACGTTACGTTTTTG
TTCTTATAGCCATCGCTTGTATCTGGACGACTTTTAATGGATAA

Upstream 100 bases:

>100_bases
TATATTGAACTCACTATAGCGTACGCCAAGTTCTATGTACTAAATTGCTATACACCCAAATCATTATTTACTATTTTCTA
TCCATGATAATTAAAACGCC

Downstream 100 bases:

>100_bases
GCTCAATAAATTTTCGAGACTAAAGACCAAGAAATCATCTGCGCATAGTGCTTCTAAGATAGATTATGAGGCAAGATTGG
CTGAGAATGGTTTGACGCGT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTFNDKLQAYIQLTRFDKPVGIELLLWPTLWGVLFAAMGQAQQQGAGITAGLPSLSIFVIFALGAILMRAAGCAINDFAD
RKVDGHVSRTKGRPLADGRLSAKEAIAAFLVLVLLSASLLLFLPIQVFYWSFGAVILAFIYPFMKRYTHLPQVFLAAAFG
WAIPMAYVAIQGAPDIWCWLLFLAYMCWTVAYDTQYAMADREDDIKIGVKSTAILFDRYDVIIISLLQTLFLVIMGAVMW
HYFAPTSLGITPVFGLALVAMMFAKQNSACASRNALACFKAFLANIWVGRYVFVLIAIACIWTTFNG

Sequences:

>Translated_307_residues
MTFNDKLQAYIQLTRFDKPVGIELLLWPTLWGVLFAAMGQAQQQGAGITAGLPSLSIFVIFALGAILMRAAGCAINDFAD
RKVDGHVSRTKGRPLADGRLSAKEAIAAFLVLVLLSASLLLFLPIQVFYWSFGAVILAFIYPFMKRYTHLPQVFLAAAFG
WAIPMAYVAIQGAPDIWCWLLFLAYMCWTVAYDTQYAMADREDDIKIGVKSTAILFDRYDVIIISLLQTLFLVIMGAVMW
HYFAPTSLGITPVFGLALVAMMFAKQNSACASRNALACFKAFLANIWVGRYVFVLIAIACIWTTFNG
>Mature_306_residues
TFNDKLQAYIQLTRFDKPVGIELLLWPTLWGVLFAAMGQAQQQGAGITAGLPSLSIFVIFALGAILMRAAGCAINDFADR
KVDGHVSRTKGRPLADGRLSAKEAIAAFLVLVLLSASLLLFLPIQVFYWSFGAVILAFIYPFMKRYTHLPQVFLAAAFGW
AIPMAYVAIQGAPDIWCWLLFLAYMCWTVAYDTQYAMADREDDIKIGVKSTAILFDRYDVIIISLLQTLFLVIMGAVMWH
YFAPTSLGITPVFGLALVAMMFAKQNSACASRNALACFKAFLANIWVGRYVFVLIAIACIWTTFNG

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=298, Percent_Identity=31.8791946308725, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1790473, Length=296, Percent_Identity=48.6486486486487, Blast_Score=259, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17553718, Length=302, Percent_Identity=33.7748344370861, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32565247, Length=213, Percent_Identity=40.8450704225352, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17553720, Length=270, Percent_Identity=32.5925925925926, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=154, Percent_Identity=40.2597402597403, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32565243, Length=153, Percent_Identity=40.5228758169935, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=304, Percent_Identity=34.5394736842105, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI21355567, Length=308, Percent_Identity=35.3896103896104, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33979; Mature: 33848

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFNDKLQAYIQLTRFDKPVGIELLLWPTLWGVLFAAMGQAQQQGAGITAGLPSLSIFVI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FALGAILMRAAGCAINDFADRKVDGHVSRTKGRPLADGRLSAKEAIAAFLVLVLLSASLL
HHHHHHHHHHCCCCHHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LFLPIQVFYWSFGAVILAFIYPFMKRYTHLPQVFLAAAFGWAIPMAYVAIQGAPDIWCWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LFLAYMCWTVAYDTQYAMADREDDIKIGVKSTAILFDRYDVIIISLLQTLFLVIMGAVMW
HHHHHHHHHHHHCCHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYFAPTSLGITPVFGLALVAMMFAKQNSACASRNALACFKAFLANIWVGRYVFVLIAIAC
HHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWTTFNG
HHHHCCC
>Mature Secondary Structure 
TFNDKLQAYIQLTRFDKPVGIELLLWPTLWGVLFAAMGQAQQQGAGITAGLPSLSIFVI
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH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HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA