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The map label for this gene is exbB [H]

Identifier: 93006729

GI number: 93006729

Start: 2352970

End: 2353686

Strand: Reverse

Name: exbB [H]

Synonym: Pcryo_1905

Alternate gene names: 93006729

Gene position: 2353686-2352970 (Counterclockwise)

Preceding gene: 93006730

Following gene: 93006728

Centisome position: 76.92

GC content: 46.86

Gene sequence:

>717_bases
ATGGCACAACTTACTAGGGAGTCTGACATGGACTTTACAACTTACTGGCAATATAGCGATATGGTGACTAGAACCTTGTT
CTTTTTACTGCTCGCTTTATCTATCATCTCTTGGGTCACGGGCATCATTCGGGTGCTACAAAGCCGAAAATTGGTGACGA
CTGTTGCTGATGATTTGAGCCAGCAGATGCAGGAAAAACGCTCAGATCTAAGTGTGGCAGATGCAGCGACGCGGCGTTTG
ATTACTGAGCAAACCTTGCTAAAGCACATTGGTCGCTACCGTTTTGCTAGCGAGCGTGGTTTGCCTATCCTTGGTACGAC
AGCAGCGATTGCACCGTTTATTGGTCTGTTTGGGACAGTATGGGGTATTTTCCATGCCCTACGTAATATTGGTATGAGCG
GACAAGCAGGACTTGGGCAGGTAGCGGGACCGGTCGGTGAGGCACTTATCATGACCGGTTTAGGAATAGCCGTAGCGATT
CCAGCGGTAGTGTTCTATAACCTTGCTGTACGTATTAATCGTAGCATCATGTACCAGGCAAATGATCGCGCCCATGATTT
ACTGGCGCAATCTGCTGAGCTAGCAGTCACACAACAATCATCAATAAATAATGAACCTGCCGTGACTCAAGCTCAGTTAG
TAAAAGGTAATCATACAGAGACGCAAGCCCCTCAACAAACAGAACATTATCATAAATCAGCACCATCACAGCCGTAA

Upstream 100 bases:

>100_bases
GTGAGCTACGCAGTACCTTAATGATTATCCATCTATAAAAACATACATTCTAATCTTTTCACGATAAGCATAAATGCGAT
AGTCGCTGCAGGTTTATGTG

Downstream 100 bases:

>100_bases
CCCTATTTATTGATAGGGTTTTACATTAAAAGAAAGCGAAGCGACAGATAAGCTAGAAAGTAATAGCTTTGATGATTATA
CAAAACGTATTGAGAATATT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAQLTRESDMDFTTYWQYSDMVTRTLFFLLLALSIISWVTGIIRVLQSRKLVTTVADDLSQQMQEKRSDLSVADAATRRL
ITEQTLLKHIGRYRFASERGLPILGTTAAIAPFIGLFGTVWGIFHALRNIGMSGQAGLGQVAGPVGEALIMTGLGIAVAI
PAVVFYNLAVRINRSIMYQANDRAHDLLAQSAELAVTQQSSINNEPAVTQAQLVKGNHTETQAPQQTEHYHKSAPSQP

Sequences:

>Translated_238_residues
MAQLTRESDMDFTTYWQYSDMVTRTLFFLLLALSIISWVTGIIRVLQSRKLVTTVADDLSQQMQEKRSDLSVADAATRRL
ITEQTLLKHIGRYRFASERGLPILGTTAAIAPFIGLFGTVWGIFHALRNIGMSGQAGLGQVAGPVGEALIMTGLGIAVAI
PAVVFYNLAVRINRSIMYQANDRAHDLLAQSAELAVTQQSSINNEPAVTQAQLVKGNHTETQAPQQTEHYHKSAPSQP
>Mature_237_residues
AQLTRESDMDFTTYWQYSDMVTRTLFFLLLALSIISWVTGIIRVLQSRKLVTTVADDLSQQMQEKRSDLSVADAATRRLI
TEQTLLKHIGRYRFASERGLPILGTTAAIAPFIGLFGTVWGIFHALRNIGMSGQAGLGQVAGPVGEALIMTGLGIAVAIP
AVVFYNLAVRINRSIMYQANDRAHDLLAQSAELAVTQQSSINNEPAVTQAQLVKGNHTETQAPQQTEHYHKSAPSQP

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=207, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789381, Length=194, Percent_Identity=28.3505154639175, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26096; Mature: 25965

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLTRESDMDFTTYWQYSDMVTRTLFFLLLALSIISWVTGIIRVLQSRKLVTTVADDLS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QQMQEKRSDLSVADAATRRLITEQTLLKHIGRYRFASERGLPILGTTAAIAPFIGLFGTV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHH
WGIFHALRNIGMSGQAGLGQVAGPVGEALIMTGLGIAVAIPAVVFYNLAVRINRSIMYQA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEC
NDRAHDLLAQSAELAVTQQSSINNEPAVTQAQLVKGNHTETQAPQQTEHYHKSAPSQP
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
AQLTRESDMDFTTYWQYSDMVTRTLFFLLLALSIISWVTGIIRVLQSRKLVTTVADDLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QQMQEKRSDLSVADAATRRLITEQTLLKHIGRYRFASERGLPILGTTAAIAPFIGLFGTV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHH
WGIFHALRNIGMSGQAGLGQVAGPVGEALIMTGLGIAVAIPAVVFYNLAVRINRSIMYQA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEC
NDRAHDLLAQSAELAVTQQSSINNEPAVTQAQLVKGNHTETQAPQQTEHYHKSAPSQP
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]