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The map label for this gene is otsA [H]

Identifier: 93006626

GI number: 93006626

Start: 2225020

End: 2226621

Strand: Reverse

Name: otsA [H]

Synonym: Pcryo_1802

Alternate gene names: 93006626

Gene position: 2226621-2225020 (Counterclockwise)

Preceding gene: 93006627

Following gene: 93006625

Centisome position: 72.77

GC content: 39.45

Gene sequence:

>1602_bases
ATGAGCCGCTTAATCGTCTTGTCTAATCGGGTTAAAATGCCTGATAAAAATCCAATGGCAGGCGGACTGGCGATAGCACT
GCAAGACGTGTTAATGGAAAAATCAGTCATTTGGATGGGCTGGAATGGTGAAATTGTTAATAGACTTGATGAAGATTTCT
CTCATGAATTTAGTATTACCAAACAAGCTGTCTTATCAGGCATAGATATATCACAGGGCAAGACTTCTATTACCTATATG
ACCACTGCTTTTACGACTGAGCAATATCAGCAGTTTTACTGTGGGTTTGCCAATAATGTATTGTGGCCATTATTGCACGA
GCGACCTGATTTAATTCATGAAACACCAGAGGATTACGCAGGCTATCAAGAGGTAAACCGTCTTTTTGCTAAGCAATTAA
AGAAGATTATTAAGCCTGATGATGTGATTTGGGTTCATGATTATCACTTTTTAAGTGTGGCATATCATTGTAGGCAGTTG
GGTATTCACAATCGTATCGGATTTTTTTTACACATCCCATTTGTCTCATTGCCATTTTGGCAATCGCTTGATAAAAGCGA
TGAGCTCATTAGGCACCTTGCTCATTATGACGTACTTGGTACACAAACTCATCAAGGTAGAGCCAACTGCCTTGCGGTTT
GCAGATATTATTTAACAGATAAGATTTTAGAAGTTTGTTCTTTAGAGCTCTCACCAATAAATGTTTTACACGACAAACAT
GCTGCTACTCTATATAAATCATCTGATGTGCAGTTACTGCTCAATTTAGATTTAAAATCCCAGCATTCTTTAATGGTTAA
GGCTTATCCAATCGGTGTGAATGTGGAGAGAATCCAACAACAGGTCAGTCCCTTGTCTTCGCAGTGCTCAGTACAATCCG
TCAAAGCTCATCAGAGCAAAAAAGGCATAAAGTATAACGCCCAGCAGATTATTGCAGTAGATAGAATTGATTACTCAAAA
GGTTTATTAAAACGTTTTTCAGCATATCGCAATTTTTTACAGCAAAATCCGTCCTATCAGAATCAACTGAAATTATTACA
AATCGCCTGTCCTAGTCGCTTAGATGTGTCTGCTTATCAACAACTTCATCATGATGTTAAAACTGCTGTTAATGATATTA
ATCAGCAGTTTTTGCCCAGTAAGTATACAAAAGATGCTTCTACAGATAATTGGCAAGCTATCAACTATGACGAAAGTGTA
ATAAGCCACGAGACACTAATGACGATGTTTTGGCAGAGTGATATCGGCTGGGTCAATTCGCTCAAAGATGGTATGAATCT
GGTTGCCAAAGAGTATATTGCAGCGCAAAATCCTGATAATCCTGGCGTGCTATTGCTCTCACGTTACGCTGGGGCAGCGG
CGCAAATGCAAGCCGCAGTCATTATCGATCCACATCAACCAAAAAGTATGACAGACGGTTTAGGGATTGCTTTGACAATG
CCATTAGGTGAGCGGCAGTCACGCTATCAATCTCTACTGCAAGGACTGCAAAAAGATAACTTGCAAGCTTGGCAGCAGAG
TTTTTTAGATGATCTGTATGATGTTAAAAGGCGACAAACAGATATTTCGAAACCTGTCACAGTCCAAATGTCTGACTCAT
AA

Upstream 100 bases:

>100_bases
ATGTACGTAATACTCATGAGGTCACCATATTACTGAATAGCTTTTTAAGCTTTTGCCAAGAGCATTCAATGCTAGCAAAA
GAAACAGTGAGGCACGTGAT

Downstream 100 bases:

>100_bases
GAACGATTAGGAGACCCTTATGCTACCGTTAGATGCAACAAATCCTTTATTATCAGAGATTAAAGCCAGTATAGACAATA
TCATACATACTAATAATCAA

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MSRLIVLSNRVKMPDKNPMAGGLAIALQDVLMEKSVIWMGWNGEIVNRLDEDFSHEFSITKQAVLSGIDISQGKTSITYM
TTAFTTEQYQQFYCGFANNVLWPLLHERPDLIHETPEDYAGYQEVNRLFAKQLKKIIKPDDVIWVHDYHFLSVAYHCRQL
GIHNRIGFFLHIPFVSLPFWQSLDKSDELIRHLAHYDVLGTQTHQGRANCLAVCRYYLTDKILEVCSLELSPINVLHDKH
AATLYKSSDVQLLLNLDLKSQHSLMVKAYPIGVNVERIQQQVSPLSSQCSVQSVKAHQSKKGIKYNAQQIIAVDRIDYSK
GLLKRFSAYRNFLQQNPSYQNQLKLLQIACPSRLDVSAYQQLHHDVKTAVNDINQQFLPSKYTKDASTDNWQAINYDESV
ISHETLMTMFWQSDIGWVNSLKDGMNLVAKEYIAAQNPDNPGVLLLSRYAGAAAQMQAAVIIDPHQPKSMTDGLGIALTM
PLGERQSRYQSLLQGLQKDNLQAWQQSFLDDLYDVKRRQTDISKPVTVQMSDS

Sequences:

>Translated_533_residues
MSRLIVLSNRVKMPDKNPMAGGLAIALQDVLMEKSVIWMGWNGEIVNRLDEDFSHEFSITKQAVLSGIDISQGKTSITYM
TTAFTTEQYQQFYCGFANNVLWPLLHERPDLIHETPEDYAGYQEVNRLFAKQLKKIIKPDDVIWVHDYHFLSVAYHCRQL
GIHNRIGFFLHIPFVSLPFWQSLDKSDELIRHLAHYDVLGTQTHQGRANCLAVCRYYLTDKILEVCSLELSPINVLHDKH
AATLYKSSDVQLLLNLDLKSQHSLMVKAYPIGVNVERIQQQVSPLSSQCSVQSVKAHQSKKGIKYNAQQIIAVDRIDYSK
GLLKRFSAYRNFLQQNPSYQNQLKLLQIACPSRLDVSAYQQLHHDVKTAVNDINQQFLPSKYTKDASTDNWQAINYDESV
ISHETLMTMFWQSDIGWVNSLKDGMNLVAKEYIAAQNPDNPGVLLLSRYAGAAAQMQAAVIIDPHQPKSMTDGLGIALTM
PLGERQSRYQSLLQGLQKDNLQAWQQSFLDDLYDVKRRQTDISKPVTVQMSDS
>Mature_532_residues
SRLIVLSNRVKMPDKNPMAGGLAIALQDVLMEKSVIWMGWNGEIVNRLDEDFSHEFSITKQAVLSGIDISQGKTSITYMT
TAFTTEQYQQFYCGFANNVLWPLLHERPDLIHETPEDYAGYQEVNRLFAKQLKKIIKPDDVIWVHDYHFLSVAYHCRQLG
IHNRIGFFLHIPFVSLPFWQSLDKSDELIRHLAHYDVLGTQTHQGRANCLAVCRYYLTDKILEVCSLELSPINVLHDKHA
ATLYKSSDVQLLLNLDLKSQHSLMVKAYPIGVNVERIQQQVSPLSSQCSVQSVKAHQSKKGIKYNAQQIIAVDRIDYSKG
LLKRFSAYRNFLQQNPSYQNQLKLLQIACPSRLDVSAYQQLHHDVKTAVNDINQQFLPSKYTKDASTDNWQAINYDESVI
SHETLMTMFWQSDIGWVNSLKDGMNLVAKEYIAAQNPDNPGVLLLSRYAGAAAQMQAAVIIDPHQPKSMTDGLGIALTMP
LGERQSRYQSLLQGLQKDNLQAWQQSFLDDLYDVKRRQTDISKPVTVQMSDS

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=523, Percent_Identity=34.7992351816444, Blast_Score=294, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71987012, Length=461, Percent_Identity=25.3796095444685, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI115533560, Length=469, Percent_Identity=25.7995735607676, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI115533558, Length=469, Percent_Identity=25.7995735607676, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319602, Length=530, Percent_Identity=28.3018867924528, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6323537, Length=492, Percent_Identity=23.780487804878, Blast_Score=133, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6323917, Length=492, Percent_Identity=22.7642276422764, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320279, Length=453, Percent_Identity=21.8543046357616, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI19920676, Length=555, Percent_Identity=27.9279279279279, Blast_Score=212, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 60752; Mature: 60621

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIVLSNRVKMPDKNPMAGGLAIALQDVLMEKSVIWMGWNGEIVNRLDEDFSHEFSIT
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
KQAVLSGIDISQGKTSITYMTTAFTTEQYQQFYCGFANNVLWPLLHERPDLIHETPEDYA
HHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCHHHC
GYQEVNRLFAKQLKKIIKPDDVIWVHDYHFLSVAYHCRQLGIHNRIGFFLHIPFVSLPFW
CHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCHH
QSLDKSDELIRHLAHYDVLGTQTHQGRANCLAVCRYYLTDKILEVCSLELSPINVLHDKH
HHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCH
AATLYKSSDVQLLLNLDLKSQHSLMVKAYPIGVNVERIQQQVSPLSSQCSVQSVKAHQSK
HHHEEECCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHC
KGIKYNAQQIIAVDRIDYSKGLLKRFSAYRNFLQQNPSYQNQLKLLQIACPSRLDVSAYQ
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCCHHHHH
QLHHDVKTAVNDINQQFLPSKYTKDASTDNWQAINYDESVISHETLMTMFWQSDIGWVNS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHH
LKDGMNLVAKEYIAAQNPDNPGVLLLSRYAGAAAQMQAAVIIDPHQPKSMTDGLGIALTM
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHEEEEEEECCCCCCCCCCCCCEEEEC
PLGERQSRYQSLLQGLQKDNLQAWQQSFLDDLYDVKRRQTDISKPVTVQMSDS
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure 
SRLIVLSNRVKMPDKNPMAGGLAIALQDVLMEKSVIWMGWNGEIVNRLDEDFSHEFSIT
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
KQAVLSGIDISQGKTSITYMTTAFTTEQYQQFYCGFANNVLWPLLHERPDLIHETPEDYA
HHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCHHHC
GYQEVNRLFAKQLKKIIKPDDVIWVHDYHFLSVAYHCRQLGIHNRIGFFLHIPFVSLPFW
CHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCHH
QSLDKSDELIRHLAHYDVLGTQTHQGRANCLAVCRYYLTDKILEVCSLELSPINVLHDKH
HHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCH
AATLYKSSDVQLLLNLDLKSQHSLMVKAYPIGVNVERIQQQVSPLSSQCSVQSVKAHQSK
HHHEEECCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHC
KGIKYNAQQIIAVDRIDYSKGLLKRFSAYRNFLQQNPSYQNQLKLLQIACPSRLDVSAYQ
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCCHHHHH
QLHHDVKTAVNDINQQFLPSKYTKDASTDNWQAINYDESVISHETLMTMFWQSDIGWVNS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHH
LKDGMNLVAKEYIAAQNPDNPGVLLLSRYAGAAAQMQAAVIIDPHQPKSMTDGLGIALTM
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHEEEEEEECCCCCCCCCCCCCEEEEC
PLGERQSRYQSLLQGLQKDNLQAWQQSFLDDLYDVKRRQTDISKPVTVQMSDS
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA