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The map label for this gene is ampC [H]

Identifier: 93006599

GI number: 93006599

Start: 2195967

End: 2197157

Strand: Reverse

Name: ampC [H]

Synonym: Pcryo_1775

Alternate gene names: 93006599

Gene position: 2197157-2195967 (Counterclockwise)

Preceding gene: 93006600

Following gene: 93006597

Centisome position: 71.81

GC content: 40.64

Gene sequence:

>1191_bases
ATGAGAAACCCTATAATGAAACAACCCTTTCAAACCTTTTTAAATCAAGTGGGATTTACCGCTTTAGTGACAGCATCATT
ACTATCTGGAACCGTACAAGCAGCGGATAACAATGACCATCTAAAGAGCGCTGTTGATCAACAAGCCAAATTACTAATGA
ATGAGCATAATATTTCAGGAATGGCTTTTGGCGTCATCATCGATGGCAAATCACATTTTTATCATTATGGTTTGGCTGAT
AAGAAAGCCAAAATACCTGTCTCAGAAAACACTATTTTTGAGCTAGGCTCAATCAGTAAGACGTTTGCGGCTACCTTAGC
CAGTTATTCAGAATTAAATGGCACACTTACATTAGAAGATACTGCTGATAAATATATTCCCTACCTAAAAAACAGCGCCA
TTGGTAACACCAAGCTTATAAACCTAGCCACCTATTCAGCTGGTGGTCTACCGCTACAAGTCCCTGATGACGTCAAAAAC
AATAAAGAGTTGCTACGTTATTATAAATCTTGGCAGCCAGTCTTTCCTGTCAACTCAAAGCGTCTGTATTCCAACGCCAG
TATCGGTCTGTTTGGTTATATATCGGCATTGAGCATGGACACTGATTACACACAATTGATGGAAGAAAAAATACTGCCAT
CACTCAATATGCCCAATACTTTTATCAATGTGCCTAGTGACAAGATGGCAGATTATGCGTTTGGTTACAACGCTGCTGGC
GATGCTATCCGAGTCAATCCTGGCATGTTAGACGCTGAAACCTATGGCATTAAATCCACCATCACAGATATGACGCATTT
TATGGCAGCGAATATGGGTCTTGTGCCGCTAGATAAAAATATTCAGCAAGCGTTAGACAATAATAGAAAGGGTTACTATC
AGGCGAGCACTTTTACCCAAGGGTTAGGATGGGAGATGTACCCTTATCCTACTCAGCTAGATACCTTGCTTGAAGGCAAC
TCGATGGACGTGGTACTAAAGCCTCAAGCCATCAAAACAGACAATCATCCAACGGCTGTTTTAAATAACGTCTGGGTAAA
TAAGACAGGTGCTACTAATGGGTTTGGTGGCTATATCGCTTATATTCCTGCCGAAAAATCAGGCATTGTCATTCTGGCAA
ATAAAAACTATCCAAATGCAGATAGGGTCAAAGCAGCGTATACGATTTTAGAGAGTGCGATAACTCATTGA

Upstream 100 bases:

>100_bases
GAGATTCAGCATTCTGAGATAATGCAAAACGGCATACCCGAACTGAAAGCAAAGCGCTATTTGCATGCTCACTAAATTAT
CAGTACATCTATCAGAATAA

Downstream 100 bases:

>100_bases
TTGAGCATGAGTCACAAAGCAACCTTATAAAAATGGCCTTTCACTAATAACCCAGCTAGATGCTGGGTTATTATGTTCAA
CTTTTAAGAGCAGCCTTCCA

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRNPIMKQPFQTFLNQVGFTALVTASLLSGTVQAADNNDHLKSAVDQQAKLLMNEHNISGMAFGVIIDGKSHFYHYGLAD
KKAKIPVSENTIFELGSISKTFAATLASYSELNGTLTLEDTADKYIPYLKNSAIGNTKLINLATYSAGGLPLQVPDDVKN
NKELLRYYKSWQPVFPVNSKRLYSNASIGLFGYISALSMDTDYTQLMEEKILPSLNMPNTFINVPSDKMADYAFGYNAAG
DAIRVNPGMLDAETYGIKSTITDMTHFMAANMGLVPLDKNIQQALDNNRKGYYQASTFTQGLGWEMYPYPTQLDTLLEGN
SMDVVLKPQAIKTDNHPTAVLNNVWVNKTGATNGFGGYIAYIPAEKSGIVILANKNYPNADRVKAAYTILESAITH

Sequences:

>Translated_396_residues
MRNPIMKQPFQTFLNQVGFTALVTASLLSGTVQAADNNDHLKSAVDQQAKLLMNEHNISGMAFGVIIDGKSHFYHYGLAD
KKAKIPVSENTIFELGSISKTFAATLASYSELNGTLTLEDTADKYIPYLKNSAIGNTKLINLATYSAGGLPLQVPDDVKN
NKELLRYYKSWQPVFPVNSKRLYSNASIGLFGYISALSMDTDYTQLMEEKILPSLNMPNTFINVPSDKMADYAFGYNAAG
DAIRVNPGMLDAETYGIKSTITDMTHFMAANMGLVPLDKNIQQALDNNRKGYYQASTFTQGLGWEMYPYPTQLDTLLEGN
SMDVVLKPQAIKTDNHPTAVLNNVWVNKTGATNGFGGYIAYIPAEKSGIVILANKNYPNADRVKAAYTILESAITH
>Mature_396_residues
MRNPIMKQPFQTFLNQVGFTALVTASLLSGTVQAADNNDHLKSAVDQQAKLLMNEHNISGMAFGVIIDGKSHFYHYGLAD
KKAKIPVSENTIFELGSISKTFAATLASYSELNGTLTLEDTADKYIPYLKNSAIGNTKLINLATYSAGGLPLQVPDDVKN
NKELLRYYKSWQPVFPVNSKRLYSNASIGLFGYISALSMDTDYTQLMEEKILPSLNMPNTFINVPSDKMADYAFGYNAAG
DAIRVNPGMLDAETYGIKSTITDMTHFMAANMGLVPLDKNIQQALDNNRKGYYQASTFTQGLGWEMYPYPTQLDTLLEGN
SMDVVLKPQAIKTDNHPTAVLNNVWVNKTGATNGFGGYIAYIPAEKSGIVILANKNYPNADRVKAAYTILESAITH

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=377, Percent_Identity=41.1140583554377, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 43499; Mature: 43499

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNPIMKQPFQTFLNQVGFTALVTASLLSGTVQAADNNDHLKSAVDQQAKLLMNEHNISG
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHCCCCCE
MAFGVIIDGKSHFYHYGLADKKAKIPVSENTIFELGSISKTFAATLASYSELNGTLTLED
EEEEEEECCCCCEEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEEEEC
TADKYIPYLKNSAIGNTKLINLATYSAGGLPLQVPDDVKNNKELLRYYKSWQPVFPVNSK
CCHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCCC
RLYSNASIGLFGYISALSMDTDYTQLMEEKILPSLNMPNTFINVPSDKMADYAFGYNAAG
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHCCCCCCC
DAIRVNPGMLDAETYGIKSTITDMTHFMAANMGLVPLDKNIQQALDNNRKGYYQASTFTQ
CEEEECCCEECCHHCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCEEEECCCCC
GLGWEMYPYPTQLDTLLEGNSMDVVLKPQAIKTDNHPTAVLNNVWVNKTGATNGFGGYIA
CCCCCCCCCCCHHHHHHCCCCEEEEECCCEECCCCCCCEEEECEEEECCCCCCCCCCEEE
YIPAEKSGIVILANKNYPNADRVKAAYTILESAITH
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNPIMKQPFQTFLNQVGFTALVTASLLSGTVQAADNNDHLKSAVDQQAKLLMNEHNISG
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHCCCCCE
MAFGVIIDGKSHFYHYGLADKKAKIPVSENTIFELGSISKTFAATLASYSELNGTLTLED
EEEEEEECCCCCEEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEEEEC
TADKYIPYLKNSAIGNTKLINLATYSAGGLPLQVPDDVKNNKELLRYYKSWQPVFPVNSK
CCHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCCC
RLYSNASIGLFGYISALSMDTDYTQLMEEKILPSLNMPNTFINVPSDKMADYAFGYNAAG
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHCCCCCCC
DAIRVNPGMLDAETYGIKSTITDMTHFMAANMGLVPLDKNIQQALDNNRKGYYQASTFTQ
CEEEECCCEECCHHCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCEEEECCCCC
GLGWEMYPYPTQLDTLLEGNSMDVVLKPQAIKTDNHPTAVLNNVWVNKTGATNGFGGYIA
CCCCCCCCCCCHHHHHHCCCCEEEEECCCEECCCCCCCEEEECEEEECCCCCCCCCCEEE
YIPAEKSGIVILANKNYPNADRVKAAYTILESAITH
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063463 [H]