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The map label for this gene is hupR1 [H]

Identifier: 93006590

GI number: 93006590

Start: 2184649

End: 2185584

Strand: Reverse

Name: hupR1 [H]

Synonym: Pcryo_1766

Alternate gene names: 93006590

Gene position: 2185584-2184649 (Counterclockwise)

Preceding gene: 93006591

Following gene: 93006588

Centisome position: 71.43

GC content: 40.17

Gene sequence:

>936_bases
ATGCAAAAACCAAAAATCGCTTTTATCGATGATGAGCCACGCATTTTACGCAGTTTAAAAATGCATTTTCGCCAGTCACA
TGATGTATTTATCACTACTGATGCTAGCGAATTGATGAAGTATGTTAGCGAGCATGATGTACAAGTGGTCATCAGCGACC
AACGTATGCCAGATAAGCAAGGTACAGAAGTGTTGCGTGATATCAAAGCGGCCTCACCAAATACACTACGTATTTTGCTG
ACCGGTTATGCTGATTTGAATGCAGTGATTGACTCTGTGAATGAGGGCGAAATTTATCGTTATATCACAAAGCCATGGCA
AAATGATGAGCTTAAACAAATCGTCAATAAAGCCACAGAAATTGCTCAGCAAACGCAAGAAATCACCCAAAACACTATGC
AAGGTAATGACACTCAAAAAGTTAGTGGTGGCACTGGTAGCAATCGTAATATATTGGTATTAGATGACGACGAGAGCGTC
TATCAGCAAATAAAAAGTCATGTTAAGAGCGCTTATACCGTGAGTTGGGCCAGTAACCTTGAACAGGCAGCAAGGTTATT
ACAAAAAAAACGCTTTGGCGTCACTATTACGGATTCGACACTCAATAAAGAAAATATTACCCCCATTGTTTATGCTTTAA
AGAATATTCAGCCAGATTTGATGGTTCTTATGTTGACTGAATTCAAAGATGCCCATATGGTCATTGATTTAATTAATAAA
GGTCAAGTATATCGCTGTCTACCACGGCCGACCAACTTCTCTATCATGAGTATCAGTCTGGATCGCGCTTTTGATCATCA
TGAAAGATTGCTAGAACAGCCGATACTGGCGGCTCGCCATCATGTCGAGGAGGTAACAGAATCGGAGGCTTTGAATTTTT
CTGAAAGACTTAAGGGTTTCTTTGCTAAGTTCAGAGGTTGGCGCATTATTAGATAG

Upstream 100 bases:

>100_bases
TATTAGGTTGCCGATACAGTCTAGCGCTCATGAACCTAAACCTTCACAAGCTTTATTTGAAAGTTGAGAGACTTCCCATC
ACTTATTTAAAGAGAGCGTC

Downstream 100 bases:

>100_bases
AATATAGCCTCAGATATAATCAATAATGGCACTCCTAGCTTCAGCGAATGTCTGACTGGTGTGATATGCCATCTGTAGCG
CCTTAGCGGTCAGCATACTG

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQKPKIAFIDDEPRILRSLKMHFRQSHDVFITTDASELMKYVSEHDVQVVISDQRMPDKQGTEVLRDIKAASPNTLRILL
TGYADLNAVIDSVNEGEIYRYITKPWQNDELKQIVNKATEIAQQTQEITQNTMQGNDTQKVSGGTGSNRNILVLDDDESV
YQQIKSHVKSAYTVSWASNLEQAARLLQKKRFGVTITDSTLNKENITPIVYALKNIQPDLMVLMLTEFKDAHMVIDLINK
GQVYRCLPRPTNFSIMSISLDRAFDHHERLLEQPILAARHHVEEVTESEALNFSERLKGFFAKFRGWRIIR

Sequences:

>Translated_311_residues
MQKPKIAFIDDEPRILRSLKMHFRQSHDVFITTDASELMKYVSEHDVQVVISDQRMPDKQGTEVLRDIKAASPNTLRILL
TGYADLNAVIDSVNEGEIYRYITKPWQNDELKQIVNKATEIAQQTQEITQNTMQGNDTQKVSGGTGSNRNILVLDDDESV
YQQIKSHVKSAYTVSWASNLEQAARLLQKKRFGVTITDSTLNKENITPIVYALKNIQPDLMVLMLTEFKDAHMVIDLINK
GQVYRCLPRPTNFSIMSISLDRAFDHHERLLEQPILAARHHVEEVTESEALNFSERLKGFFAKFRGWRIIR
>Mature_311_residues
MQKPKIAFIDDEPRILRSLKMHFRQSHDVFITTDASELMKYVSEHDVQVVISDQRMPDKQGTEVLRDIKAASPNTLRILL
TGYADLNAVIDSVNEGEIYRYITKPWQNDELKQIVNKATEIAQQTQEITQNTMQGNDTQKVSGGTGSNRNILVLDDDESV
YQQIKSHVKSAYTVSWASNLEQAARLLQKKRFGVTITDSTLNKENITPIVYALKNIQPDLMVLMLTEFKDAHMVIDLINK
GQVYRCLPRPTNFSIMSISLDRAFDHHERLLEQPILAARHHVEEVTESEALNFSERLKGFFAKFRGWRIIR

Specific function: Probable member of the two-component regulatory system involved in the regulation of the [NiFe] hydrogenase activity. HupR1 is probably phosphorylated by the sensory component and then acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 35730; Mature: 35730

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKPKIAFIDDEPRILRSLKMHFRQSHDVFITTDASELMKYVSEHDVQVVISDQRMPDKQ
CCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCEEEEEECCCCCCHH
GTEVLRDIKAASPNTLRILLTGYADLNAVIDSVNEGEIYRYITKPWQNDELKQIVNKATE
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHH
IAQQTQEITQNTMQGNDTQKVSGGTGSNRNILVLDDDESVYQQIKSHVKSAYTVSWASNL
HHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHEEHHHHHHH
EQAARLLQKKRFGVTITDSTLNKENITPIVYALKNIQPDLMVLMLTEFKDAHMVIDLINK
HHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHCCCHHHEEHHHHHCCCHHHHEEECCC
GQVYRCLPRPTNFSIMSISLDRAFDHHERLLEQPILAARHHVEEVTESEALNFSERLKGF
CCEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
FAKFRGWRIIR
HHHHCCCEECC
>Mature Secondary Structure
MQKPKIAFIDDEPRILRSLKMHFRQSHDVFITTDASELMKYVSEHDVQVVISDQRMPDKQ
CCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCEEEEEECCCCCCHH
GTEVLRDIKAASPNTLRILLTGYADLNAVIDSVNEGEIYRYITKPWQNDELKQIVNKATE
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHH
IAQQTQEITQNTMQGNDTQKVSGGTGSNRNILVLDDDESVYQQIKSHVKSAYTVSWASNL
HHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHEEHHHHHHH
EQAARLLQKKRFGVTITDSTLNKENITPIVYALKNIQPDLMVLMLTEFKDAHMVIDLINK
HHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHCCCHHHEEHHHHHCCCHHHHEEECCC
GQVYRCLPRPTNFSIMSISLDRAFDHHERLLEQPILAARHHVEEVTESEALNFSERLKGF
CCEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
FAKFRGWRIIR
HHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1885559; 8497190; 2007559 [H]