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The map label for this gene is mutT [C]

Identifier: 93006510

GI number: 93006510

Start: 2076136

End: 2077218

Strand: Reverse

Name: mutT [C]

Synonym: Pcryo_1686

Alternate gene names: 93006510

Gene position: 2077218-2076136 (Counterclockwise)

Preceding gene: 93006512

Following gene: 93006509

Centisome position: 67.89

GC content: 42.57

Gene sequence:

>1083_bases
ATGACAGTCAAACAAAGTAACTCTCTAACAAACACTTCAATAACGACAGTCAATGTAGCGGTTGCCGTTATTCATTATCA
AAATCAGTATCTACTAGGATTTAGAGCGGCTTCTCAGCACCAAGGCAACCGTTATGAGTTTGTAGGCGGAAAGATAGACG
CTCATGAAACAGCAAAACAAGGGCTGATACGAGAAGTTGCTGAAGAGACAGGTATCAATATTGCTAATAATACGGCAGTT
AAACTCGGTCGATTGCATCATGATTATGGTGATAAGCAGGTCTGCTTACAAGTTTACCGTATTGAAGTGACTGCACAACA
ATATGCGCAATATAAAAACCTAAGCTATGGTCTAGAAGGTCAAAAGCTAACATGGGTAGAGGAGGCAGAGCTGCTGGCAG
GGCATTATGATTTACCCGCTGCTAATAAGACAATCCTTGCGTGGTTACAGTTGCCTATGCAGATCACAGTTACTTATCCA
TTATCGCATTTTGATGCTGCCTCTAATCCTATAGCAGCATGGTTACAGTATCATCATGAGCATATAACGGCTGGTGCTTG
GGTTTATATGCGGACAAAAGCAGCAGGGACAGAAAACAGTATCAAGCAGCTATTACAACTACGTACTGATATTCAAGCGA
TTACTCCTGACCACTTAGATATGGACAAAGCAGACAATGTAGAAGCAAATAATCAAATAATAGCAAGTCATTTAACACAG
ACACAGCTTATGCAATGGTCAAGCGGAGTAGCTAAGGAGCCCATGTCGTACTCTGCCTTGTCTACAAGCTTGCCATTAAT
CGTTAGTTGCCATGATGTAGATAGTATTAATGCTGCCAATCAACTGGCGTCTATTCGATTACAGCAGCAGTTGCCACCCG
TTATCGGTATTTTCTTGGCACCTGTTGAGTGTACCCAAACCCATCCTGATACACCGGCATTAGGATGGGAGGCGTGGTCA
AATTTAGCAAATTTAGCGGATATGCCAGTTATCGGCTTAGGTGGACTATCGCCTATGATGTATAAACAAGCCGTGCTACA
TGGAGGCGTTGCTGTTGCTGGAATTCGCCAGTTTTTAAAATAG

Upstream 100 bases:

>100_bases
ATTTATAAAATAAATAACAGCGATTATGTAAACTTATCTAACCGTTTTTTTATTTAAACAATCTTAGCCATCAATCTTAG
TAGCATTAAAGGAAAATAGA

Downstream 100 bases:

>100_bases
TTTTTGGTACTATGGTTAACCGCATTTTTATAACAATTTTGGGCATTAAGCTGCCATTTGAACACCGCTAAAACCAGACT
ATGATAGGTCAAATAAAAAA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: Thiamine Monophosphate Synthase; Nucleoside Triphosphate Pyrophosphohydrolase; NUDIX Hydrolase; Mutator Protein MutT; 7 8-Dihydro-8-Oxoguanine-Triphosphatase; Mutator MutT; 78-Dihydro-8-Oxoguanine-Triphosphatase Prefers DGTP; Hydrolase NUDIX Family; MutT/NUDIX Family Protein; (Di)Nucleoside Polyphosphate Hydrolase; MutT/Nudix Family Protein; NTP Pyrophosphohydrolase Including Oxidative Damage Repair; Mutator Protein; MutT Protein; 8-Oxo-DGTPase

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTVKQSNSLTNTSITTVNVAVAVIHYQNQYLLGFRAASQHQGNRYEFVGGKIDAHETAKQGLIREVAEETGINIANNTAV
KLGRLHHDYGDKQVCLQVYRIEVTAQQYAQYKNLSYGLEGQKLTWVEEAELLAGHYDLPAANKTILAWLQLPMQITVTYP
LSHFDAASNPIAAWLQYHHEHITAGAWVYMRTKAAGTENSIKQLLQLRTDIQAITPDHLDMDKADNVEANNQIIASHLTQ
TQLMQWSSGVAKEPMSYSALSTSLPLIVSCHDVDSINAANQLASIRLQQQLPPVIGIFLAPVECTQTHPDTPALGWEAWS
NLANLADMPVIGLGGLSPMMYKQAVLHGGVAVAGIRQFLK

Sequences:

>Translated_360_residues
MTVKQSNSLTNTSITTVNVAVAVIHYQNQYLLGFRAASQHQGNRYEFVGGKIDAHETAKQGLIREVAEETGINIANNTAV
KLGRLHHDYGDKQVCLQVYRIEVTAQQYAQYKNLSYGLEGQKLTWVEEAELLAGHYDLPAANKTILAWLQLPMQITVTYP
LSHFDAASNPIAAWLQYHHEHITAGAWVYMRTKAAGTENSIKQLLQLRTDIQAITPDHLDMDKADNVEANNQIIASHLTQ
TQLMQWSSGVAKEPMSYSALSTSLPLIVSCHDVDSINAANQLASIRLQQQLPPVIGIFLAPVECTQTHPDTPALGWEAWS
NLANLADMPVIGLGGLSPMMYKQAVLHGGVAVAGIRQFLK
>Mature_359_residues
TVKQSNSLTNTSITTVNVAVAVIHYQNQYLLGFRAASQHQGNRYEFVGGKIDAHETAKQGLIREVAEETGINIANNTAVK
LGRLHHDYGDKQVCLQVYRIEVTAQQYAQYKNLSYGLEGQKLTWVEEAELLAGHYDLPAANKTILAWLQLPMQITVTYPL
SHFDAASNPIAAWLQYHHEHITAGAWVYMRTKAAGTENSIKQLLQLRTDIQAITPDHLDMDKADNVEANNQIIASHLTQT
QLMQWSSGVAKEPMSYSALSTSLPLIVSCHDVDSINAANQLASIRLQQQLPPVIGIFLAPVECTQTHPDTPALGWEAWSN
LANLADMPVIGLGGLSPMMYKQAVLHGGVAVAGIRQFLK

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786288, Length=138, Percent_Identity=29.7101449275362, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.-; 2.5.1.3

Molecular weight: Translated: 39630; Mature: 39498

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKQSNSLTNTSITTVNVAVAVIHYQNQYLLGFRAASQHQGNRYEFVGGKIDAHETAKQ
CCCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEEEECCCCCCCEEEEECCEECHHHHHHH
GLIREVAEETGINIANNTAVKLGRLHHDYGDKQVCLQVYRIEVTAQQYAQYKNLSYGLEG
HHHHHHHHHHCCEECCCCHHHHHHHHCCCCCHHHEEEHHHEEEHHHHHHHHCCCCCCCCC
QKLTWVEEAELLAGHYDLPAANKTILAWLQLPMQITVTYPLSHFDAASNPIAAWLQYHHE
CEEEEHHHHHHHHCCCCCCCCCHHEEEEEECCEEEEEEECHHHCCCCCCHHHHHHHHHHH
HITAGAWVYMRTKAAGTENSIKQLLQLRTDIQAITPDHLDMDKADNVEANNQIIASHLTQ
HHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
TQLMQWSSGVAKEPMSYSALSTSLPLIVSCHDVDSINAANQLASIRLQQQLPPVIGIFLA
HHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEHEEC
PVECTQTHPDTPALGWEAWSNLANLADMPVIGLGGLSPMMYKQAVLHGGVAVAGIRQFLK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHC
>Mature Secondary Structure 
TVKQSNSLTNTSITTVNVAVAVIHYQNQYLLGFRAASQHQGNRYEFVGGKIDAHETAKQ
CCCCCCCCCCCEEEEEEEEEEEEEECCCEEEEEEECCCCCCCEEEEECCEECHHHHHHH
GLIREVAEETGINIANNTAVKLGRLHHDYGDKQVCLQVYRIEVTAQQYAQYKNLSYGLEG
HHHHHHHHHHCCEECCCCHHHHHHHHCCCCCHHHEEEHHHEEEHHHHHHHHCCCCCCCCC
QKLTWVEEAELLAGHYDLPAANKTILAWLQLPMQITVTYPLSHFDAASNPIAAWLQYHHE
CEEEEHHHHHHHHCCCCCCCCCHHEEEEEECCEEEEEEECHHHCCCCCCHHHHHHHHHHH
HITAGAWVYMRTKAAGTENSIKQLLQLRTDIQAITPDHLDMDKADNVEANNQIIASHLTQ
HHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
TQLMQWSSGVAKEPMSYSALSTSLPLIVSCHDVDSINAANQLASIRLQQQLPPVIGIFLA
HHHHHHHCCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEHEEC
PVECTQTHPDTPALGWEAWSNLANLADMPVIGLGGLSPMMYKQAVLHGGVAVAGIRQFLK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA