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The map label for this gene is tadA [H]

Identifier: 93006499

GI number: 93006499

Start: 2061512

End: 2062105

Strand: Reverse

Name: tadA [H]

Synonym: Pcryo_1675

Alternate gene names: 93006499

Gene position: 2062105-2061512 (Counterclockwise)

Preceding gene: 93006500

Following gene: 93006498

Centisome position: 67.39

GC content: 44.11

Gene sequence:

>594_bases
ATGAAAAATTTTCTAAACGCTAATTTATTGCCTTACCAGCTAATACATAGTCCATTTACTAATGGTAATCCGCTGATAGG
TGAGCAGATTAAAACAGCTCTATTTTGGTCAGTTGAGGATATCAAGTGGATGACAGAGGCGCTAAAACTTGCCAAGCAAG
GCGCTGAGAAAGAAGAGGTGCCAGTAGGAGCTGTCTTGGTACATAACCAGCAGATTATTGGTCAGGGATTTAATGAGCCG
ATTGGACGCTGTGATGCGACGGCTCATGCTGAAATCGTAGCGTTAAGAGATGCTTGTACACGCTTAAATAATTATCGATT
GCCCCTAAAGACGACCTTATATGTGACTTTAGAACCCTGTACCATGTGCATGGGTGCGATGATTCATGCGCGCGTGGATA
GATTGGTATATGCAGCACATGAGCCGAGAGCAGGGGTGCTTGGTAGTCAAATGAACTTGGCTGAACAGCCTTTTTATAAT
CATCGTATGCAAGTCGATGCAGGCTTGTGCCGTGAGCACAGCAGCCAGATGCTCAAAGATTTTTTTCGGCAGCGTAGAAA
AGTGGCAAAAGTCAATCGCAAGATAAGCGATTAA

Upstream 100 bases:

>100_bases
TAATCGTGGTGGTTTTTTTGGTTCTAAGCCGTTTTCAAAAACCAATGATTATCTGGTGCAATATGGTCAAACGCCTATCG
ACTGGCAATTACCACAGTAA

Downstream 100 bases:

>100_bases
CAAGATATGATTCTTGCTGCTAGTGATAGGTCGCTTTGTTTGCTATAATATCGCCCTATTTACTTATTAATAGAGTGATT
TTCTTATAATGCTTTGATAA

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKNFLNANLLPYQLIHSPFTNGNPLIGEQIKTALFWSVEDIKWMTEALKLAKQGAEKEEVPVGAVLVHNQQIIGQGFNEP
IGRCDATAHAEIVALRDACTRLNNYRLPLKTTLYVTLEPCTMCMGAMIHARVDRLVYAAHEPRAGVLGSQMNLAEQPFYN
HRMQVDAGLCREHSSQMLKDFFRQRRKVAKVNRKISD

Sequences:

>Translated_197_residues
MKNFLNANLLPYQLIHSPFTNGNPLIGEQIKTALFWSVEDIKWMTEALKLAKQGAEKEEVPVGAVLVHNQQIIGQGFNEP
IGRCDATAHAEIVALRDACTRLNNYRLPLKTTLYVTLEPCTMCMGAMIHARVDRLVYAAHEPRAGVLGSQMNLAEQPFYN
HRMQVDAGLCREHSSQMLKDFFRQRRKVAKVNRKISD
>Mature_197_residues
MKNFLNANLLPYQLIHSPFTNGNPLIGEQIKTALFWSVEDIKWMTEALKLAKQGAEKEEVPVGAVLVHNQQIIGQGFNEP
IGRCDATAHAEIVALRDACTRLNNYRLPLKTTLYVTLEPCTMCMGAMIHARVDRLVYAAHEPRAGVLGSQMNLAEQPFYN
HRMQVDAGLCREHSSQMLKDFFRQRRKVAKVNRKISD

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=153, Percent_Identity=37.2549019607843, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI145693172, Length=152, Percent_Identity=51.3157894736842, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1786616, Length=157, Percent_Identity=31.2101910828025, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17541138, Length=150, Percent_Identity=38, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=109, Percent_Identity=39.4495412844037, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=30.1369863013699, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 22304; Mature: 22304

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5 ; PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFLNANLLPYQLIHSPFTNGNPLIGEQIKTALFWSVEDIKWMTEALKLAKQGAEKEEV
CCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVGAVLVHNQQIIGQGFNEPIGRCDATAHAEIVALRDACTRLNNYRLPLKTTLYVTLEPC
CEEEEEEECHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHH
TMCMGAMIHARVDRLVYAAHEPRAGVLGSQMNLAEQPFYNHRMQVDAGLCREHSSQMLKD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCEEECCHHHHHHHHHHHHHH
FFRQRRKVAKVNRKISD
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNFLNANLLPYQLIHSPFTNGNPLIGEQIKTALFWSVEDIKWMTEALKLAKQGAEKEEV
CCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVGAVLVHNQQIIGQGFNEPIGRCDATAHAEIVALRDACTRLNNYRLPLKTTLYVTLEPC
CEEEEEEECHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHH
TMCMGAMIHARVDRLVYAAHEPRAGVLGSQMNLAEQPFYNHRMQVDAGLCREHSSQMLKD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCEEECCHHHHHHHHHHHHHH
FFRQRRKVAKVNRKISD
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]