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The map label for this gene is pyrF [H]

Identifier: 93006494

GI number: 93006494

Start: 2056590

End: 2057288

Strand: Reverse

Name: pyrF [H]

Synonym: Pcryo_1670

Alternate gene names: 93006494

Gene position: 2057288-2056590 (Counterclockwise)

Preceding gene: 93006495

Following gene: 93006493

Centisome position: 67.23

GC content: 43.35

Gene sequence:

>699_bases
ATGAACAACGCAATTAATTCTCCTGTCATCGTTGCATTAGATAATATGACAAAGGATGCCTCTCTTGCATTAGCTGACCA
ATTAGATCCGGCATTATGCCGATTGAAAGTAGGTAAAGAGCTGTATACCCGCTATGGCCCTGAGATAGTCAAAGCACTGC
ATCAGCGCCAATTTGAGGTTTTTTTAGACCTTAAATTTCACGATATCCCCAATACCACTGCACAAGCAGTATTGGCTGCC
GCTGAGCTTGGTATATGGATGGTCAACGTCCATGCAAGTGCCGGTTACGATGCGATGTCATTGGCAAAACAGCGCTTGCT
AGATAATGATTTTGACACGCTATTGATAGCAGTGACTGTCTTAACATCTATGGACAATGAAGCACTCATACAAACGGGCA
TCACCGACGGCTTAGAGGCACAAGTGAGCCGCTTAGCACAATTAACCAAGCAAGCATGTCTTGATGGTGTAGTATGCTCA
GCACAAGAAGCAAAGGCATTAAAGGCATTATGTGGTCAGGACTTTAAACTGATTACGCCTGGTATCCGTCTGCTAGATGA
TAATGCTGATGATCAAAAGCGTATTTGTACGCCAAAACAGGCATTACTTGATGGCTCTGATTATTTGGTGATAGGGCGCT
CAATTACTCAAGCAGTAGATCCTGCAGCGAAATTACAGTTAATACTCCAAAGTCTCTAA

Upstream 100 bases:

>100_bases
GACCAAGCAAAAACGCGATTACTAATAATTTGTAATATGCATTTTCACTGCTGATTATAAATATAATAATTTGATAAACC
TGATATAAAGAAGCATAACA

Downstream 100 bases:

>100_bases
TTTTTCAATCAGATACTTCAGTCAAAAAGTAAAAAGACAGCCTAATCCGCTGTCTTTTTACTTTTTGTACCTAGATGAAA
AGGTGCTAAACTATTTATGT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNNAINSPVIVALDNMTKDASLALADQLDPALCRLKVGKELYTRYGPEIVKALHQRQFEVFLDLKFHDIPNTTAQAVLAA
AELGIWMVNVHASAGYDAMSLAKQRLLDNDFDTLLIAVTVLTSMDNEALIQTGITDGLEAQVSRLAQLTKQACLDGVVCS
AQEAKALKALCGQDFKLITPGIRLLDDNADDQKRICTPKQALLDGSDYLVIGRSITQAVDPAAKLQLILQSL

Sequences:

>Translated_232_residues
MNNAINSPVIVALDNMTKDASLALADQLDPALCRLKVGKELYTRYGPEIVKALHQRQFEVFLDLKFHDIPNTTAQAVLAA
AELGIWMVNVHASAGYDAMSLAKQRLLDNDFDTLLIAVTVLTSMDNEALIQTGITDGLEAQVSRLAQLTKQACLDGVVCS
AQEAKALKALCGQDFKLITPGIRLLDDNADDQKRICTPKQALLDGSDYLVIGRSITQAVDPAAKLQLILQSL
>Mature_232_residues
MNNAINSPVIVALDNMTKDASLALADQLDPALCRLKVGKELYTRYGPEIVKALHQRQFEVFLDLKFHDIPNTTAQAVLAA
AELGIWMVNVHASAGYDAMSLAKQRLLDNDFDTLLIAVTVLTSMDNEALIQTGITDGLEAQVSRLAQLTKQACLDGVVCS
AQEAKALKALCGQDFKLITPGIRLLDDNADDQKRICTPKQALLDGSDYLVIGRSITQAVDPAAKLQLILQSL

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=228, Percent_Identity=57.4561403508772, Blast_Score=246, Evalue=7e-67,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 25146; Mature: 25146

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNAINSPVIVALDNMTKDASLALADQLDPALCRLKVGKELYTRYGPEIVKALHQRQFEV
CCCCCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEE
FLDLKFHDIPNTTAQAVLAAAELGIWMVNVHASAGYDAMSLAKQRLLDNDFDTLLIAVTV
EEEEEECCCCCHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LTSMDNEALIQTGITDGLEAQVSRLAQLTKQACLDGVVCSAQEAKALKALCGQDFKLITP
HHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECC
GIRLLDDNADDQKRICTPKQALLDGSDYLVIGRSITQAVDPAAKLQLILQSL
CCEEECCCCCCHHHHCCCHHHHHCCCCEEEECCHHHHHHCHHHHHHHHHHHC
>Mature Secondary Structure
MNNAINSPVIVALDNMTKDASLALADQLDPALCRLKVGKELYTRYGPEIVKALHQRQFEV
CCCCCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEE
FLDLKFHDIPNTTAQAVLAAAELGIWMVNVHASAGYDAMSLAKQRLLDNDFDTLLIAVTV
EEEEEECCCCCHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LTSMDNEALIQTGITDGLEAQVSRLAQLTKQACLDGVVCSAQEAKALKALCGQDFKLITP
HHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECC
GIRLLDDNADDQKRICTPKQALLDGSDYLVIGRSITQAVDPAAKLQLILQSL
CCEEECCCCCCHHHHCCCHHHHHCCCCEEEECCHHHHHHCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA