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The map label for this gene is ycfH [H]

Identifier: 93006358

GI number: 93006358

Start: 1882565

End: 1883374

Strand: Reverse

Name: ycfH [H]

Synonym: Pcryo_1532

Alternate gene names: 93006358

Gene position: 1883374-1882565 (Counterclockwise)

Preceding gene: 93006359

Following gene: 93006357

Centisome position: 61.55

GC content: 43.33

Gene sequence:

>810_bases
ATGACTATAACGAGATTGTTTATGTTTACCGATAGCCACTGCCATCTTAACCGTTTAGATTTGACCAAATACGATGGTCA
ATTGTCTGGCGCAATTGCCGCGATGAAAGAAGCCAATGTCACTCGCGCGATGGCAATTATGTGTGATTTTGCTGAATATG
ATGAGATTGCCAATATCGTCAGCACCTACGGCGATGAAACGCTCAATCTTGGCATGAGCGTTGGTATTCACCCTTGTGAA
GATATCAGCGTTTTACAATCTGCAACCGTTGAACGTTTGATAGAAACGGCTAGCGCTGACCATGTGTGGGCAATAGGGGA
GACGGGACTTGATTATTACTGGTCGAAAGAAAATAAAAAAGCGCAACAAGCCAGCCTTGCCCGTCATATTCATGCCAGCC
AAAGTCTAAAAAAACCGCTTGTCATCCATATGCGTGATGCTAAAGAAGATACGATTGATATTTTAAAAGCAGAAGGTGCT
GAGCATGGCATTATTCATTGTTTCACCGAAGATTGGGAAACCGCAAAACATGCCTTAGACTTAGGGTTTTACATCTCATT
TTCAGGCATTGTCAGCTTTAAAAGCGCGCAAAATATCAAAGATGCGGCAAAAAATATGCCAAGAGACAGGATATTGATCG
AAACGGATAGCCCTTATCTAGCGCCTGTCCCCAAACGTGGTCGCCCGAATGAACCAGCTTACGTGCCTTATGTTGCCAGT
TGTATTGCAGAGATGTATGGCTGCAGTAGCGAAGAGGTCGGTACACTGACTGCAAAAAACTTTGAGAATTTACTAGCACA
GTATCATTAA

Upstream 100 bases:

>100_bases
TTGCATTAAAAGTAAGTTTGTTAAGCAGTGCTTGAAAAGTGCCCGCTTCAAAACAATAAATACGATACAAATTGAATTTT
TATCCTAATAATTTTTAAAA

Downstream 100 bases:

>100_bases
AATGGTTATGCTATGACCACTCAGTCATTTCTTGCAAGTGGCAGCTGTTTTATGCATGCCGTCTTGCAGCGTTAAATATA
AGTACATGATTATAAATGAT

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTITRLFMFTDSHCHLNRLDLTKYDGQLSGAIAAMKEANVTRAMAIMCDFAEYDEIANIVSTYGDETLNLGMSVGIHPCE
DISVLQSATVERLIETASADHVWAIGETGLDYYWSKENKKAQQASLARHIHASQSLKKPLVIHMRDAKEDTIDILKAEGA
EHGIIHCFTEDWETAKHALDLGFYISFSGIVSFKSAQNIKDAAKNMPRDRILIETDSPYLAPVPKRGRPNEPAYVPYVAS
CIAEMYGCSSEEVGTLTAKNFENLLAQYH

Sequences:

>Translated_269_residues
MTITRLFMFTDSHCHLNRLDLTKYDGQLSGAIAAMKEANVTRAMAIMCDFAEYDEIANIVSTYGDETLNLGMSVGIHPCE
DISVLQSATVERLIETASADHVWAIGETGLDYYWSKENKKAQQASLARHIHASQSLKKPLVIHMRDAKEDTIDILKAEGA
EHGIIHCFTEDWETAKHALDLGFYISFSGIVSFKSAQNIKDAAKNMPRDRILIETDSPYLAPVPKRGRPNEPAYVPYVAS
CIAEMYGCSSEEVGTLTAKNFENLLAQYH
>Mature_268_residues
TITRLFMFTDSHCHLNRLDLTKYDGQLSGAIAAMKEANVTRAMAIMCDFAEYDEIANIVSTYGDETLNLGMSVGIHPCED
ISVLQSATVERLIETASADHVWAIGETGLDYYWSKENKKAQQASLARHIHASQSLKKPLVIHMRDAKEDTIDILKAEGAE
HGIIHCFTEDWETAKHALDLGFYISFSGIVSFKSAQNIKDAAKNMPRDRILIETDSPYLAPVPKRGRPNEPAYVPYVASC
IAEMYGCSSEEVGTLTAKNFENLLAQYH

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=30.7984790874525, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=30.0380228136882, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI226061853, Length=269, Percent_Identity=29.7397769516729, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=28.90625, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI225903424, Length=227, Percent_Identity=29.5154185022026, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=28.1385281385281, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=42.5287356321839, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI48994985, Length=204, Percent_Identity=31.8627450980392, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=21.7054263565891, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559024, Length=265, Percent_Identity=27.5471698113208, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=292, Percent_Identity=29.7945205479452, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=178, Percent_Identity=30.8988764044944, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=24.7148288973384, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648690, Length=267, Percent_Identity=29.5880149812734, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330018, Length=166, Percent_Identity=33.1325301204819, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586117, Length=166, Percent_Identity=33.1325301204819, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29938; Mature: 29807

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITRLFMFTDSHCHLNRLDLTKYDGQLSGAIAAMKEANVTRAMAIMCDFAEYDEIANIV
CCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
STYGDETLNLGMSVGIHPCEDISVLQSATVERLIETASADHVWAIGETGLDYYWSKENKK
HHCCCHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCH
AQQASLARHIHASQSLKKPLVIHMRDAKEDTIDILKAEGAEHGIIHCFTEDWETAKHALD
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
LGFYISFSGIVSFKSAQNIKDAAKNMPRDRILIETDSPYLAPVPKRGRPNEPAYVPYVAS
HHEEEEEEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
CIAEMYGCSSEEVGTLTAKNFENLLAQYH
HHHHHHCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TITRLFMFTDSHCHLNRLDLTKYDGQLSGAIAAMKEANVTRAMAIMCDFAEYDEIANIV
CEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
STYGDETLNLGMSVGIHPCEDISVLQSATVERLIETASADHVWAIGETGLDYYWSKENKK
HHCCCHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCH
AQQASLARHIHASQSLKKPLVIHMRDAKEDTIDILKAEGAEHGIIHCFTEDWETAKHALD
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
LGFYISFSGIVSFKSAQNIKDAAKNMPRDRILIETDSPYLAPVPKRGRPNEPAYVPYVAS
HHEEEEEEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
CIAEMYGCSSEEVGTLTAKNFENLLAQYH
HHHHHHCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]