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The map label for this gene is kdgR [H]

Identifier: 93006338

GI number: 93006338

Start: 1859075

End: 1859833

Strand: Direct

Name: kdgR [H]

Synonym: Pcryo_1512

Alternate gene names: 93006338

Gene position: 1859075-1859833 (Clockwise)

Preceding gene: 93006336

Following gene: 93006347

Centisome position: 60.76

GC content: 44.01

Gene sequence:

>759_bases
ATGCCTAAAGTATCATCGATTACCCGTGTGCTAGAGATTATTGAGGCGGTATCTTATGCCTCAAAGCCGATTTCGCCACT
AGAGCTATCGCAGGAGCTTGATATTCCGAAGCCAACCATTCATCGATTGATTCAAAATCTGGTTGATGAAGGATTTGTGA
CAATTGATATTGGCGGCGGTATTATACCGGGTAAACGCGTACGCAATTTGGGTGTTGAGCTTTGGCAGCAGCGACTGTTC
TTTAATGAACGTCAAATGATTTTGCAAAAACTGGTCGATGAGCTAAAAGAAACCTGCGGTATCGGTGTTCCTTATCACAT
GAATATGATCTATACCAACCGCGCACAAACGACCTTGCCGATACAGATTTATTTACCAGTGGGCGCAAAGTCGCCAATGT
GGTGTACAGCGACTGGGAAGCTGTATTTAAGTCAGTTGCCGAGTGCAAGCCGCGAAAAAATACTACAAAATTTGTCACTA
GATAAGTTCACTAAAAATACCATCACTGATATCGAAAAATTAAACGCTGAGCTTGATCGTATCGCTGAAACAGGCATAGG
TATCGATAACGAAGAGTTTATCTCTGAGATGGTGGCAATCGCCGTACCGATAAGGGATAGGAAATCACGCTACCTTGCTT
CGTTATATCTGCATGCACCGACCATACGGGTGTCCTTAGATGACCTCTTAACCTATGTGCCACGACTACAAAAAGCGGCG
CAAGATATTCAGTCTCTGGTCTACGAGCTGCCAAGTTAA

Upstream 100 bases:

>100_bases
GCCTTATCGCCTTGACTGTTCTGCTCTATTTTTAGAGGCGATTATATCCGTTATAATATAGCTACTTGCTTTGTTTTTTT
ATTATTACTGAGTCATTTAT

Downstream 100 bases:

>100_bases
ATGCCTTGATATAAACTAGAAATAAGTCAAAAAAAGGTCTGCACTATTACTATAATGCCGACCTTTTTTATTTGTGTGCT
TAATAATTTAAGACAATACA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MPKVSSITRVLEIIEAVSYASKPISPLELSQELDIPKPTIHRLIQNLVDEGFVTIDIGGGIIPGKRVRNLGVELWQQRLF
FNERQMILQKLVDELKETCGIGVPYHMNMIYTNRAQTTLPIQIYLPVGAKSPMWCTATGKLYLSQLPSASREKILQNLSL
DKFTKNTITDIEKLNAELDRIAETGIGIDNEEFISEMVAIAVPIRDRKSRYLASLYLHAPTIRVSLDDLLTYVPRLQKAA
QDIQSLVYELPS

Sequences:

>Translated_252_residues
MPKVSSITRVLEIIEAVSYASKPISPLELSQELDIPKPTIHRLIQNLVDEGFVTIDIGGGIIPGKRVRNLGVELWQQRLF
FNERQMILQKLVDELKETCGIGVPYHMNMIYTNRAQTTLPIQIYLPVGAKSPMWCTATGKLYLSQLPSASREKILQNLSL
DKFTKNTITDIEKLNAELDRIAETGIGIDNEEFISEMVAIAVPIRDRKSRYLASLYLHAPTIRVSLDDLLTYVPRLQKAA
QDIQSLVYELPS
>Mature_251_residues
PKVSSITRVLEIIEAVSYASKPISPLELSQELDIPKPTIHRLIQNLVDEGFVTIDIGGGIIPGKRVRNLGVELWQQRLFF
NERQMILQKLVDELKETCGIGVPYHMNMIYTNRAQTTLPIQIYLPVGAKSPMWCTATGKLYLSQLPSASREKILQNLSLD
KFTKNTITDIEKLNAELDRIAETGIGIDNEEFISEMVAIAVPIRDRKSRYLASLYLHAPTIRVSLDDLLTYVPRLQKAAQ
DIQSLVYELPS

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=243, Percent_Identity=28.8065843621399, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082359, Length=250, Percent_Identity=26.4, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=25.5060728744939, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790752, Length=242, Percent_Identity=23.9669421487603, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786715, Length=242, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788581, Length=213, Percent_Identity=23.0046948356808, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28434; Mature: 28302

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVSSITRVLEIIEAVSYASKPISPLELSQELDIPKPTIHRLIQNLVDEGFVTIDIGGG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCC
IIPGKRVRNLGVELWQQRLFFNERQMILQKLVDELKETCGIGVPYHMNMIYTNRAQTTLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEE
IQIYLPVGAKSPMWCTATGKLYLSQLPSASREKILQNLSLDKFTKNTITDIEKLNAELDR
EEEEEECCCCCCEEEEECCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IAETGIGIDNEEFISEMVAIAVPIRDRKSRYLASLYLHAPTIRVSLDDLLTYVPRLQKAA
HHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
QDIQSLVYELPS
HHHHHHHHHCCC
>Mature Secondary Structure 
PKVSSITRVLEIIEAVSYASKPISPLELSQELDIPKPTIHRLIQNLVDEGFVTIDIGGG
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCC
IIPGKRVRNLGVELWQQRLFFNERQMILQKLVDELKETCGIGVPYHMNMIYTNRAQTTLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEE
IQIYLPVGAKSPMWCTATGKLYLSQLPSASREKILQNLSLDKFTKNTITDIEKLNAELDR
EEEEEECCCCCCEEEEECCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IAETGIGIDNEEFISEMVAIAVPIRDRKSRYLASLYLHAPTIRVSLDDLLTYVPRLQKAA
HHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
QDIQSLVYELPS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]