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The map label for this gene is mrdB [H]

Identifier: 93006311

GI number: 93006311

Start: 1827435

End: 1828577

Strand: Direct

Name: mrdB [H]

Synonym: Pcryo_1485

Alternate gene names: 93006311

Gene position: 1827435-1828577 (Clockwise)

Preceding gene: 93006309

Following gene: 93006312

Centisome position: 59.72

GC content: 45.14

Gene sequence:

>1143_bases
ATGTCTTCTAACCCGCAATATCGTTTTTCCCGACAGAGCCACCATTTCGGTCAAGGTCAGACACCGACCTTTTGGCAACG
TAGTCATATTGACCCTTGGTTGACCCTTTTATTATTGACCGTTTGTTGTATTGGGCTAACGATTTTATATAGTGCAGCCG
CTCAAGATACGAGTATGGTGCTACGACAAATGGTCAGCTATGGTGTCGCTTTTACCGTTATGTTTATCATGGCGCAGATA
CCACCGAGCCTTTATCGTACTTTTACGCCCATCTTTTATGTATTAGGTCTGATACTATTGGTGTTGGTTGATATTATCGG
TGAAGTACGTATGGGGGCGCAGCGCTGGATTAATCTACCAGGATTTGGTAGTGTGCAGCCCTCAGAGTTTATGAAGCTTG
GCATGCCTATGATGTGTGCGTGGTTTTTGTCTAAGCGTGATCTGCCCCCTTCACTACCCAGTATCGGCATTACCTTGGCG
TTAATTGTGGTGCCAGTCTTATTAATCGCTAAAGAGCCAGATCTTGGCACTTCATTATTAGTCGCTGCTAGCGGTATCTT
TGTGCTGTTTTTGGCAGGGCTATCGTGGCAACTGATAGCTGGTGCGGTTGCTTTGTCGATCCCGCTTGTTGCCTTTGCTT
GGAATTTTTTGTTACACGACTATCAGCGTACCCGTGTACTCACACTATTCAATCCTGAGGCAGATGTGCAAGGTGCTGGC
TGGAATATCATTCAGTCCAAAACTGCTATCGGCTCCGGCGGTCTAACGGGTAAAGGCTATTTAGAGGGTACGCAGTCGCA
TTTGCATTTCTTACCAGAAGGTCATACCGACTTTATTATCGCGGCTTTCTCTGAAGAGTTTGGCTTGCTTGGCGTCATAC
TATTGATGTTTATTTATGCATGCTTATTGACCCGCGCCTTATATATCGCCTTTTCTCATCCTGATACTTATAGCCGACTA
TTAGCAGGCGCGATTGCGATGTCATTTTTTGTGTATGTCTTTGTCAATGTTGGTATGGTCGGCGGTATTTTACCTGTCGT
TGGCGTACCTCTGCCTTTTATCAGTTATGGTGGTACTGCCATTGTTACTTTAATGGCAGGTTTTGGTTTACTGATGTCCA
TTCATACGCACAAGTCAGACTAA

Upstream 100 bases:

>100_bases
TATCATCTAATCGGTTAAATGCCCTATAATTATCGATTTTCTTAAGTCTTCTGCTAAATATAGCCCTTCTTCCACGCCAA
CTGCCAGTCACACTTTGCCT

Downstream 100 bases:

>100_bases
GTATCTCTGTTTTTATATCTAAAGAGACAATATTTTAATAATACGGTCTCTTTTTTTATACCCCCTATAAGCTATATCAA
GGTGCAATGGATTTTTCAGA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSSNPQYRFSRQSHHFGQGQTPTFWQRSHIDPWLTLLLLTVCCIGLTILYSAAAQDTSMVLRQMVSYGVAFTVMFIMAQI
PPSLYRTFTPIFYVLGLILLVLVDIIGEVRMGAQRWINLPGFGSVQPSEFMKLGMPMMCAWFLSKRDLPPSLPSIGITLA
LIVVPVLLIAKEPDLGTSLLVAASGIFVLFLAGLSWQLIAGAVALSIPLVAFAWNFLLHDYQRTRVLTLFNPEADVQGAG
WNIIQSKTAIGSGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVILLMFIYACLLTRALYIAFSHPDTYSRL
LAGAIAMSFFVYVFVNVGMVGGILPVVGVPLPFISYGGTAIVTLMAGFGLLMSIHTHKSD

Sequences:

>Translated_380_residues
MSSNPQYRFSRQSHHFGQGQTPTFWQRSHIDPWLTLLLLTVCCIGLTILYSAAAQDTSMVLRQMVSYGVAFTVMFIMAQI
PPSLYRTFTPIFYVLGLILLVLVDIIGEVRMGAQRWINLPGFGSVQPSEFMKLGMPMMCAWFLSKRDLPPSLPSIGITLA
LIVVPVLLIAKEPDLGTSLLVAASGIFVLFLAGLSWQLIAGAVALSIPLVAFAWNFLLHDYQRTRVLTLFNPEADVQGAG
WNIIQSKTAIGSGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVILLMFIYACLLTRALYIAFSHPDTYSRL
LAGAIAMSFFVYVFVNVGMVGGILPVVGVPLPFISYGGTAIVTLMAGFGLLMSIHTHKSD
>Mature_379_residues
SSNPQYRFSRQSHHFGQGQTPTFWQRSHIDPWLTLLLLTVCCIGLTILYSAAAQDTSMVLRQMVSYGVAFTVMFIMAQIP
PSLYRTFTPIFYVLGLILLVLVDIIGEVRMGAQRWINLPGFGSVQPSEFMKLGMPMMCAWFLSKRDLPPSLPSIGITLAL
IVVPVLLIAKEPDLGTSLLVAASGIFVLFLAGLSWQLIAGAVALSIPLVAFAWNFLLHDYQRTRVLTLFNPEADVQGAGW
NIIQSKTAIGSGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVILLMFIYACLLTRALYIAFSHPDTYSRLL
AGAIAMSFFVYVFVNVGMVGGILPVVGVPLPFISYGGTAIVTLMAGFGLLMSIHTHKSD

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=360, Percent_Identity=52.2222222222222, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1786277, Length=313, Percent_Identity=32.9073482428115, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41504; Mature: 41373

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNPQYRFSRQSHHFGQGQTPTFWQRSHIDPWLTLLLLTVCCIGLTILYSAAAQDTSMV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LRQMVSYGVAFTVMFIMAQIPPSLYRTFTPIFYVLGLILLVLVDIIGEVRMGAQRWINLP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFGSVQPSEFMKLGMPMMCAWFLSKRDLPPSLPSIGITLALIVVPVLLIAKEPDLGTSLL
CCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
VAASGIFVLFLAGLSWQLIAGAVALSIPLVAFAWNFLLHDYQRTRVLTLFNPEADVQGAG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCC
WNIIQSKTAIGSGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVILLMFIYA
CHHHHCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEECHHCCCHHHHHHHHHHHH
CLLTRALYIAFSHPDTYSRLLAGAIAMSFFVYVFVNVGMVGGILPVVGVPLPFISYGGTA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHH
IVTLMAGFGLLMSIHTHKSD
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSNPQYRFSRQSHHFGQGQTPTFWQRSHIDPWLTLLLLTVCCIGLTILYSAAAQDTSMV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LRQMVSYGVAFTVMFIMAQIPPSLYRTFTPIFYVLGLILLVLVDIIGEVRMGAQRWINLP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFGSVQPSEFMKLGMPMMCAWFLSKRDLPPSLPSIGITLALIVVPVLLIAKEPDLGTSLL
CCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
VAASGIFVLFLAGLSWQLIAGAVALSIPLVAFAWNFLLHDYQRTRVLTLFNPEADVQGAG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCC
WNIIQSKTAIGSGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVILLMFIYA
CHHHHCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEECHHCCCHHHHHHHHHHHH
CLLTRALYIAFSHPDTYSRLLAGAIAMSFFVYVFVNVGMVGGILPVVGVPLPFISYGGTA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHH
IVTLMAGFGLLMSIHTHKSD
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]