Click here to switch to the map view.

The map label for this gene is fabI [H]

Identifier: 93006250

GI number: 93006250

Start: 1749827

End: 1750633

Strand: Reverse

Name: fabI [H]

Synonym: Pcryo_1424

Alternate gene names: 93006250

Gene position: 1750633-1749827 (Counterclockwise)

Preceding gene: 93006252

Following gene: 93006249

Centisome position: 57.21

GC content: 47.83

Gene sequence:

>807_bases
ATGCTATTACAAGGACAGCGTTTTGTCGTTACAGGCATCGCTAGCAAACTATCTATCGCTTGGGCAATCGCTGAAGCACT
ACATCGTGAAGGCGCGTCGTTAATTTTGACTTATCCTAATGATAAAATCAAAAAACGGGTAGATATGGCGGCTGAAGCAT
TTGAGGCGGACTTGGTCCTTGAGTGTGACGTGGCATCAGATGCGTCTATTGCGGCTTGTTTTGAGCAAGTCACTGCCCAT
TGGGGCGATGGCATCAATGGCGTAGTACATGCGATTGGCTTTGCACCGATGGATCAGCTTGATGGTGATTTTGTCAATGC
GACAACCCGTGAAGGCAGTCATATCGCCCATGATATCTCAAGCTATAGCTTTGTGGCATTGGCAAAAGCATCGCGTGAGC
TACTTGCTATGCGCCACGGCTCAATGTTGACGTTGACTTATGAAGGCAGTATTTCAGTATTGCCAAACTACAACGTCATG
GGTATGGCAAAGGCGAGTCTTGAAGCCAGTGTTCGCTACCTTGCAACTTCTATGGGCGGTGAGGGTATTCGCGTCAACGC
GATCTCGGCAGGTCCTATTCGTACGCTTGCCGCCAGTGGCATCAAGTCATTCCGTAAAATGCTCGATATCAGTGAAAAGA
TTGCACCTCTACAGCGTAATATTACTCAAGCTGAAGTCGGTAATGCCGCGCTATTTTTATTGTCGCCTTGGGCATCTGGT
ATCACTGGCGAGATTATGTTTGTTGATGCCGGTTTCAATACGGTTGCGATCAGCGAGCAGCTAATGATGCTTGATGAGCC
GAAATAG

Upstream 100 bases:

>100_bases
AACTCATCTTTCAATTGGTACTTCCACTCGCTATTTGTTAGCCAACTATTAAAAATAATCGATCATTTAAATGACCTAAA
TTGACTTAAAAGGAAATATT

Downstream 100 bases:

>100_bases
TTAAAAGGCAATCCTCAACGATATATAATGAGAAGTAAGGAAGGCAGCCAATCGGCTGTCTTTTTTGACTATACTATGGG
TTTTTTGCTGATAAGCCATT

Product: enoyl acyl carrier protein reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLLQGQRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKIKKRVDMAAEAFEADLVLECDVASDASIAACFEQVTAH
WGDGINGVVHAIGFAPMDQLDGDFVNATTREGSHIAHDISSYSFVALAKASRELLAMRHGSMLTLTYEGSISVLPNYNVM
GMAKASLEASVRYLATSMGGEGIRVNAISAGPIRTLAASGIKSFRKMLDISEKIAPLQRNITQAEVGNAALFLLSPWASG
ITGEIMFVDAGFNTVAISEQLMMLDEPK

Sequences:

>Translated_268_residues
MLLQGQRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKIKKRVDMAAEAFEADLVLECDVASDASIAACFEQVTAH
WGDGINGVVHAIGFAPMDQLDGDFVNATTREGSHIAHDISSYSFVALAKASRELLAMRHGSMLTLTYEGSISVLPNYNVM
GMAKASLEASVRYLATSMGGEGIRVNAISAGPIRTLAASGIKSFRKMLDISEKIAPLQRNITQAEVGNAALFLLSPWASG
ITGEIMFVDAGFNTVAISEQLMMLDEPK
>Mature_268_residues
MLLQGQRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKIKKRVDMAAEAFEADLVLECDVASDASIAACFEQVTAH
WGDGINGVVHAIGFAPMDQLDGDFVNATTREGSHIAHDISSYSFVALAKASRELLAMRHGSMLTLTYEGSISVLPNYNVM
GMAKASLEASVRYLATSMGGEGIRVNAISAGPIRTLAASGIKSFRKMLDISEKIAPLQRNITQAEVGNAALFLLSPWASG
ITGEIMFVDAGFNTVAISEQLMMLDEPK

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=259, Percent_Identity=60.2316602316602, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 28639; Mature: 28639

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQGQRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKIKKRVDMAAEAFEADLVL
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCEEE
ECDVASDASIAACFEQVTAHWGDGINGVVHAIGFAPMDQLDGDFVNATTREGSHIAHDIS
EECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHCCCCEEECCCCCCCHHHHHHC
SYSFVALAKASRELLAMRHGSMLTLTYEGSISVLPNYNVMGMAKASLEASVRYLATSMGG
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCC
EGIRVNAISAGPIRTLAASGIKSFRKMLDISEKIAPLQRNITQAEVGNAALFLLSPWASG
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEEECCCCC
ITGEIMFVDAGFNTVAISEQLMMLDEPK
CCEEEEEEECCCCEEEEHHHHHCCCCCC
>Mature Secondary Structure
MLLQGQRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKIKKRVDMAAEAFEADLVL
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCEEE
ECDVASDASIAACFEQVTAHWGDGINGVVHAIGFAPMDQLDGDFVNATTREGSHIAHDIS
EECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHCCCCEEECCCCCCCHHHHHHC
SYSFVALAKASRELLAMRHGSMLTLTYEGSISVLPNYNVMGMAKASLEASVRYLATSMGG
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCC
EGIRVNAISAGPIRTLAASGIKSFRKMLDISEKIAPLQRNITQAEVGNAALFLLSPWASG
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEEECCCCC
ITGEIMFVDAGFNTVAISEQLMMLDEPK
CCEEEEEEECCCCEEEEHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10464225; 10984043 [H]