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The map label for this gene is citT [C]

Identifier: 93006247

GI number: 93006247

Start: 1747000

End: 1748424

Strand: Reverse

Name: citT [C]

Synonym: Pcryo_1421

Alternate gene names: 93006247

Gene position: 1748424-1747000 (Counterclockwise)

Preceding gene: 93006249

Following gene: 93006246

Centisome position: 57.14

GC content: 44.28

Gene sequence:

>1425_bases
ATGTCAGAGAAAAAACTAGATAGCCATCTTCCTAATGATGGCAACGAGTATTTATTTACAGATACCTTCCCAAAAGGTAC
CGGTAAAGGATTGATAGTTGTCGCTATCGCGGCGGTTATCAGTCTGTTTATCTATAACGTATTGCCGTATGATATCAGTG
CCAATAAAGGCCTCGCCATGTTGTTCTTTATCGGCGTTTTATGGTTAACTGAAGCGGTACATGTGACGATTACAGCGATA
TTGGTGGTGGTCGTAGGAGCGCTAATTGGTTTACCGGATTTCGATGCTGAAATTGGCTTACAAAGCTTTGCTAACCCAAT
TATTTATTTGTTCTTTGGTGGCTTTGCACTAGCGGCGGCATTGCATGTGCAGCAATTAGACAGGAAAATAGCGCTCAAGA
TTCTATCAATGTCAGGTGGCAATCTGAGGAATGCGGTATTCCTAATATTTGGGGTCACCGCATTTTTATCGATGTGGATA
TCAAATACGGCTACTGCAGCGATGATGTTGCCACTGGCGCTTGGTATTCTAACGCAGGTTGACCGCGAAAAAGACCGTGG
CACTTTTGTGTTCGTACTATTAGGTATTGCCTATTCTGCGAGCCTTGGTGGTTTGGGTACGATCGTTGGTTCACCACCCA
ATGCTATTGCTGCAAAAGCACTGGATATCGCGTTTGTCGATTGGATGAAGTTTGGTATTCCGATGATGTTGGTGCTGCTG
CCATTATTGCTCGGTGCGATGTATTTATTCCTCAAGCCCAATCTTAATCGTCAGGTCACGCTGAACGAAGATGATGAGGC
TATTGCATGGAATAAGCCACGTGTACTGACGATTATTGTTTTTATCGTCACAGCGCTAAGCTGGATACTCTCGAAACAAA
TTGGTGCTGCACTTAATATTGCTGATGTTGATTCTATTGTGGCACTGTTAGCAGCATCAGCGGTGGTCAGCTTAGGGTTG
GTTTCATGGAAGCAAGTTTCTGACAATACCGACTGGGGTGTGCTCATGTTGTTCGGTGGTGGTATTGCGCTATCAACAGT
GTTAAAAGTTTCAGGCGCATCGTTGGTTCTTGGTCAAGCAGTTGCTAATGGACTGTCCTCTGCACCGCTTATCGTCGTGG
TACTGGCAGTTGCGGCATTCATTATATTCTTGACAGAATTTGCTTCTAATACGGCTTCTGCCGCCTTGTTAGTCCCTGTG
TTTGCGGCTATTGCTGAGCAAATGGGTCTACCACCTGCAGTATTAGTCATGATTATTGGTATCGGTGCTTCTTGCGCATT
TATGCTACCAGTTGCCACGCCACCAAACGCTATTGTCTTTGGGACGGGTCTTATTAAGCAGACAGAGATGATACGTGTTG
GTGTCATACTGAATGTTATTTCTACCTTTATCATAGGTTTGTGGGCATATTTTTTCTTACTATAA

Upstream 100 bases:

>100_bases
ACTGTTATTAAGTACGATTATAAAGGTATGGTTAACAGCTGAAAGACGTCTTTATATTTATAATTTTTAACACCGTCTTT
GGGTACAATAAGGACATTAT

Downstream 100 bases:

>100_bases
TCTATGAGTGAAAACAGTTATAACCGAACAAACCCAATGTTTAAGTGATTCTTAAACATTGGGTTTTTCATTTACTAGTA
GTCATAATGTCGGTATAAAA

Product: anion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSEKKLDSHLPNDGNEYLFTDTFPKGTGKGLIVVAIAAVISLFIYNVLPYDISANKGLAMLFFIGVLWLTEAVHVTITAI
LVVVVGALIGLPDFDAEIGLQSFANPIIYLFFGGFALAAALHVQQLDRKIALKILSMSGGNLRNAVFLIFGVTAFLSMWI
SNTATAAMMLPLALGILTQVDREKDRGTFVFVLLGIAYSASLGGLGTIVGSPPNAIAAKALDIAFVDWMKFGIPMMLVLL
PLLLGAMYLFLKPNLNRQVTLNEDDEAIAWNKPRVLTIIVFIVTALSWILSKQIGAALNIADVDSIVALLAASAVVSLGL
VSWKQVSDNTDWGVLMLFGGGIALSTVLKVSGASLVLGQAVANGLSSAPLIVVVLAVAAFIIFLTEFASNTASAALLVPV
FAAIAEQMGLPPAVLVMIIGIGASCAFMLPVATPPNAIVFGTGLIKQTEMIRVGVILNVISTFIIGLWAYFFLL

Sequences:

>Translated_474_residues
MSEKKLDSHLPNDGNEYLFTDTFPKGTGKGLIVVAIAAVISLFIYNVLPYDISANKGLAMLFFIGVLWLTEAVHVTITAI
LVVVVGALIGLPDFDAEIGLQSFANPIIYLFFGGFALAAALHVQQLDRKIALKILSMSGGNLRNAVFLIFGVTAFLSMWI
SNTATAAMMLPLALGILTQVDREKDRGTFVFVLLGIAYSASLGGLGTIVGSPPNAIAAKALDIAFVDWMKFGIPMMLVLL
PLLLGAMYLFLKPNLNRQVTLNEDDEAIAWNKPRVLTIIVFIVTALSWILSKQIGAALNIADVDSIVALLAASAVVSLGL
VSWKQVSDNTDWGVLMLFGGGIALSTVLKVSGASLVLGQAVANGLSSAPLIVVVLAVAAFIIFLTEFASNTASAALLVPV
FAAIAEQMGLPPAVLVMIIGIGASCAFMLPVATPPNAIVFGTGLIKQTEMIRVGVILNVISTFIIGLWAYFFLL
>Mature_473_residues
SEKKLDSHLPNDGNEYLFTDTFPKGTGKGLIVVAIAAVISLFIYNVLPYDISANKGLAMLFFIGVLWLTEAVHVTITAIL
VVVVGALIGLPDFDAEIGLQSFANPIIYLFFGGFALAAALHVQQLDRKIALKILSMSGGNLRNAVFLIFGVTAFLSMWIS
NTATAAMMLPLALGILTQVDREKDRGTFVFVLLGIAYSASLGGLGTIVGSPPNAIAAKALDIAFVDWMKFGIPMMLVLLP
LLLGAMYLFLKPNLNRQVTLNEDDEAIAWNKPRVLTIIVFIVTALSWILSKQIGAALNIADVDSIVALLAASAVVSLGLV
SWKQVSDNTDWGVLMLFGGGIALSTVLKVSGASLVLGQAVANGLSSAPLIVVVLAVAAFIIFLTEFASNTASAALLVPVF
AAIAEQMGLPPAVLVMIIGIGASCAFMLPVATPPNAIVFGTGLIKQTEMIRVGVILNVISTFIIGLWAYFFLL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=503, Percent_Identity=27.6341948310139, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI225637552, Length=470, Percent_Identity=28.936170212766, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI225637549, Length=470, Percent_Identity=28.936170212766, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI301069349, Length=351, Percent_Identity=27.9202279202279, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI19923838, Length=339, Percent_Identity=26.5486725663717, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI31377715, Length=148, Percent_Identity=35.8108108108108, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI301069353, Length=148, Percent_Identity=35.8108108108108, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI58761541, Length=148, Percent_Identity=35.8108108108108, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI301069346, Length=148, Percent_Identity=35.8108108108108, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4506979, Length=150, Percent_Identity=38.6666666666667, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI31795546, Length=351, Percent_Identity=24.7863247863248, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI219802232, Length=464, Percent_Identity=24.5689655172414, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1786829, Length=398, Percent_Identity=24.8743718592965, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17551790, Length=507, Percent_Identity=26.0355029585799, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71988385, Length=481, Percent_Identity=27.6507276507277, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32565804, Length=448, Percent_Identity=28.5714285714286, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71989118, Length=507, Percent_Identity=27.0216962524655, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32564681, Length=504, Percent_Identity=25.3968253968254, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324340, Length=417, Percent_Identity=23.2613908872902, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319885, Length=455, Percent_Identity=24.1758241758242, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322263, Length=399, Percent_Identity=23.8095238095238, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706796, Length=492, Percent_Identity=26.6260162601626, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI78706798, Length=492, Percent_Identity=26.6260162601626, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45551633, Length=218, Percent_Identity=26.605504587156, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI281366409, Length=218, Percent_Identity=26.605504587156, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17737623, Length=218, Percent_Identity=26.605504587156, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24666468, Length=218, Percent_Identity=26.605504587156, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281362114, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362112, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362116, Length=234, Percent_Identity=27.3504273504274, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50113; Mature: 49981

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKLDSHLPNDGNEYLFTDTFPKGTGKGLIVVAIAAVISLFIYNVLPYDISANKGLAM
CCCCCCHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LFFIGVLWLTEAVHVTITAILVVVVGALIGLPDFDAEIGLQSFANPIIYLFFGGFALAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHCCHHHHHHHHHHHHHHH
LHVQQLDRKIALKILSMSGGNLRNAVFLIFGVTAFLSMWISNTATAAMMLPLALGILTQV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DREKDRGTFVFVLLGIAYSASLGGLGTIVGSPPNAIAAKALDIAFVDWMKFGIPMMLVLL
HCCCCCCCEEHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLLGAMYLFLKPNLNRQVTLNEDDEAIAWNKPRVLTIIVFIVTALSWILSKQIGAALNI
HHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEECH
ADVDSIVALLAASAVVSLGLVSWKQVSDNTDWGVLMLFGGGIALSTVLKVSGASLVLGQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHH
VANGLSSAPLIVVVLAVAAFIIFLTEFASNTASAALLVPVFAAIAEQMGLPPAVLVMIIG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IGASCAFMLPVATPPNAIVFGTGLIKQTEMIRVGVILNVISTFIIGLWAYFFLL
CCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SEKKLDSHLPNDGNEYLFTDTFPKGTGKGLIVVAIAAVISLFIYNVLPYDISANKGLAM
CCCCCHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LFFIGVLWLTEAVHVTITAILVVVVGALIGLPDFDAEIGLQSFANPIIYLFFGGFALAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHCCHHHHHHHHHHHHHHH
LHVQQLDRKIALKILSMSGGNLRNAVFLIFGVTAFLSMWISNTATAAMMLPLALGILTQV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DREKDRGTFVFVLLGIAYSASLGGLGTIVGSPPNAIAAKALDIAFVDWMKFGIPMMLVLL
HCCCCCCCEEHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLLGAMYLFLKPNLNRQVTLNEDDEAIAWNKPRVLTIIVFIVTALSWILSKQIGAALNI
HHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEECH
ADVDSIVALLAASAVVSLGLVSWKQVSDNTDWGVLMLFGGGIALSTVLKVSGASLVLGQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHH
VANGLSSAPLIVVVLAVAAFIIFLTEFASNTASAALLVPVFAAIAEQMGLPPAVLVMIIG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IGASCAFMLPVATPPNAIVFGTGLIKQTEMIRVGVILNVISTFIIGLWAYFFLL
CCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]