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The map label for this gene is nadR [C]

Identifier: 93006240

GI number: 93006240

Start: 1736562

End: 1737170

Strand: Direct

Name: nadR [C]

Synonym: Pcryo_1414

Alternate gene names: 93006240

Gene position: 1736562-1737170 (Clockwise)

Preceding gene: 93006239

Following gene: 93006242

Centisome position: 56.75

GC content: 42.86

Gene sequence:

>609_bases
ATGAATGGCAACAACGCTACCGCCTTCAATCTCACGCAGCATACGCCTAAATCCGTCATCAAGGTCGCAGTTTTAGGCGC
AGAAAGTACGGGAAAAACCACACTGTGCCGTGATTTAGCTACCCATTTTGGCTGTCCTTGGGTGCCAGAGTATATGCGCA
CTTACTTGCAAGCTAAATGGGACGACGAGCAACTGACCTGTACGTGGGAGGATTTGCTACCTATTGCACAAGGTCAGATA
CTGCTTGAGAATAAGTTGGCAAAGCAAGTATCACAAACGTCAAACGACCATCATTATTTATTTTGTGATACCAGCTTGTT
TGAACTGATGGTTTATTCCAATTGGTATTATGGCGATTGCCCTGAAACGCTTACCCAAGCAGCATTGGTACATCATTATG
ACTTAATACTATTAACCGACGTTGATACACCTTGGGTTGCTGATGACTTGCGTGATAGCCCACATCAGCGCGATGAAATA
AGCGCTTATTTTGCTGATCAGTTAACAGCTTATAACAAACCATTTCAATCAATTGGTGGTGATAGAGAGGTGCGGGTTCA
ACAAGTGATAAAATTGCTAGACGCATCTGAATTAAATAATAATGCTTAG

Upstream 100 bases:

>100_bases
GTCGCTGATGCTATCTCAGTACCGCTCTATTTTTATAAAGGTCTAACCTTTACAGCATTACAATACGTAGTCTTCACTCT
CATCGCAATTTGGGCTTATT

Downstream 100 bases:

>100_bases
GCTATTTAATAAACACTGTCAAACCTTGCACCCATTACTACCTCACGAGCTTAGTGTTTAAAGCTTTTGCCCAATTCCGG
CAGTTATCTTCACAGCGCTC

Product: NadR-like protein

Products: NAD; pyrophosphate [C]

Alternate protein names: ATPase/Kinase Involved In NAD Metabolism-Like Protein; NADR-Like Protein; Transcriptional Regulatory Protein NADR; Cytidyltransferase-Related Domain Protein; ATPase/Kinase Involved In NAD Metabolism; NAD Metabolism ATPase/Kinase; Transcriptional Regulatory Protein NADr; NADR-Like Transcriptional Regulator; Cytidyltransferase-Related; Transcriptional Regulator; Transcriptional Regulator NADR; Transcriptional Regulatory Protein; Cytidylyltransferase; Transcription Regulator NADR; Cytidyltransferase-Related Domain-Containing Protein; ATPase/Kinase NadR; NAD Metabolism ATPase/Kinase-Like Protein; NADR Family Transcriptional Regulator; NAD Metabolism Atpase/Kinase-Like Protein

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MNGNNATAFNLTQHTPKSVIKVAVLGAESTGKTTLCRDLATHFGCPWVPEYMRTYLQAKWDDEQLTCTWEDLLPIAQGQI
LLENKLAKQVSQTSNDHHYLFCDTSLFELMVYSNWYYGDCPETLTQAALVHHYDLILLTDVDTPWVADDLRDSPHQRDEI
SAYFADQLTAYNKPFQSIGGDREVRVQQVIKLLDASELNNNA

Sequences:

>Translated_202_residues
MNGNNATAFNLTQHTPKSVIKVAVLGAESTGKTTLCRDLATHFGCPWVPEYMRTYLQAKWDDEQLTCTWEDLLPIAQGQI
LLENKLAKQVSQTSNDHHYLFCDTSLFELMVYSNWYYGDCPETLTQAALVHHYDLILLTDVDTPWVADDLRDSPHQRDEI
SAYFADQLTAYNKPFQSIGGDREVRVQQVIKLLDASELNNNA
>Mature_202_residues
MNGNNATAFNLTQHTPKSVIKVAVLGAESTGKTTLCRDLATHFGCPWVPEYMRTYLQAKWDDEQLTCTWEDLLPIAQGQI
LLENKLAKQVSQTSNDHHYLFCDTSLFELMVYSNWYYGDCPETLTQAALVHHYDLILLTDVDTPWVADDLRDSPHQRDEI
SAYFADQLTAYNKPFQSIGGDREVRVQQVIKLLDASELNNNA

Specific function: NADr Is Bifunctional; It Interacts With Pnuc At Low Internal NAD Levels, Permitting Transport Of Nmn Intact Into The Cell. As NAD Levels Increase Within The Cell, The Affinity Of NADr For The Operator Regions Of NADa, NADb, And Pncb Increases, Repressing

COG id: COG3172

COG function: function code H; Predicted ATPase/kinase involved in NAD metabolism

Gene ontology:

Cell location: May Loosely Associate With The Membrane Through Its Interaction With The Membrane-Bound Pnuc [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 22959; Mature: 22959

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNNATAFNLTQHTPKSVIKVAVLGAESTGKTTLCRDLATHFGCPWVPEYMRTYLQAKW
CCCCCCEEEEECCCCHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCC
DDEQLTCTWEDLLPIAQGQILLENKLAKQVSQTSNDHHYLFCDTSLFELMVYSNWYYGDC
CCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCCC
PETLTQAALVHHYDLILLTDVDTPWVADDLRDSPHQRDEISAYFADQLTAYNKPFQSIGG
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHCCC
DREVRVQQVIKLLDASELNNNA
CCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNGNNATAFNLTQHTPKSVIKVAVLGAESTGKTTLCRDLATHFGCPWVPEYMRTYLQAKW
CCCCCCEEEEECCCCHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCC
DDEQLTCTWEDLLPIAQGQILLENKLAKQVSQTSNDHHYLFCDTSLFELMVYSNWYYGDC
CCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCCC
PETLTQAALVHHYDLILLTDVDTPWVADDLRDSPHQRDEISAYFADQLTAYNKPFQSIGG
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHCCC
DREVRVQQVIKLLDASELNNNA
CCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide; ATP [C]

Specific reaction: nicotinamide nucleotide + ATP = NAD + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA