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The map label for this gene is fabH [H]

Identifier: 93006238

GI number: 93006238

Start: 1734393

End: 1735538

Strand: Reverse

Name: fabH [H]

Synonym: Pcryo_1412

Alternate gene names: 93006238

Gene position: 1735538-1734393 (Counterclockwise)

Preceding gene: 93006241

Following gene: 93006237

Centisome position: 56.72

GC content: 43.54

Gene sequence:

>1146_bases
ATGACGACTTGTATCACAGGCACCGGCCTGTATATCCCGCCTTTTAGCATCAGTAATGAAGAACTGGTAGAGTCCTTTAA
TCAGTATGTTGAAAAATATAATACAAAACATGCGGCTGACATTGAAGCAGGCACACTCACGGCTCTTCAACCTTCATCAG
CGGCTTTTATCGAAAAAGTATCTGGTATCAAATCACGCTATGTGATGGAAAAAGACGGCATCTTAAATCCTGACATCATG
GCACCTGTTATCGCTTATCGTAACTTGGGCGAAGAGCTGTCTATCATGGCAGAAATGGGTGTGGCCGCGTTAAATGATGC
CTTGGCTGATGCAGGACTTGAGGCCAATGATTTAGATGGTATCATCCTTGCCTGCTCAAACTTTCAGCGTACTTATCCAG
CTGTCTCTATCGAGATTCAAAATGCGATCGGTATGGTGGGCGGCTTTGCTTATGATATGAATGTAGCTTGTAGTGCCGCA
ACTTTTGGTCTATCACAAGCACATGGTTCTATCGCATCAGGTCTTGCTAAGCGCGTCGCTGTGGTCAACGTTGAAATTAC
TTCAGCGCATCTAAACTGGCGTAACCGTGACAGTCACTTTATCTTTGGTGATGTCGCAACCGCTTGTATTGTCGAAGAAC
TCGATACGCCTAAAGGCTATGAGATTTTAAACTCTAAGCTATTTACTCAGTTTTCGACCAATATCAAAAACGAATACGGT
TTTATGGATCGCTCAGAGTTTTTGGCCGCGCAAACAGAGATGTATCCGGATATTAAAGAGCCAGTAACCGATAAATTATT
CTTACAAAATGGTCGTAAAGTCTTCCGTGAAGTCTGTCCAAAAGTGTCAGAAGTCATTACTGAGCATCTACAAGAGAATA
ACATCGCAACCTCTGATGTAAAAATGATGTGGCTCCATCAAGCCAATGCCAACATGCTAGATTTAATCTTGCGTACGGTC
ATCGGTAAAGAAGCAGACAAAGCCATTGTACCGAGTGTCATTGCTGAATTCGCCAATACCAGCTCAGCAAGCCCAATGAT
TGTTTTCCATCGCTATAAAGATGACCTTGCATCCGGTGATTTGGGTGTTATTTGCTCGTTTGGTGCTGGTTACTCTATTG
GGTCGGTAATCGTCCGCAAGGTCTAA

Upstream 100 bases:

>100_bases
ATTTTAAGTTTACAGTCATTCACCCAAAATTAGACGACTGTTGTTTTACTTCACCTTATGCTTATTTCAAGCACCATAGT
AGTAGACAAGGAAGCGTATC

Downstream 100 bases:

>100_bases
TTTTTTTAAGCCTTGAGTCTTAATTATTATCAAAATAGTCAAGAATATTCTTGGCTATTTTTTTATTTAAATTTTAAGGG
AAGCTGATGCTGCATTCAAA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTTCITGTGLYIPPFSISNEELVESFNQYVEKYNTKHAADIEAGTLTALQPSSAAFIEKVSGIKSRYVMEKDGILNPDIM
APVIAYRNLGEELSIMAEMGVAALNDALADAGLEANDLDGIILACSNFQRTYPAVSIEIQNAIGMVGGFAYDMNVACSAA
TFGLSQAHGSIASGLAKRVAVVNVEITSAHLNWRNRDSHFIFGDVATACIVEELDTPKGYEILNSKLFTQFSTNIKNEYG
FMDRSEFLAAQTEMYPDIKEPVTDKLFLQNGRKVFREVCPKVSEVITEHLQENNIATSDVKMMWLHQANANMLDLILRTV
IGKEADKAIVPSVIAEFANTSSASPMIVFHRYKDDLASGDLGVICSFGAGYSIGSVIVRKV

Sequences:

>Translated_381_residues
MTTCITGTGLYIPPFSISNEELVESFNQYVEKYNTKHAADIEAGTLTALQPSSAAFIEKVSGIKSRYVMEKDGILNPDIM
APVIAYRNLGEELSIMAEMGVAALNDALADAGLEANDLDGIILACSNFQRTYPAVSIEIQNAIGMVGGFAYDMNVACSAA
TFGLSQAHGSIASGLAKRVAVVNVEITSAHLNWRNRDSHFIFGDVATACIVEELDTPKGYEILNSKLFTQFSTNIKNEYG
FMDRSEFLAAQTEMYPDIKEPVTDKLFLQNGRKVFREVCPKVSEVITEHLQENNIATSDVKMMWLHQANANMLDLILRTV
IGKEADKAIVPSVIAEFANTSSASPMIVFHRYKDDLASGDLGVICSFGAGYSIGSVIVRKV
>Mature_380_residues
TTCITGTGLYIPPFSISNEELVESFNQYVEKYNTKHAADIEAGTLTALQPSSAAFIEKVSGIKSRYVMEKDGILNPDIMA
PVIAYRNLGEELSIMAEMGVAALNDALADAGLEANDLDGIILACSNFQRTYPAVSIEIQNAIGMVGGFAYDMNVACSAAT
FGLSQAHGSIASGLAKRVAVVNVEITSAHLNWRNRDSHFIFGDVATACIVEELDTPKGYEILNSKLFTQFSTNIKNEYGF
MDRSEFLAAQTEMYPDIKEPVTDKLFLQNGRKVFREVCPKVSEVITEHLQENNIATSDVKMMWLHQANANMLDLILRTVI
GKEADKAIVPSVIAEFANTSSASPMIVFHRYKDDLASGDLGVICSFGAGYSIGSVIVRKV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=341, Percent_Identity=26.099706744868, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41485; Mature: 41354

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTCITGTGLYIPPFSISNEELVESFNQYVEKYNTKHAADIEAGTLTALQPSSAAFIEKV
CCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHH
SGIKSRYVMEKDGILNPDIMAPVIAYRNLGEELSIMAEMGVAALNDALADAGLEANDLDG
HHHHHHEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IILACSNFQRTYPAVSIEIQNAIGMVGGFAYDMNVACSAATFGLSQAHGSIASGLAKRVA
EEEEECCCCCCCCEEEEEEHHHHHHHHCEEEECCCCHHHHHHCHHHHHHHHHHHHHHHEE
VVNVEITSAHLNWRNRDSHFIFGDVATACIVEELDTPKGYEILNSKLFTQFSTNIKNEYG
EEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHCC
FMDRSEFLAAQTEMYPDIKEPVTDKLFLQNGRKVFREVCPKVSEVITEHLQENNIATSDV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KMMWLHQANANMLDLILRTVIGKEADKAIVPSVIAEFANTSSASPMIVFHRYKDDLASGD
EEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHCCCCC
LGVICSFGAGYSIGSVIVRKV
CEEEEECCCCCCHHHHHHCCC
>Mature Secondary Structure 
TTCITGTGLYIPPFSISNEELVESFNQYVEKYNTKHAADIEAGTLTALQPSSAAFIEKV
CEEEECCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHH
SGIKSRYVMEKDGILNPDIMAPVIAYRNLGEELSIMAEMGVAALNDALADAGLEANDLDG
HHHHHHEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IILACSNFQRTYPAVSIEIQNAIGMVGGFAYDMNVACSAATFGLSQAHGSIASGLAKRVA
EEEEECCCCCCCCEEEEEEHHHHHHHHCEEEECCCCHHHHHHCHHHHHHHHHHHHHHHEE
VVNVEITSAHLNWRNRDSHFIFGDVATACIVEELDTPKGYEILNSKLFTQFSTNIKNEYG
EEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHCC
FMDRSEFLAAQTEMYPDIKEPVTDKLFLQNGRKVFREVCPKVSEVITEHLQENNIATSDV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KMMWLHQANANMLDLILRTVIGKEADKAIVPSVIAEFANTSSASPMIVFHRYKDDLASGD
EEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHCCCCC
LGVICSFGAGYSIGSVIVRKV
CEEEEECCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA