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The map label for this gene is argD [H]

Identifier: 93006231

GI number: 93006231

Start: 1724812

End: 1725993

Strand: Direct

Name: argD [H]

Synonym: Pcryo_1405

Alternate gene names: 93006231

Gene position: 1724812-1725993 (Clockwise)

Preceding gene: 93006230

Following gene: 93006239

Centisome position: 56.37

GC content: 45.43

Gene sequence:

>1182_bases
ATGTCTGCTACTTACCTGATGCCCACTTATCTTCGTCAACCTATCAGTTTTACCCGCGGCTCAGGAAGCTGGCTCTATAC
TCAAGATGAGACGCCTTATCTAGACGCATTGACTGGTATCGCGGTATGTGGTTTAGGACATTGCCATCCACAAGTAACCG
AAGCTATTCAACAGCAGGCAGCAACATTGGTTCATACCAGTAATTTATTTGGTATAGACTGGCAAGAGCGTGCTGGTGAA
GCATTATGTAATGCCGCGCAAATGGACAGTGTATTTTTTGCCAATAGTGGCGCTGAAGCAAATGAAGCAGCACTAAAATT
GGCGCGTCTATACGCACATCAACAGGGTTTTAAGCGTCCAAAAGTCATTGTGATGGAGCAATCTTTCCATGGTCGTACCT
TATTATCATTATCAGCAACTGCCAACCCCAAAGCGCGCGAAGGCTTTTACACTTTAGATAATGATTTTATCCGTGTGCCA
TTTGGGGATATTGCCGCCATTAAACAAGCAGCTCATGACTATGAGGATATTTGCGCGGTATTCGTAGAGCCTATTCAAGG
TGAAGGTGGTCTTAATACGGCAGCTAACGGCTTTACTTACCTTGAGCAGATACAAGCCGTATGCGATACACATAATTGGC
TGTTCATGCTTGATGAAGTACAGACAGGCAATGGACGAACAGGTAAGTATTTTGCTTATCAGCATAGCAGCGCACGCCCT
GATGTATTAACGACGGCTAAAGGCTTAGGTAATGGCTTTCCTGTCGGTGCCTGTATGGTACGTGGTCGCGCTAATGGCTT
ATTTGGAGCTGGTAGTCATGGCTCAACCTATGGTGGTACACCGTTAGCCAGTCGTGTGGTACATAGCGTATATGACGTAT
TGGCGAACAGTGATATCATGCAAAACGCCGTCAACGAGGGACAGTTTATTCGTGATAGCATGGTTGATGCATTTGGACAA
TATGGCGTCAGCAGTCGCGGCGCTGGGATGATGATTGGCATTGCCCTACCAGAAGACATGGACTGTAGCAAGCTTGTCGA
TCGTGCTCGTGATGAGCAGAAACTTATCATCAATGTTACAGGCGGTCATGTAATTCGTTTGCTACCACCACTTAATATGA
GCCGTAATGAAAGCTCACAAGTAGTTGAACGCTTGGTTAATTTACTAAAACCTTCGTTTTAA

Upstream 100 bases:

>100_bases
ATACATTGCCTGCTGAGTCGACGCCGTTTTCTGATGAGCTATAACATTAAGCGCTTTACCCTCTTACTTTTATCACTTTA
TGATTCCAAGGATGCTGTAC

Downstream 100 bases:

>100_bases
ACGTCTATTTAACCAAAATATAAAAAGCCTATAGATAAATTATCTATAGGCTTTTTTCATTATTAATCATTCAGCTTTGT
TAGCATTTAAATAAACTAAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSATYLMPTYLRQPISFTRGSGSWLYTQDETPYLDALTGIAVCGLGHCHPQVTEAIQQQAATLVHTSNLFGIDWQERAGE
ALCNAAQMDSVFFANSGAEANEAALKLARLYAHQQGFKRPKVIVMEQSFHGRTLLSLSATANPKAREGFYTLDNDFIRVP
FGDIAAIKQAAHDYEDICAVFVEPIQGEGGLNTAANGFTYLEQIQAVCDTHNWLFMLDEVQTGNGRTGKYFAYQHSSARP
DVLTTAKGLGNGFPVGACMVRGRANGLFGAGSHGSTYGGTPLASRVVHSVYDVLANSDIMQNAVNEGQFIRDSMVDAFGQ
YGVSSRGAGMMIGIALPEDMDCSKLVDRARDEQKLIINVTGGHVIRLLPPLNMSRNESSQVVERLVNLLKPSF

Sequences:

>Translated_393_residues
MSATYLMPTYLRQPISFTRGSGSWLYTQDETPYLDALTGIAVCGLGHCHPQVTEAIQQQAATLVHTSNLFGIDWQERAGE
ALCNAAQMDSVFFANSGAEANEAALKLARLYAHQQGFKRPKVIVMEQSFHGRTLLSLSATANPKAREGFYTLDNDFIRVP
FGDIAAIKQAAHDYEDICAVFVEPIQGEGGLNTAANGFTYLEQIQAVCDTHNWLFMLDEVQTGNGRTGKYFAYQHSSARP
DVLTTAKGLGNGFPVGACMVRGRANGLFGAGSHGSTYGGTPLASRVVHSVYDVLANSDIMQNAVNEGQFIRDSMVDAFGQ
YGVSSRGAGMMIGIALPEDMDCSKLVDRARDEQKLIINVTGGHVIRLLPPLNMSRNESSQVVERLVNLLKPSF
>Mature_392_residues
SATYLMPTYLRQPISFTRGSGSWLYTQDETPYLDALTGIAVCGLGHCHPQVTEAIQQQAATLVHTSNLFGIDWQERAGEA
LCNAAQMDSVFFANSGAEANEAALKLARLYAHQQGFKRPKVIVMEQSFHGRTLLSLSATANPKAREGFYTLDNDFIRVPF
GDIAAIKQAAHDYEDICAVFVEPIQGEGGLNTAANGFTYLEQIQAVCDTHNWLFMLDEVQTGNGRTGKYFAYQHSSARPD
VLTTAKGLGNGFPVGACMVRGRANGLFGAGSHGSTYGGTPLASRVVHSVYDVLANSDIMQNAVNEGQFIRDSMVDAFGQY
GVSSRGAGMMIGIALPEDMDCSKLVDRARDEQKLIINVTGGHVIRLLPPLNMSRNESSQVVERLVNLLKPSF

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=376, Percent_Identity=32.1808510638298, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI284507298, Length=295, Percent_Identity=33.8983050847458, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI13994255, Length=426, Percent_Identity=27.4647887323944, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=26.9689737470167, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=26.378896882494, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=26.6839378238342, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=25.5980861244019, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI188536080, Length=413, Percent_Identity=24.2130750605327, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679950, Length=413, Percent_Identity=24.2130750605327, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679946, Length=413, Percent_Identity=24.2130750605327, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788044, Length=385, Percent_Identity=38.7012987012987, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=38.5204081632653, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI145693181, Length=386, Percent_Identity=32.1243523316062, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=31.0344827586207, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787560, Length=370, Percent_Identity=29.7297297297297, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786991, Length=343, Percent_Identity=28.2798833819242, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786349, Length=310, Percent_Identity=26.4516129032258, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25144271, Length=382, Percent_Identity=31.151832460733, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=29.3981481481481, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=28.8056206088993, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25144274, Length=290, Percent_Identity=31.0344827586207, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=30.379746835443, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71992985, Length=121, Percent_Identity=35.5371900826446, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=386, Percent_Identity=34.1968911917098, Blast_Score=202, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6323470, Length=407, Percent_Identity=30.2211302211302, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6324386, Length=335, Percent_Identity=25.6716417910448, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321456, Length=438, Percent_Identity=21.4611872146119, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357415, Length=375, Percent_Identity=31.7333333333333, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI28574759, Length=432, Percent_Identity=28.0092592592593, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI161085790, Length=437, Percent_Identity=27.9176201372998, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=27.6442307692308, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=24.3055555555556, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=24.3055555555556, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=24.3055555555556, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42672; Mature: 42541

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATYLMPTYLRQPISFTRGSGSWLYTQDETPYLDALTGIAVCGLGHCHPQVTEAIQQQA
CCCCEECHHHHHCCCCEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ATLVHTSNLFGIDWQERAGEALCNAAQMDSVFFANSGAEANEAALKLARLYAHQQGFKRP
HHHHEECCEECCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
KVIVMEQSFHGRTLLSLSATANPKAREGFYTLDNDFIRVPFGDIAAIKQAAHDYEDICAV
EEEEEECCCCCCEEEEEECCCCCCCCCCCEEECCCEEECCCHHHHHHHHHHCCHHHHHHH
FVEPIQGEGGLNTAANGFTYLEQIQAVCDTHNWLFMLDEVQTGNGRTGKYFAYQHSSARP
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCC
DVLTTAKGLGNGFPVGACMVRGRANGLFGAGSHGSTYGGTPLASRVVHSVYDVLANSDIM
CHHHHHHHCCCCCCHHHEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
QNAVNEGQFIRDSMVDAFGQYGVSSRGAGMMIGIALPEDMDCSKLVDRARDEQKLIINVT
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEC
GGHVIRLLPPLNMSRNESSQVVERLVNLLKPSF
CCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SATYLMPTYLRQPISFTRGSGSWLYTQDETPYLDALTGIAVCGLGHCHPQVTEAIQQQA
CCCEECHHHHHCCCCEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ATLVHTSNLFGIDWQERAGEALCNAAQMDSVFFANSGAEANEAALKLARLYAHQQGFKRP
HHHHEECCEECCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
KVIVMEQSFHGRTLLSLSATANPKAREGFYTLDNDFIRVPFGDIAAIKQAAHDYEDICAV
EEEEEECCCCCCEEEEEECCCCCCCCCCCEEECCCEEECCCHHHHHHHHHHCCHHHHHHH
FVEPIQGEGGLNTAANGFTYLEQIQAVCDTHNWLFMLDEVQTGNGRTGKYFAYQHSSARP
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCC
DVLTTAKGLGNGFPVGACMVRGRANGLFGAGSHGSTYGGTPLASRVVHSVYDVLANSDIM
CHHHHHHHCCCCCCHHHEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
QNAVNEGQFIRDSMVDAFGQYGVSSRGAGMMIGIALPEDMDCSKLVDRARDEQKLIINVT
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEC
GGHVIRLLPPLNMSRNESSQVVERLVNLLKPSF
CCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]