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The map label for this gene is ubiB [C]

Identifier: 93006228

GI number: 93006228

Start: 1722035

End: 1723522

Strand: Direct

Name: ubiB [C]

Synonym: Pcryo_1402

Alternate gene names: 93006228

Gene position: 1722035-1723522 (Clockwise)

Preceding gene: 93006227

Following gene: 93006230

Centisome position: 56.28

GC content: 41.4

Gene sequence:

>1488_bases
ATGATACAATTCTGTACACTCATAGCACATCTCCCTTGTATTGTAGGTACATCACCCACAAATCAATACCAACTCGATGA
AATGACGATATCTATGGCAAACAATACCTCTAGGTCTTCTAATAACAAGCAGTCTATCGATAATTTAAAAACATCGGGGT
TTGATCGTCGTATGTCGATTGCCAAAACCTCATTGAACATTGGTCGACGTTGGGCAGGTAATAGCGTGTCTGGTATGTTT
CTTAATAAAGAAGCACGTACAGCACGTAACCAGATTTTTATGGAAGAACAGGCGCATTATTTGGCAGAAGAGCTTGGTAA
ATTAAAAGGCTCTGTCGTGAAAATTGGTCAAATGCTAGCGATTTATGGTGAGCATATCTTACCACCTGAGATTACCCGTG
CCTTACAAACGCTTAATGATGATACAGCGACACTTGCATGGCCAAAAATCGAGCAGAATTTACAGGATTTATTGGGTAAT
AAGCTGCAGGATCTTCAGGTTGACCCTGTCCCTATTGGTACAGCATCCCTCGCCCAAGTTCACCGTGCAACCGTCATAGC
CACGGGTGAGCAAGTGGTATTAAAGATTCAATATCCGGGTGTAGCTGATGCGATTAACTCTGATTTGGCTCTATTTAAGA
GCCTATTAAAGGTTAGTAATATCGTTCCACAAACCCGTTCACTCGATGCATGGTTTGAAGAGATACGTGATTTATTACAT
CATGAAGTCGACTATGAGGCGGAAGCTGACACAACAGAGCGGTTCTATAACCGTTTGATTGACGATGCACGTTATGTTGT
ACCGAGAATTAACCGCCATTATTCGACCAAGCGCTTACTTTGTATGTCTTATGAGCCGGGTATCAGTGTGGTTTCTGACG
CATTGCAACTACTCCCTCTTGAGCGTCGAAACGCCATCGGTCAGGCGGCTATCGAAATCATGATACAAGAGATTTTCGTT
TGGGGTGAGATGCAAACGGATCCAAACTTTGGTAATTACCTTGTCCGTGTCGCACGCGACGAAACTGAAATTGATAAACT
GGTCTTATTAGATTTTGGTGCGATTCGCCAGTTCGATAACAACTTATTGACGATTGCTCATAATTTATTACGTTCCGGTT
ATTATCATGATCATCAATCTATGATGAGTGCCATGACTGGTTATGACTTTTTTGATACCATGAGTGATAAAGTACGTTCA
GATATCGCCTCATTGTTTTTGTTGGCAACTGAACCTTTTAGTGAGCCTGTGATAAACACTGATATGCCTGCTAATTGTCT
AGATGACCAACAGCGCTATATTTGGGCTAACAGTAAGCTGCATACTCGCCTCTCAAATGATGCGACACAAGCGATGCAGT
CTTTCGAGTTCAATCTACCACCTAAAGAGTTTATGTTTATCAGTCGGAAATTTATCGGTGCCTATACTTTTTTGACTGTG
CTTGATGCTCGTACGGATTCTAATAATTTAGTAAAACCGTTTTTATAA

Upstream 100 bases:

>100_bases
AAACTAACAGGCAAAAAATGCTTAAGAATTTCAGTATGCTAGCCTAAATTACAAAGTAAATAACGTCGCTTGGCTAAGCT
GCAAAACCTGCCTTCTTTAT

Downstream 100 bases:

>100_bases
ACTTATTTTAACGTACTTACTCGACGGATTTTTGAACTGCCTTTCTGGGGCGGTTTTATTTATTACAATCTTAATTGCTT
AGGCTATTTTATAGTTTTAA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MIQFCTLIAHLPCIVGTSPTNQYQLDEMTISMANNTSRSSNNKQSIDNLKTSGFDRRMSIAKTSLNIGRRWAGNSVSGMF
LNKEARTARNQIFMEEQAHYLAEELGKLKGSVVKIGQMLAIYGEHILPPEITRALQTLNDDTATLAWPKIEQNLQDLLGN
KLQDLQVDPVPIGTASLAQVHRATVIATGEQVVLKIQYPGVADAINSDLALFKSLLKVSNIVPQTRSLDAWFEEIRDLLH
HEVDYEAEADTTERFYNRLIDDARYVVPRINRHYSTKRLLCMSYEPGISVVSDALQLLPLERRNAIGQAAIEIMIQEIFV
WGEMQTDPNFGNYLVRVARDETEIDKLVLLDFGAIRQFDNNLLTIAHNLLRSGYYHDHQSMMSAMTGYDFFDTMSDKVRS
DIASLFLLATEPFSEPVINTDMPANCLDDQQRYIWANSKLHTRLSNDATQAMQSFEFNLPPKEFMFISRKFIGAYTFLTV
LDARTDSNNLVKPFL

Sequences:

>Translated_495_residues
MIQFCTLIAHLPCIVGTSPTNQYQLDEMTISMANNTSRSSNNKQSIDNLKTSGFDRRMSIAKTSLNIGRRWAGNSVSGMF
LNKEARTARNQIFMEEQAHYLAEELGKLKGSVVKIGQMLAIYGEHILPPEITRALQTLNDDTATLAWPKIEQNLQDLLGN
KLQDLQVDPVPIGTASLAQVHRATVIATGEQVVLKIQYPGVADAINSDLALFKSLLKVSNIVPQTRSLDAWFEEIRDLLH
HEVDYEAEADTTERFYNRLIDDARYVVPRINRHYSTKRLLCMSYEPGISVVSDALQLLPLERRNAIGQAAIEIMIQEIFV
WGEMQTDPNFGNYLVRVARDETEIDKLVLLDFGAIRQFDNNLLTIAHNLLRSGYYHDHQSMMSAMTGYDFFDTMSDKVRS
DIASLFLLATEPFSEPVINTDMPANCLDDQQRYIWANSKLHTRLSNDATQAMQSFEFNLPPKEFMFISRKFIGAYTFLTV
LDARTDSNNLVKPFL
>Mature_495_residues
MIQFCTLIAHLPCIVGTSPTNQYQLDEMTISMANNTSRSSNNKQSIDNLKTSGFDRRMSIAKTSLNIGRRWAGNSVSGMF
LNKEARTARNQIFMEEQAHYLAEELGKLKGSVVKIGQMLAIYGEHILPPEITRALQTLNDDTATLAWPKIEQNLQDLLGN
KLQDLQVDPVPIGTASLAQVHRATVIATGEQVVLKIQYPGVADAINSDLALFKSLLKVSNIVPQTRSLDAWFEEIRDLLH
HEVDYEAEADTTERFYNRLIDDARYVVPRINRHYSTKRLLCMSYEPGISVVSDALQLLPLERRNAIGQAAIEIMIQEIFV
WGEMQTDPNFGNYLVRVARDETEIDKLVLLDFGAIRQFDNNLLTIAHNLLRSGYYHDHQSMMSAMTGYDFFDTMSDKVRS
DIASLFLLATEPFSEPVINTDMPANCLDDQQRYIWANSKLHTRLSNDATQAMQSFEFNLPPKEFMFISRKFIGAYTFLTV
LDARTDSNNLVKPFL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI27363457, Length=427, Percent_Identity=24.824355971897, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI34147522, Length=435, Percent_Identity=25.9770114942529, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI217416386, Length=343, Percent_Identity=26.2390670553936, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI40254938, Length=264, Percent_Identity=32.1969696969697, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI41393593, Length=249, Percent_Identity=31.7269076305221, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI217035081, Length=240, Percent_Identity=32.0833333333333, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565180, Length=473, Percent_Identity=27.2727272727273, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17559152, Length=262, Percent_Identity=30.1526717557252, Blast_Score=89, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321319, Length=447, Percent_Identity=27.0693512304251, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6323282, Length=262, Percent_Identity=24.4274809160305, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859849, Length=311, Percent_Identity=29.2604501607717, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI22024280, Length=271, Percent_Identity=30.9963099630996, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24662575, Length=257, Percent_Identity=26.4591439688716, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 56106; Mature: 56106

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFCTLIAHLPCIVGTSPTNQYQLDEMTISMANNTSRSSNNKQSIDNLKTSGFDRRMSI
CCHHHHHHHHHHHHCCCCCCCCEEEHHEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHH
AKTSLNIGRRWAGNSVSGMFLNKEARTARNQIFMEEQAHYLAEELGKLKGSVVKIGQMLA
HHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYGEHILPPEITRALQTLNDDTATLAWPKIEQNLQDLLGNKLQDLQVDPVPIGTASLAQV
HHCCCCCCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHH
HRATVIATGEQVVLKIQYPGVADAINSDLALFKSLLKVSNIVPQTRSLDAWFEEIRDLLH
HHHHEEEECCEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
HEVDYEAEADTTERFYNRLIDDARYVVPRINRHYSTKRLLCMSYEPGISVVSDALQLLPL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCC
ERRNAIGQAAIEIMIQEIFVWGEMQTDPNFGNYLVRVARDETEIDKLVLLDFGAIRQFDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
NLLTIAHNLLRSGYYHDHQSMMSAMTGYDFFDTMSDKVRSDIASLFLLATEPFSEPVINT
CHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DMPANCLDDQQRYIWANSKLHTRLSNDATQAMQSFEFNLPPKEFMFISRKFIGAYTFLTV
CCCCCHHCCCCCEEEECCCCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LDARTDSNNLVKPFL
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MIQFCTLIAHLPCIVGTSPTNQYQLDEMTISMANNTSRSSNNKQSIDNLKTSGFDRRMSI
CCHHHHHHHHHHHHCCCCCCCCEEEHHEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHH
AKTSLNIGRRWAGNSVSGMFLNKEARTARNQIFMEEQAHYLAEELGKLKGSVVKIGQMLA
HHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYGEHILPPEITRALQTLNDDTATLAWPKIEQNLQDLLGNKLQDLQVDPVPIGTASLAQV
HHCCCCCCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHH
HRATVIATGEQVVLKIQYPGVADAINSDLALFKSLLKVSNIVPQTRSLDAWFEEIRDLLH
HHHHEEEECCEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
HEVDYEAEADTTERFYNRLIDDARYVVPRINRHYSTKRLLCMSYEPGISVVSDALQLLPL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCC
ERRNAIGQAAIEIMIQEIFVWGEMQTDPNFGNYLVRVARDETEIDKLVLLDFGAIRQFDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
NLLTIAHNLLRSGYYHDHQSMMSAMTGYDFFDTMSDKVRSDIASLFLLATEPFSEPVINT
CHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DMPANCLDDQQRYIWANSKLHTRLSNDATQAMQSFEFNLPPKEFMFISRKFIGAYTFLTV
CCCCCHHCCCCCEEEECCCCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LDARTDSNNLVKPFL
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]