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The map label for this gene is pcaI [H]

Identifier: 93006090

GI number: 93006090

Start: 1533140

End: 1533832

Strand: Reverse

Name: pcaI [H]

Synonym: Pcryo_1262

Alternate gene names: 93006090

Gene position: 1533832-1533140 (Counterclockwise)

Preceding gene: 93006091

Following gene: 93006089

Centisome position: 50.13

GC content: 45.45

Gene sequence:

>693_bases
ATGATTAATAAAGCAGATAAAAATATCACTGACGTACTTAGTCAAATCAAAGATGGCGCTACCATCATGATTGGTGGCTT
CGGTACTGCAGGGCAACCAGCTGAACTCATTGATGGACTTATTAATTTAGGCGTAAAGGATTTGGTCATCATTAATAATA
ATGCCGGTAACGGCGACTATGGCCTTGCCAAGCTCTTAAAAACAGGTGCTGTGCGTAAAATCATTTGCTCTTTCCCGCGT
CAATCGGATTCTTGGGTATTTGATGAGCTTTATCATGCTGGCAAGATTGAGCTGGAGCTAGTACCACAGGGTAATTTGGC
TTGCCGTATTCAAGCAGCAGGTATGGGACTCGGTGCGGTATATACGCCCACAGGCTTTGGTACTTTACTCGCAGAAGGCA
AAGAGACTCGAGAAATCGATGGTAAAGACTATGTTCTTGAATATCCCATTAAGGCTGATTTTGCTTTAATCAAGGCGGAT
AAAGGCGATCGCTGGGGTAATTTAGTCTACCGCAAGTCTGCCCGTAACTTTGGTCCTATCATGGCAATGGCGGCTGATAT
TACTATCGCCCAAGTCTCCGAAACGGTTGAGCTTGGCGCGCTTGATCCTGAGCACATTATTACACCGGGTATCTTTGTGC
AGCATGTGGTGCAAATTCAGCCTGCTAGCACAGCAACTACAGCCACCGCTTAA

Upstream 100 bases:

>100_bases
TTACAAAAAATTTAAGTAGTGTCAGAGTAATGACTCAACCTGTACACCGCTTATCAATCTTAAAGACACTACCTCATATG
ACTTTTTATAGGATATAAAC

Downstream 100 bases:

>100_bases
TACTGCCAACTATAAGGAGCGTCATCATGAGCCATACTTCCTACACCGTTTTGACCCGCGATCAAATCGCTGAGCGCGCT
GCACAAGATATCCCAGATGG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MINKADKNITDVLSQIKDGATIMIGGFGTAGQPAELIDGLINLGVKDLVIINNNAGNGDYGLAKLLKTGAVRKIICSFPR
QSDSWVFDELYHAGKIELELVPQGNLACRIQAAGMGLGAVYTPTGFGTLLAEGKETREIDGKDYVLEYPIKADFALIKAD
KGDRWGNLVYRKSARNFGPIMAMAADITIAQVSETVELGALDPEHIITPGIFVQHVVQIQPASTATTATA

Sequences:

>Translated_230_residues
MINKADKNITDVLSQIKDGATIMIGGFGTAGQPAELIDGLINLGVKDLVIINNNAGNGDYGLAKLLKTGAVRKIICSFPR
QSDSWVFDELYHAGKIELELVPQGNLACRIQAAGMGLGAVYTPTGFGTLLAEGKETREIDGKDYVLEYPIKADFALIKAD
KGDRWGNLVYRKSARNFGPIMAMAADITIAQVSETVELGALDPEHIITPGIFVQHVVQIQPASTATTATA
>Mature_230_residues
MINKADKNITDVLSQIKDGATIMIGGFGTAGQPAELIDGLINLGVKDLVIINNNAGNGDYGLAKLLKTGAVRKIICSFPR
QSDSWVFDELYHAGKIELELVPQGNLACRIQAAGMGLGAVYTPTGFGTLLAEGKETREIDGKDYVLEYPIKADFALIKAD
KGDRWGNLVYRKSARNFGPIMAMAADITIAQVSETVELGALDPEHIITPGIFVQHVVQIQPASTATTATA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=226, Percent_Identity=42.0353982300885, Blast_Score=187, Evalue=6e-48,
Organism=Homo sapiens, GI11545841, Length=228, Percent_Identity=45.6140350877193, Blast_Score=185, Evalue=3e-47,
Organism=Escherichia coli, GI1788551, Length=217, Percent_Identity=42.8571428571429, Blast_Score=183, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=38.8185654008439, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21358325, Length=226, Percent_Identity=41.5929203539823, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24655794, Length=226, Percent_Identity=41.5929203539823, Blast_Score=173, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24530; Mature: 24530

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKADKNITDVLSQIKDGATIMIGGFGTAGQPAELIDGLINLGVKDLVIINNNAGNGDY
CCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCH
GLAKLLKTGAVRKIICSFPRQSDSWVFDELYHAGKIELELVPQGNLACRIQAAGMGLGAV
HHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCEE
YTPTGFGTLLAEGKETREIDGKDYVLEYPIKADFALIKADKGDRWGNLVYRKSARNFGPI
ECCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCEEEECCCCCCCCH
MAMAADITIAQVSETVELGALDPEHIITPGIFVQHVVQIQPASTATTATA
HHHHHCEEEEHHHHHHEECCCCHHHHCCCCHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MINKADKNITDVLSQIKDGATIMIGGFGTAGQPAELIDGLINLGVKDLVIINNNAGNGDY
CCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCH
GLAKLLKTGAVRKIICSFPRQSDSWVFDELYHAGKIELELVPQGNLACRIQAAGMGLGAV
HHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCEE
YTPTGFGTLLAEGKETREIDGKDYVLEYPIKADFALIKADKGDRWGNLVYRKSARNFGPI
ECCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCEEEECCCCCCCCH
MAMAADITIAQVSETVELGALDPEHIITPGIFVQHVVQIQPASTATTATA
HHHHHCEEEEHHHHHHEECCCCHHHHCCCCHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101; 8125318 [H]