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The map label for this gene is ygcW [C]

Identifier: 93006016

GI number: 93006016

Start: 1438035

End: 1438910

Strand: Direct

Name: ygcW [C]

Synonym: Pcryo_1188

Alternate gene names: 93006016

Gene position: 1438035-1438910 (Clockwise)

Preceding gene: 93006015

Following gene: 93006020

Centisome position: 47.0

GC content: 45.43

Gene sequence:

>876_bases
ATGTCCATGCAAAATAAATTACTGAGCCTAGTGGCAAAAAAAGCCACCAAAAGTAAAAATCAATTATTTGGCGCGGTTCA
ACCAGCACGTTATTTAAAAGGTTTAAATAAACAGCAGATTGGTCGTGGCAAAACGGTTTTAATCACGGGTGCCAGCTCAG
GGTTGGGCGAGGGCATGGCGAGATTGTTTGCTAAGCTTGGATACAACCTTGCTATTTGTGCGCGTCGTACGGATCGTTTA
GAGAGTCTACAAATAGAGCTGATGGCACAATATCCTGATATTCGTATCGAGTATCGAGTGCTAGACGTTAGTGATTATGA
TGCGATTTTTGAAGTGTTTGATGCCTTCACGGCTGACTTTGGTCATATTGATCGTGTTGTGGTCAATGCAGGCATTGGCG
AGAGCCGCCGTATTGGTAAAGGACGCTTTGATACCAACCGCCGTACGGTTGAAGTTAACTTTATCTCAGCGCTCGCGCAG
TGTGAAGCAGCGATGAGTATCTTTCGCGCACAAAATAGCGGCCATTTGGTCGTGATATCTAGTATGTCAGCGATGCGTGG
ATTACCTAAGCACTTGACTGCCTATGGTGCGAGTAAAGCAGGTTTGGCACATTTGGCAGAGGGCATCCGTGCTGATATGC
TATTGACCAAACTGCCGATCAAAGTCTCTACTATTTATCCAGGCTATATCCGTACTGAAATCAATGAAAATGCCAAGCCA
TTACCGTTTGAAGTAGATGCAGATACGGGCACCAAATCCATCGTTGCAGCGATTGAAGCTGAGGTTGATGAAGCTTGTGT
ACCCAGTCTACCATGGTCTATCGTCGGTCAAGCAATGAAGCACTTGCCATTGCAGGTGGTCAATAAAGTCAGTTAG

Upstream 100 bases:

>100_bases
AAGTCTGTAGTGGCTGGCTACTAGCGCAGATAACACCAAAGCCACATAGACAGTTGGAAGGGTTTACGTTATCTTGAAGT
TATCATTGATACATAAGAGA

Downstream 100 bases:

>100_bases
TACAAGCGACATTAATAATATCAAGACCAATAAAAGAATCCCTCTATATCAGCATATAGAGGGATTCTTTTATTGGTCTT
AATGTGTACAGATTTTAGAA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSMQNKLLSLVAKKATKSKNQLFGAVQPARYLKGLNKQQIGRGKTVLITGASSGLGEGMARLFAKLGYNLAICARRTDRL
ESLQIELMAQYPDIRIEYRVLDVSDYDAIFEVFDAFTADFGHIDRVVVNAGIGESRRIGKGRFDTNRRTVEVNFISALAQ
CEAAMSIFRAQNSGHLVVISSMSAMRGLPKHLTAYGASKAGLAHLAEGIRADMLLTKLPIKVSTIYPGYIRTEINENAKP
LPFEVDADTGTKSIVAAIEAEVDEACVPSLPWSIVGQAMKHLPLQVVNKVS

Sequences:

>Translated_291_residues
MSMQNKLLSLVAKKATKSKNQLFGAVQPARYLKGLNKQQIGRGKTVLITGASSGLGEGMARLFAKLGYNLAICARRTDRL
ESLQIELMAQYPDIRIEYRVLDVSDYDAIFEVFDAFTADFGHIDRVVVNAGIGESRRIGKGRFDTNRRTVEVNFISALAQ
CEAAMSIFRAQNSGHLVVISSMSAMRGLPKHLTAYGASKAGLAHLAEGIRADMLLTKLPIKVSTIYPGYIRTEINENAKP
LPFEVDADTGTKSIVAAIEAEVDEACVPSLPWSIVGQAMKHLPLQVVNKVS
>Mature_290_residues
SMQNKLLSLVAKKATKSKNQLFGAVQPARYLKGLNKQQIGRGKTVLITGASSGLGEGMARLFAKLGYNLAICARRTDRLE
SLQIELMAQYPDIRIEYRVLDVSDYDAIFEVFDAFTADFGHIDRVVVNAGIGESRRIGKGRFDTNRRTVEVNFISALAQC
EAAMSIFRAQNSGHLVVISSMSAMRGLPKHLTAYGASKAGLAHLAEGIRADMLLTKLPIKVSTIYPGYIRTEINENAKPL
PFEVDADTGTKSIVAAIEAEVDEACVPSLPWSIVGQAMKHLPLQVVNKVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=213, Percent_Identity=31.924882629108, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI109715829, Length=197, Percent_Identity=32.48730964467, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=31.4720812182741, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40807363, Length=218, Percent_Identity=27.5229357798165, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI157739938, Length=194, Percent_Identity=24.7422680412371, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32455239, Length=218, Percent_Identity=27.9816513761468, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031765, Length=218, Percent_Identity=27.9816513761468, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40254992, Length=196, Percent_Identity=23.469387755102, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=30.2564102564103, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789208, Length=200, Percent_Identity=29, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=204, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=241, Percent_Identity=27.8008298755187, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=235, Percent_Identity=26.3829787234043, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=239, Percent_Identity=27.6150627615063, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=235, Percent_Identity=26.8085106382979, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=194, Percent_Identity=29.8969072164948, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=241, Percent_Identity=26.1410788381743, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=29.9492385786802, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=205, Percent_Identity=27.3170731707317, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=32.48730964467, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28571387, Length=219, Percent_Identity=30.5936073059361, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI116007238, Length=197, Percent_Identity=31.4720812182741, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=28.5, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24663911, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641388, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640492, Length=237, Percent_Identity=28.2700421940928, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281364892, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007234, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648944, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356301, Length=205, Percent_Identity=27.8048780487805, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31727; Mature: 31596

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMQNKLLSLVAKKATKSKNQLFGAVQPARYLKGLNKQQIGRGKTVLITGASSGLGEGMA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHCCCCCEEEEECCCCCHHHHHH
RLFAKLGYNLAICARRTDRLESLQIELMAQYPDIRIEYRVLDVSDYDAIFEVFDAFTADF
HHHHHHCCCEEEEECHHHHHHHHHHHEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHCC
GHIDRVVVNAGIGESRRIGKGRFDTNRRTVEVNFISALAQCEAAMSIFRAQNSGHLVVIS
CCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEE
SMSAMRGLPKHLTAYGASKAGLAHLAEGIRADMLLTKLPIKVSTIYPGYIRTEINENAKP
CCHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCC
LPFEVDADTGTKSIVAAIEAEVDEACVPSLPWSIVGQAMKHLPLQVVNKVS
CCEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
SMQNKLLSLVAKKATKSKNQLFGAVQPARYLKGLNKQQIGRGKTVLITGASSGLGEGMA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHCCCCCEEEEECCCCCHHHHHH
RLFAKLGYNLAICARRTDRLESLQIELMAQYPDIRIEYRVLDVSDYDAIFEVFDAFTADF
HHHHHHCCCEEEEECHHHHHHHHHHHEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHCC
GHIDRVVVNAGIGESRRIGKGRFDTNRRTVEVNFISALAQCEAAMSIFRAQNSGHLVVIS
CCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEE
SMSAMRGLPKHLTAYGASKAGLAHLAEGIRADMLLTKLPIKVSTIYPGYIRTEINENAKP
CCHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCC
LPFEVDADTGTKSIVAAIEAEVDEACVPSLPWSIVGQAMKHLPLQVVNKVS
CCEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]