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The map label for this gene is yggW [H]

Identifier: 93005996

GI number: 93005996

Start: 1415611

End: 1416936

Strand: Direct

Name: yggW [H]

Synonym: Pcryo_1168

Alternate gene names: 93005996

Gene position: 1415611-1416936 (Clockwise)

Preceding gene: 93005991

Following gene: 93005998

Centisome position: 46.26

GC content: 42.99

Gene sequence:

>1326_bases
ATGTCAAATATCAAACCTAATCAACTGTTTCAGCAAGCAAAGCCTTTTCATGATGGTCATTCGAATGCAGTAGAAGTGAC
AGACATTCCATTGGCGTTATACATCCATATCCCGTGGTGTGTCAAAAAATGCCCTTACTGTGATTTTAATTCACATGAGC
TACCAGTTGATAGTCAGCTGTCCATGTATGATGAATATGTCGATGCATTATTGCAAGATGCTGCGATGCAGCAGGTATTG
ACCCAAGGACGTGAGATTAGCTCCATATTTATCGGCGGTGGTACGCCGTCGTTGTTGCCCATTGCTCAATACCAGCGCTT
GTTTGATGGTTTACGGAAATATTATCAATTTTCTAGCGACATCGAAATCACTATGGAGGCAAATCCAGGCACCCTTGAGC
ATGCGCCATTTGCTGAGTATTTAGAGGTGGGTATTAATCGCCTATCGATAGGTGTGCAGAGCTTTTCTGCTGAACAATTA
ACCACGCTTGGACGTATTCATAATCCTACTCAAGCGCTATCTGCAATTAAAGCAGCTCGAGAAGCTGGATTTGAGCGCGT
AAACGTGGATTTGATGCATGGACTACCAGAGCAAACCATGAGCGAGGCGTTAGACGATATTCAAATGGCACACGATGCTG
GTGCGACCCATATCTCATGGTATCAGCTGACCATTGAGCCAAATACCGTATTCTATCGCAGTCAGCCAATTTTACCCAAT
GAGGATCGCTTGGCAGATATAGAAGAATCTGGTCAGACATTATTACAGAATTTAGGCTATTGCAATTATGAGGTATCAGC
ATGGTCTGGGGCAGGGGATAAGCCTTGTCAACATAACGTCAACTACTGGCAGTTTGGTGACTATTTGGCCATTGGGGCGG
GTGCTCATGGAAAAGTCACTATTGGACAAGATATGATCGGACAAGATATCGGCAATGAGATGGCGACTGACATATGGAGT
ATTGATAGCGAAAATACTCAATCAGGTATCTATCGCTTTAGTAAATCCCGTATGCCAAAAAGTTATATAGAATATGAAGA
AGCTCATGTCCAAGATGGGGCATCAATATCAGCGCCAAAAATGGTTGGCTGGCAAGCGATTGATGAAGAGGAGTTGGTTA
GTGAGTTTATGCTTAATGCCTTACGTTTGCATGGTGGCGTAGCATGGTCGTTATTTGAAGCACGTACGGGGCTAAGTTAT
GACAGCATTGCAATACAAGTTGCTACATTAATCGAGCAAGGTCTATTGATAGATCATCCGGAACAGTTGCAACCGACAGA
ACTTGGTAAAAGGTATCTCAATCAAATATTAAGAGCATTTTTATAG

Upstream 100 bases:

>100_bases
ATTTTCTTGAAGTTGGGCTTTTTTTTACTGTGCTTAGCCGTTATCCTAGCGGTATTTTCTGCTATTGATGGCAGTTACCT
ATTTATAGATAAGTCCGCTT

Downstream 100 bases:

>100_bases
CGAAGTATGCTCGTTAAGTGTTCAGAACTTAAGCTTAATAAAAAAGGGCTTATCACATAGATGATAAGCCCTTTAAACAA
CCTAAATATTTAAAGCTTAG

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSNIKPNQLFQQAKPFHDGHSNAVEVTDIPLALYIHIPWCVKKCPYCDFNSHELPVDSQLSMYDEYVDALLQDAAMQQVL
TQGREISSIFIGGGTPSLLPIAQYQRLFDGLRKYYQFSSDIEITMEANPGTLEHAPFAEYLEVGINRLSIGVQSFSAEQL
TTLGRIHNPTQALSAIKAAREAGFERVNVDLMHGLPEQTMSEALDDIQMAHDAGATHISWYQLTIEPNTVFYRSQPILPN
EDRLADIEESGQTLLQNLGYCNYEVSAWSGAGDKPCQHNVNYWQFGDYLAIGAGAHGKVTIGQDMIGQDIGNEMATDIWS
IDSENTQSGIYRFSKSRMPKSYIEYEEAHVQDGASISAPKMVGWQAIDEEELVSEFMLNALRLHGGVAWSLFEARTGLSY
DSIAIQVATLIEQGLLIDHPEQLQPTELGKRYLNQILRAFL

Sequences:

>Translated_441_residues
MSNIKPNQLFQQAKPFHDGHSNAVEVTDIPLALYIHIPWCVKKCPYCDFNSHELPVDSQLSMYDEYVDALLQDAAMQQVL
TQGREISSIFIGGGTPSLLPIAQYQRLFDGLRKYYQFSSDIEITMEANPGTLEHAPFAEYLEVGINRLSIGVQSFSAEQL
TTLGRIHNPTQALSAIKAAREAGFERVNVDLMHGLPEQTMSEALDDIQMAHDAGATHISWYQLTIEPNTVFYRSQPILPN
EDRLADIEESGQTLLQNLGYCNYEVSAWSGAGDKPCQHNVNYWQFGDYLAIGAGAHGKVTIGQDMIGQDIGNEMATDIWS
IDSENTQSGIYRFSKSRMPKSYIEYEEAHVQDGASISAPKMVGWQAIDEEELVSEFMLNALRLHGGVAWSLFEARTGLSY
DSIAIQVATLIEQGLLIDHPEQLQPTELGKRYLNQILRAFL
>Mature_440_residues
SNIKPNQLFQQAKPFHDGHSNAVEVTDIPLALYIHIPWCVKKCPYCDFNSHELPVDSQLSMYDEYVDALLQDAAMQQVLT
QGREISSIFIGGGTPSLLPIAQYQRLFDGLRKYYQFSSDIEITMEANPGTLEHAPFAEYLEVGINRLSIGVQSFSAEQLT
TLGRIHNPTQALSAIKAAREAGFERVNVDLMHGLPEQTMSEALDDIQMAHDAGATHISWYQLTIEPNTVFYRSQPILPNE
DRLADIEESGQTLLQNLGYCNYEVSAWSGAGDKPCQHNVNYWQFGDYLAIGAGAHGKVTIGQDMIGQDIGNEMATDIWSI
DSENTQSGIYRFSKSRMPKSYIEYEEAHVQDGASISAPKMVGWQAIDEEELVSEFMLNALRLHGGVAWSLFEARTGLSYD
SIAIQVATLIEQGLLIDHPEQLQPTELGKRYLNQILRAFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=338, Percent_Identity=31.9526627218935, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1789325, Length=412, Percent_Identity=45.3883495145631, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI87082341, Length=235, Percent_Identity=34.0425531914894, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 49273; Mature: 49142

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIKPNQLFQQAKPFHDGHSNAVEVTDIPLALYIHIPWCVKKCPYCDFNSHELPVDSQL
CCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCHHHHHCCCCCCCCCCCCCCCHH
SMYDEYVDALLQDAAMQQVLTQGREISSIFIGGGTPSLLPIAQYQRLFDGLRKYYQFSSD
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
IEITMEANPGTLEHAPFAEYLEVGINRLSIGVQSFSAEQLTTLGRIHNPTQALSAIKAAR
EEEEEECCCCCCCCCCHHHHHHHCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
EAGFERVNVDLMHGLPEQTMSEALDDIQMAHDAGATHISWYQLTIEPNTVFYRSQPILPN
HCCCCEECHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEECCCCCCC
EDRLADIEESGQTLLQNLGYCNYEVSAWSGAGDKPCQHNVNYWQFGDYLAIGAGAHGKVT
CCCHHCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECCCEEEECCCCCCCEE
IGQDMIGQDIGNEMATDIWSIDSENTQSGIYRFSKSRMPKSYIEYEEAHVQDGASISAPK
ECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
MVGWQAIDEEELVSEFMLNALRLHGGVAWSLFEARTGLSYDSIAIQVATLIEQGLLIDHP
CCCCCCCCHHHHHHHHHHHHHHHHCCHHEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
EQLQPTELGKRYLNQILRAFL
CCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SNIKPNQLFQQAKPFHDGHSNAVEVTDIPLALYIHIPWCVKKCPYCDFNSHELPVDSQL
CCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCHHHHHCCCCCCCCCCCCCCCHH
SMYDEYVDALLQDAAMQQVLTQGREISSIFIGGGTPSLLPIAQYQRLFDGLRKYYQFSSD
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
IEITMEANPGTLEHAPFAEYLEVGINRLSIGVQSFSAEQLTTLGRIHNPTQALSAIKAAR
EEEEEECCCCCCCCCCHHHHHHHCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
EAGFERVNVDLMHGLPEQTMSEALDDIQMAHDAGATHISWYQLTIEPNTVFYRSQPILPN
HCCCCEECHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEECCCCCCC
EDRLADIEESGQTLLQNLGYCNYEVSAWSGAGDKPCQHNVNYWQFGDYLAIGAGAHGKVT
CCCHHCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECCCEEEECCCCCCCEE
IGQDMIGQDIGNEMATDIWSIDSENTQSGIYRFSKSRMPKSYIEYEEAHVQDGASISAPK
ECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
MVGWQAIDEEELVSEFMLNALRLHGGVAWSLFEARTGLSYDSIAIQVATLIEQGLLIDHP
CCCCCCCCHHHHHHHHHHHHHHHHCCHHEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
EQLQPTELGKRYLNQILRAFL
CCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]