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The map label for this gene is putA [H]

Identifier: 93005966

GI number: 93005966

Start: 1374382

End: 1377639

Strand: Direct

Name: putA [H]

Synonym: Pcryo_1138

Alternate gene names: 93005966

Gene position: 1374382-1377639 (Clockwise)

Preceding gene: 93005965

Following gene: 93005967

Centisome position: 44.92

GC content: 46.62

Gene sequence:

>3258_bases
ATGAACCCAGTAGAGCAATTTACCCCGCAAGAGCCGATTTTATTTAATCCTATTGATTTGTTATCACCAGAATATATTGC
TCAGTCATCAACAGAGCTACATACGCGTATATCGCCTTTGTATAGCGTGGATGAAGAGCGCTGGTTGACGCAGTTATTGC
CACTTGCCAAACCGACAGATGCCGAGCGTGACAGTGCAGCTACGCAGACGCGTCAGCTGGTTGAGCATGTGCGCAATGAT
GGTAAAGCGGTAAAAATGGTCGACTCATTATTGCTTGAGTACAGCTTGGATACCCAAGAAGGTGTTTTGCTCATGAGCTT
GGCGGAAGCCTTGATTCGTGTGCCGGACAATTATACAGCTGATGCGCTGATTCATGACAAGATGAGCGTCGCTGACTGGA
AAAAACATTTAAAAAATGACAATGGTTTTATGGTCAATGCCTCAACGTGGGGCATGATGATGACAGGTCGTGTGGTGAGC
ATCGATAGTGATACCACGGCATCTGGATTTTTGGATCGTATGACCAAAAAGATGGGTGAGCCTGTTATTCGTAGTGCTAT
GCAAAAAGCCATGCGTATCATGGGACATCAGTTTGTACTTGGCGAAACGATTGAAGGCGCTAATAAAAATAGCCAGCCAT
ATCGCAATAAAGGCTATACCTACTCATTTGATATGTTGGGTGAAGCGGCAATTACTCATAAAGATGCTGAAAAATACTTT
AATGATTATTTGCATGCTATCAAAGCCACCGCAAGTGTGAAAGTTAAAGAGGGCATGCCGAAGCCATCAGTTTCTATCAA
GCTGTCCGCATTGCATCCGCGTTATGAAGCCACCCAAGAAGAACAAGTCATGGGGCTGTTGCGTCAACGCTGCTTGTTAC
TGATTGAAGCGGCGCGTGAAGTCAATGTCGACCTCAGTATCGATGCTGAAGAAGCCGATCGTCTTGAGATATCGCTAAAA
CTATTTGAATCTCTATACCGCGACAATCTAACAGCGGATTGGGATGGTCTTGGTTTAGTTGTACAAGGTTACTCAAAGCG
TGCAATTGCTATTTTGTCTTGGCTGGCACGCTTGGCAACTGAGGTTGGCGACCGTATTCCTGTACGTCTAGTAAAGGGCG
CTTATTGGGATACAGAAATCAAGTTGGCGCAGCAAAAAGGTCTATCAGGCTATCCGGTTTGGACGCGTAAAGAAGGCACG
GATACCGCTTATCTTGCCTGCGCACGTTTCTTATTATCAGAGCATTTGCGTGGTCTTATTTGGCCACAGTTTGCAACGCA
CAATGCGCACACGCTTGCTTCAATCATGACCATGAGCTCGCACAGAGACTTTGAGTTCCAGCGTCTCCATGGTATGGGTG
ATGCGCTTTATGACCATATCTTACAAGCTTATCAAATTCCTGTGCGTATCTATGCACCGGTTGGCGCTCATAAAGATCTG
CTGCCGTATTTGGTACGTCGATTGCTCGAAAACGGTGCCAATAGCTCGTTTGTCCATCAGTTATTAGACAAGTCTTATCC
AATTGACAAGCTAACTGTACATCCGTATGACAAGCTATTAACCAATGCAACGCTACATAATCCAGATATTCCATTACCGT
TAGCTATCTATGGCGCACGCCGTGCCAGCTTTGGTCCCAATATCTTTGTAGAATCGCAGTGGATACCGTTTAAAGCAGCT
ATCGATACGCATATACACAAAACATGGTCTGCGACTTCTGTTATTAATGGCAACGCAGTCAATGACAATACGGTAGATGG
CGACACTCATCAGCTTGACAAGCAAGCTATATGTGCGCCTTGGAACCATGAAGTCATTGCCGGTGAAGTCGTCTATGCCA
ATGCTACTATCGCACAGCAAGCAATTGCGGCGGCAGTTGCTGGACAAGGCGAATGGCAAGCGGTTGCTGCTACTAAACGT
GCGGCTATATTGCGTAAAATCGCGGACTTGTATGAAGAAAACTATGCAGAGCTGATGGCATTATGCCAAGTTGAGGCAGG
TAAAACCTTACAAGACAGCATTGATGAAATCAAAGAAGCGGTTGATTTTTGCCGTTTTTATGCTGATGAAGCTGAGCGTT
TAGATGATGTTATTTATGAGTTTACCGATTTGGCAGGCAAGCCGTCGCGTCAAGTTTATAAAGCACGTGGCACCTTTATT
TGTATCAGCCCATGGAACTTTCCATTGGCTATTTATACCGGTCAAGTAGTTGCAGCACTGGCTGCAGGTAATACCGTAGT
GGCAAAACCTGCCGAACAGACGAGCTTAATCGCTCATTTCGGTGCGCAGCTTATGTATCAAGCTGGCGTGCCAGTAGAAG
CATTGCAACTCGTGATTGGCGCGGGCGACGTTGGTGCTGCATTGACTGCTGCGGACAATATCGCAGGTGTTATCTTTACA
GGTTCGACCCAAACGGCGCAGCGCATCAACCAAAGCCTAAATGCCCATGCTCAAGTCAGTGGTGAGCTGCCTGTCTTTAT
CGCCGAGACTGGCGGACAAAATGCCATGATTATGGACTCAACGGCATTGCCTGAGCAAGTGGTTAGAGATGCGGTATTAT
CTGCCTTTGGTTCAGCAGGTCAGCGCTGTTCAGCATGTCGTATCTTATGTGTACAAGAAGAGATGGCAGATGATTTGATT
GAGCTATTGCAAGGCAATATGGCTGAATTAATCGTTGGCAACCCGCTATATGCGACTACAGATGTAGGTCCTGTGATTGA
TATTGATGCCAAGCGCGGACTTGAAGCGCATATCGAACGCATGCGCGCTGAGCCAACGGCTACGATTTTGGCGCAGACAC
CGATGAGTGATAGCTCAGAGGTCAGTCAAGATCAAGCAACGTTTGTATTGCCAACGGCGATAGAAGTAAAAAGTATCGAT
GTGATCGGTGGAGAGCATTTTGGTCCTATTTTGCATGTACTGCGTTATGAAGCACGTGATCTAAATAAGCTGATTGATGC
AATCAATGCGACGGGTTTTGGTTTGACCTTGGGCATCCATAGCCGTATTGAAAACACAGTAGAGCATATCGAGCGCCGAG
CCTTTGTCGGCAATACTTATATCAACCGTAACCAAATCGGCGCGGTCGTCAACGTACAGCCGTTCGGTGGCTGCGGTCTA
TCGGGCACAGGTCCCAAAGCAGGTGGTCCACATTATGTCGCCCGTCTGATGAGCTTAACGACAGAGCAGTTGGCTAATGA
GCAAGTGGCTCTGATAGACAATACCGCTGCAACCAGTACTCAAACAATAATCGCATAA

Upstream 100 bases:

>100_bases
TTAAAAGTCACAATATCAAAAAGTCACAATATCAAAAAGTTTCAATGTTAAAAAGCCTCAGCGCATCACTTATGATGGAT
TTTCAAGTTATGGAGTTGTT

Downstream 100 bases:

>100_bases
GGAGTAGCACTATGGCGACTGAATTCAAAAAAAATCATGGCCAAGTTTGTGAAACTTGGCGTTTGCTTGGCGCAGTGAAT
CGTGCCACTTATCTGCAAGA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1085; Mature: 1085

Protein sequence:

>1085_residues
MNPVEQFTPQEPILFNPIDLLSPEYIAQSSTELHTRISPLYSVDEERWLTQLLPLAKPTDAERDSAATQTRQLVEHVRND
GKAVKMVDSLLLEYSLDTQEGVLLMSLAEALIRVPDNYTADALIHDKMSVADWKKHLKNDNGFMVNASTWGMMMTGRVVS
IDSDTTASGFLDRMTKKMGEPVIRSAMQKAMRIMGHQFVLGETIEGANKNSQPYRNKGYTYSFDMLGEAAITHKDAEKYF
NDYLHAIKATASVKVKEGMPKPSVSIKLSALHPRYEATQEEQVMGLLRQRCLLLIEAAREVNVDLSIDAEEADRLEISLK
LFESLYRDNLTADWDGLGLVVQGYSKRAIAILSWLARLATEVGDRIPVRLVKGAYWDTEIKLAQQKGLSGYPVWTRKEGT
DTAYLACARFLLSEHLRGLIWPQFATHNAHTLASIMTMSSHRDFEFQRLHGMGDALYDHILQAYQIPVRIYAPVGAHKDL
LPYLVRRLLENGANSSFVHQLLDKSYPIDKLTVHPYDKLLTNATLHNPDIPLPLAIYGARRASFGPNIFVESQWIPFKAA
IDTHIHKTWSATSVINGNAVNDNTVDGDTHQLDKQAICAPWNHEVIAGEVVYANATIAQQAIAAAVAGQGEWQAVAATKR
AAILRKIADLYEENYAELMALCQVEAGKTLQDSIDEIKEAVDFCRFYADEAERLDDVIYEFTDLAGKPSRQVYKARGTFI
CISPWNFPLAIYTGQVVAALAAGNTVVAKPAEQTSLIAHFGAQLMYQAGVPVEALQLVIGAGDVGAALTAADNIAGVIFT
GSTQTAQRINQSLNAHAQVSGELPVFIAETGGQNAMIMDSTALPEQVVRDAVLSAFGSAGQRCSACRILCVQEEMADDLI
ELLQGNMAELIVGNPLYATTDVGPVIDIDAKRGLEAHIERMRAEPTATILAQTPMSDSSEVSQDQATFVLPTAIEVKSID
VIGGEHFGPILHVLRYEARDLNKLIDAINATGFGLTLGIHSRIENTVEHIERRAFVGNTYINRNQIGAVVNVQPFGGCGL
SGTGPKAGGPHYVARLMSLTTEQLANEQVALIDNTAATSTQTIIA

Sequences:

>Translated_1085_residues
MNPVEQFTPQEPILFNPIDLLSPEYIAQSSTELHTRISPLYSVDEERWLTQLLPLAKPTDAERDSAATQTRQLVEHVRND
GKAVKMVDSLLLEYSLDTQEGVLLMSLAEALIRVPDNYTADALIHDKMSVADWKKHLKNDNGFMVNASTWGMMMTGRVVS
IDSDTTASGFLDRMTKKMGEPVIRSAMQKAMRIMGHQFVLGETIEGANKNSQPYRNKGYTYSFDMLGEAAITHKDAEKYF
NDYLHAIKATASVKVKEGMPKPSVSIKLSALHPRYEATQEEQVMGLLRQRCLLLIEAAREVNVDLSIDAEEADRLEISLK
LFESLYRDNLTADWDGLGLVVQGYSKRAIAILSWLARLATEVGDRIPVRLVKGAYWDTEIKLAQQKGLSGYPVWTRKEGT
DTAYLACARFLLSEHLRGLIWPQFATHNAHTLASIMTMSSHRDFEFQRLHGMGDALYDHILQAYQIPVRIYAPVGAHKDL
LPYLVRRLLENGANSSFVHQLLDKSYPIDKLTVHPYDKLLTNATLHNPDIPLPLAIYGARRASFGPNIFVESQWIPFKAA
IDTHIHKTWSATSVINGNAVNDNTVDGDTHQLDKQAICAPWNHEVIAGEVVYANATIAQQAIAAAVAGQGEWQAVAATKR
AAILRKIADLYEENYAELMALCQVEAGKTLQDSIDEIKEAVDFCRFYADEAERLDDVIYEFTDLAGKPSRQVYKARGTFI
CISPWNFPLAIYTGQVVAALAAGNTVVAKPAEQTSLIAHFGAQLMYQAGVPVEALQLVIGAGDVGAALTAADNIAGVIFT
GSTQTAQRINQSLNAHAQVSGELPVFIAETGGQNAMIMDSTALPEQVVRDAVLSAFGSAGQRCSACRILCVQEEMADDLI
ELLQGNMAELIVGNPLYATTDVGPVIDIDAKRGLEAHIERMRAEPTATILAQTPMSDSSEVSQDQATFVLPTAIEVKSID
VIGGEHFGPILHVLRYEARDLNKLIDAINATGFGLTLGIHSRIENTVEHIERRAFVGNTYINRNQIGAVVNVQPFGGCGL
SGTGPKAGGPHYVARLMSLTTEQLANEQVALIDNTAATSTQTIIA
>Mature_1085_residues
MNPVEQFTPQEPILFNPIDLLSPEYIAQSSTELHTRISPLYSVDEERWLTQLLPLAKPTDAERDSAATQTRQLVEHVRND
GKAVKMVDSLLLEYSLDTQEGVLLMSLAEALIRVPDNYTADALIHDKMSVADWKKHLKNDNGFMVNASTWGMMMTGRVVS
IDSDTTASGFLDRMTKKMGEPVIRSAMQKAMRIMGHQFVLGETIEGANKNSQPYRNKGYTYSFDMLGEAAITHKDAEKYF
NDYLHAIKATASVKVKEGMPKPSVSIKLSALHPRYEATQEEQVMGLLRQRCLLLIEAAREVNVDLSIDAEEADRLEISLK
LFESLYRDNLTADWDGLGLVVQGYSKRAIAILSWLARLATEVGDRIPVRLVKGAYWDTEIKLAQQKGLSGYPVWTRKEGT
DTAYLACARFLLSEHLRGLIWPQFATHNAHTLASIMTMSSHRDFEFQRLHGMGDALYDHILQAYQIPVRIYAPVGAHKDL
LPYLVRRLLENGANSSFVHQLLDKSYPIDKLTVHPYDKLLTNATLHNPDIPLPLAIYGARRASFGPNIFVESQWIPFKAA
IDTHIHKTWSATSVINGNAVNDNTVDGDTHQLDKQAICAPWNHEVIAGEVVYANATIAQQAIAAAVAGQGEWQAVAATKR
AAILRKIADLYEENYAELMALCQVEAGKTLQDSIDEIKEAVDFCRFYADEAERLDDVIYEFTDLAGKPSRQVYKARGTFI
CISPWNFPLAIYTGQVVAALAAGNTVVAKPAEQTSLIAHFGAQLMYQAGVPVEALQLVIGAGDVGAALTAADNIAGVIFT
GSTQTAQRINQSLNAHAQVSGELPVFIAETGGQNAMIMDSTALPEQVVRDAVLSAFGSAGQRCSACRILCVQEEMADDLI
ELLQGNMAELIVGNPLYATTDVGPVIDIDAKRGLEAHIERMRAEPTATILAQTPMSDSSEVSQDQATFVLPTAIEVKSID
VIGGEHFGPILHVLRYEARDLNKLIDAINATGFGLTLGIHSRIENTVEHIERRAFVGNTYINRNQIGAVVNVQPFGGCGL
SGTGPKAGGPHYVARLMSLTTEQLANEQVALIDNTAATSTQTIIA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=479, Percent_Identity=31.1064718162839, Blast_Score=193, Evalue=8e-49,
Organism=Homo sapiens, GI25777734, Length=479, Percent_Identity=31.1064718162839, Blast_Score=193, Evalue=8e-49,
Organism=Homo sapiens, GI238859541, Length=481, Percent_Identity=31.3929313929314, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI238814322, Length=429, Percent_Identity=26.8065268065268, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI153266822, Length=469, Percent_Identity=27.9317697228145, Blast_Score=147, Evalue=7e-35,
Organism=Homo sapiens, GI21614513, Length=430, Percent_Identity=26.7441860465116, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI25777732, Length=463, Percent_Identity=26.9978401727862, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI21361176, Length=444, Percent_Identity=27.027027027027, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI12007648, Length=454, Percent_Identity=28.1938325991189, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI25777724, Length=429, Percent_Identity=27.7389277389277, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25777730, Length=463, Percent_Identity=26.9978401727862, Blast_Score=133, Evalue=9e-31,
Organism=Homo sapiens, GI25777728, Length=424, Percent_Identity=27.8301886792453, Blast_Score=131, Evalue=5e-30,
Organism=Homo sapiens, GI4507229, Length=423, Percent_Identity=29.0780141843972, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI310128093, Length=385, Percent_Identity=26.7532467532467, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI310128103, Length=385, Percent_Identity=26.7532467532467, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI188035924, Length=385, Percent_Identity=26.7532467532467, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI25777721, Length=436, Percent_Identity=27.9816513761468, Blast_Score=118, Evalue=3e-26,
Organism=Homo sapiens, GI115387104, Length=428, Percent_Identity=25.4672897196262, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI310128091, Length=327, Percent_Identity=25.9938837920489, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI25952152, Length=257, Percent_Identity=31.9066147859922, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI25777726, Length=442, Percent_Identity=25.1131221719457, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI310128087, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI11095441, Length=431, Percent_Identity=25.2900232018561, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4502043, Length=330, Percent_Identity=26.3636363636364, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI238814371, Length=330, Percent_Identity=26.3636363636364, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI71773324, Length=330, Percent_Identity=26.3636363636364, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI73695881, Length=337, Percent_Identity=26.4094955489614, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI73695879, Length=337, Percent_Identity=26.4094955489614, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128099, Length=216, Percent_Identity=27.3148148148148, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI310128101, Length=216, Percent_Identity=27.3148148148148, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI310128089, Length=259, Percent_Identity=25.8687258687259, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI310128095, Length=244, Percent_Identity=25.4098360655738, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI73466520, Length=340, Percent_Identity=23.2352941176471, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI4557303, Length=340, Percent_Identity=23.2352941176471, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI206597441, Length=336, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI206597439, Length=336, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI22907049, Length=336, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI301500698, Length=280, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=1e-10,
Organism=Escherichia coli, GI1787250, Length=1077, Percent_Identity=44.3825441039926, Blast_Score=833, Evalue=0.0,
Organism=Escherichia coli, GI1788042, Length=455, Percent_Identity=29.4505494505495, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1789015, Length=442, Percent_Identity=30.7692307692308, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1787558, Length=427, Percent_Identity=29.9765807962529, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1787684, Length=454, Percent_Identity=29.0748898678414, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI87081896, Length=430, Percent_Identity=26.7441860465116, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI1787715, Length=475, Percent_Identity=29.2631578947368, Blast_Score=130, Evalue=6e-31,
Organism=Escherichia coli, GI1786504, Length=458, Percent_Identity=26.2008733624454, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87082295, Length=505, Percent_Identity=26.7326732673267, Blast_Score=107, Evalue=6e-24,
Organism=Escherichia coli, GI87081926, Length=435, Percent_Identity=24.5977011494253, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787653, Length=332, Percent_Identity=23.4939759036145, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534447, Length=501, Percent_Identity=29.3413173652695, Blast_Score=169, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=400, Percent_Identity=30, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=432, Percent_Identity=27.0833333333333, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI115532534, Length=432, Percent_Identity=29.3981481481481, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17562198, Length=438, Percent_Identity=26.9406392694064, Blast_Score=130, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25143874, Length=444, Percent_Identity=25.6756756756757, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25143876, Length=444, Percent_Identity=25.6756756756757, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=442, Percent_Identity=27.1493212669683, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25144435, Length=462, Percent_Identity=25.974025974026, Blast_Score=123, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=456, Percent_Identity=28.2894736842105, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17534119, Length=464, Percent_Identity=25.8620689655172, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564736, Length=423, Percent_Identity=25.7683215130024, Blast_Score=116, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=413, Percent_Identity=27.8450363196126, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17551164, Length=447, Percent_Identity=25.9507829977629, Blast_Score=109, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990744, Length=312, Percent_Identity=27.8846153846154, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71986308, Length=461, Percent_Identity=26.4642082429501, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=439, Percent_Identity=24.373576309795, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=388, Percent_Identity=23.1958762886598, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI32566756, Length=388, Percent_Identity=23.1958762886598, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146394, Length=388, Percent_Identity=23.1958762886598, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321826, Length=530, Percent_Identity=29.622641509434, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324950, Length=434, Percent_Identity=27.4193548387097, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320917, Length=466, Percent_Identity=28.5407725321888, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319478, Length=454, Percent_Identity=27.7533039647577, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323821, Length=451, Percent_Identity=27.2727272727273, Blast_Score=128, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323822, Length=450, Percent_Identity=27.1111111111111, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325196, Length=429, Percent_Identity=27.7389277389277, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6323757, Length=337, Percent_Identity=26.4094955489614, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668425, Length=471, Percent_Identity=32.2717622080679, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24668417, Length=471, Percent_Identity=32.2717622080679, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24668413, Length=471, Percent_Identity=32.2717622080679, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281362580, Length=464, Percent_Identity=29.0948275862069, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI62472918, Length=464, Percent_Identity=29.0948275862069, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI62472926, Length=464, Percent_Identity=29.0948275862069, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI62472936, Length=464, Percent_Identity=29.0948275862069, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21356737, Length=464, Percent_Identity=29.0948275862069, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI28574525, Length=488, Percent_Identity=25.6147540983607, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571806, Length=463, Percent_Identity=27.645788336933, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571798, Length=463, Percent_Identity=27.645788336933, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571796, Length=463, Percent_Identity=27.645788336933, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571794, Length=463, Percent_Identity=27.645788336933, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571802, Length=463, Percent_Identity=27.645788336933, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571800, Length=463, Percent_Identity=27.645788336933, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129399, Length=462, Percent_Identity=27.7056277056277, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24585660, Length=483, Percent_Identity=25.2587991718427, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24666674, Length=466, Percent_Identity=27.4678111587983, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24650465, Length=442, Percent_Identity=26.6968325791855, Blast_Score=128, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45552499, Length=416, Percent_Identity=25.9615384615385, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360303, Length=416, Percent_Identity=25.9615384615385, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281360301, Length=426, Percent_Identity=26.2910798122066, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281360299, Length=426, Percent_Identity=26.2910798122066, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281360297, Length=426, Percent_Identity=26.2910798122066, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281360295, Length=426, Percent_Identity=26.2910798122066, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24586250, Length=426, Percent_Identity=26.2910798122066, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24638876, Length=435, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24638878, Length=435, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 119051; Mature: 119051

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVEQFTPQEPILFNPIDLLSPEYIAQSSTELHTRISPLYSVDEERWLTQLLPLAKPTD
CCCCHHCCCCCCEEECCHHHCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
AERDSAATQTRQLVEHVRNDGKAVKMVDSLLLEYSLDTQEGVLLMSLAEALIRVPDNYTA
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
DALIHDKMSVADWKKHLKNDNGFMVNASTWGMMMTGRVVSIDSDTTASGFLDRMTKKMGE
CHHHHCCHHHHHHHHHHCCCCCEEEECCCCCEEEECEEEEECCCCCHHHHHHHHHHHHCC
PVIRSAMQKAMRIMGHQFVLGETIEGANKNSQPYRNKGYTYSFDMLGEAAITHKDAEKYF
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHH
NDYLHAIKATASVKVKEGMPKPSVSIKLSALHPRYEATQEEQVMGLLRQRCLLLIEAARE
HHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VNVDLSIDAEEADRLEISLKLFESLYRDNLTADWDGLGLVVQGYSKRAIAILSWLARLAT
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
EVGDRIPVRLVKGAYWDTEIKLAQQKGLSGYPVWTRKEGTDTAYLACARFLLSEHLRGLI
HHCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHC
WPQFATHNAHTLASIMTMSSHRDFEFQRLHGMGDALYDHILQAYQIPVRIYAPVGAHKDL
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHH
LPYLVRRLLENGANSSFVHQLLDKSYPIDKLTVHPYDKLLTNATLHNPDIPLPLAIYGAR
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCCCCCCEEEECCC
RASFGPNIFVESQWIPFKAAIDTHIHKTWSATSVINGNAVNDNTVDGDTHQLDKQAICAP
CCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHCCCCCCCC
WNHEVIAGEVVYANATIAQQAIAAAVAGQGEWQAVAATKRAAILRKIADLYEENYAELMA
CCCCEEEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCQVEAGKTLQDSIDEIKEAVDFCRFYADEAERLDDVIYEFTDLAGKPSRQVYKARGTFI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEE
CISPWNFPLAIYTGQVVAALAAGNTVVAKPAEQTSLIAHFGAQLMYQAGVPVEALQLVIG
EECCCCCCEEEEHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AGDVGAALTAADNIAGVIFTGSTQTAQRINQSLNAHAQVSGELPVFIAETGGQNAMIMDS
CCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCEEEECCCCCCEEEEEC
TALPEQVVRDAVLSAFGSAGQRCSACRILCVQEEMADDLIELLQGNMAELIVGNPLYATT
CCCHHHHHHHHHHHHHHCCCCCCCHHHEEEHHHHHHHHHHHHHHCCCCCEEECCCCEEEC
DVGPVIDIDAKRGLEAHIERMRAEPTATILAQTPMSDSSEVSQDQATFVLPTAIEVKSID
CCCCEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCEEEEEEEE
VIGGEHFGPILHVLRYEARDLNKLIDAINATGFGLTLGIHSRIENTVEHIERRAFVGNTY
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCE
INRNQIGAVVNVQPFGGCGLSGTGPKAGGPHYVARLMSLTTEQLANEQVALIDNTAATST
ECCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
QTIIA
CEECC
>Mature Secondary Structure
MNPVEQFTPQEPILFNPIDLLSPEYIAQSSTELHTRISPLYSVDEERWLTQLLPLAKPTD
CCCCHHCCCCCCEEECCHHHCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
AERDSAATQTRQLVEHVRNDGKAVKMVDSLLLEYSLDTQEGVLLMSLAEALIRVPDNYTA
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
DALIHDKMSVADWKKHLKNDNGFMVNASTWGMMMTGRVVSIDSDTTASGFLDRMTKKMGE
CHHHHCCHHHHHHHHHHCCCCCEEEECCCCCEEEECEEEEECCCCCHHHHHHHHHHHHCC
PVIRSAMQKAMRIMGHQFVLGETIEGANKNSQPYRNKGYTYSFDMLGEAAITHKDAEKYF
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHH
NDYLHAIKATASVKVKEGMPKPSVSIKLSALHPRYEATQEEQVMGLLRQRCLLLIEAARE
HHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VNVDLSIDAEEADRLEISLKLFESLYRDNLTADWDGLGLVVQGYSKRAIAILSWLARLAT
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
EVGDRIPVRLVKGAYWDTEIKLAQQKGLSGYPVWTRKEGTDTAYLACARFLLSEHLRGLI
HHCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHC
WPQFATHNAHTLASIMTMSSHRDFEFQRLHGMGDALYDHILQAYQIPVRIYAPVGAHKDL
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHH
LPYLVRRLLENGANSSFVHQLLDKSYPIDKLTVHPYDKLLTNATLHNPDIPLPLAIYGAR
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCCCCCCEEEECCC
RASFGPNIFVESQWIPFKAAIDTHIHKTWSATSVINGNAVNDNTVDGDTHQLDKQAICAP
CCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHCCCCCCCC
WNHEVIAGEVVYANATIAQQAIAAAVAGQGEWQAVAATKRAAILRKIADLYEENYAELMA
CCCCEEEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCQVEAGKTLQDSIDEIKEAVDFCRFYADEAERLDDVIYEFTDLAGKPSRQVYKARGTFI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEE
CISPWNFPLAIYTGQVVAALAAGNTVVAKPAEQTSLIAHFGAQLMYQAGVPVEALQLVIG
EECCCCCCEEEEHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AGDVGAALTAADNIAGVIFTGSTQTAQRINQSLNAHAQVSGELPVFIAETGGQNAMIMDS
CCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCEEEECCCCCCEEEEEC
TALPEQVVRDAVLSAFGSAGQRCSACRILCVQEEMADDLIELLQGNMAELIVGNPLYATT
CCCHHHHHHHHHHHHHHCCCCCCCHHHEEEHHHHHHHHHHHHHHCCCCCEEECCCCEEEC
DVGPVIDIDAKRGLEAHIERMRAEPTATILAQTPMSDSSEVSQDQATFVLPTAIEVKSID
CCCCEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCEEEEEEEE
VIGGEHFGPILHVLRYEARDLNKLIDAINATGFGLTLGIHSRIENTVEHIERRAFVGNTY
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCE
INRNQIGAVVNVQPFGGCGLSGTGPKAGGPHYVARLMSLTTEQLANEQVALIDNTAATST
ECCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
QTIIA
CEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]