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The map label for this gene is gpsA [H]

Identifier: 93005924

GI number: 93005924

Start: 1320568

End: 1321902

Strand: Direct

Name: gpsA [H]

Synonym: Pcryo_1096

Alternate gene names: 93005924

Gene position: 1320568-1321902 (Clockwise)

Preceding gene: 93005923

Following gene: 93005925

Centisome position: 43.16

GC content: 43.07

Gene sequence:

>1335_bases
ATGAATTTATCACAAAGTCAGTTAATTCGGATAAAACATATGATAAGCGCTAATGACAAAAGCACAGATACCAACGTAGA
CAGCACTCAAGCTGAGCAAAAAATAGCTGAAAAACAAAATAAATTGTTATCTGGTATCATTGAGCGTGCTACCAAATCTA
GTCTTGGACGTAAAAAGTTAAATCCAAGTGTGGTGGAATCTGCCGTAGCAAAAAAAATGGAAGAGATACATAAAAATCCG
ACCAAGCTGCGTTTAGTAGTATTAGGCGGCGGTAGCTTTGGCACCGCCATGGCAAACTTAGCGGCACGCAATGGCTGCGA
TACCACGCTGTGGGTGCGCAACAAGCGTACGGTCAAAGCGATGGCAAAATCGCAAATGAATAAAAAATACTTGCCAGGCT
ATAAGCTTGATGACCGCCTAAAATACAGTCATGAGCTGCAAGCCGCAGTCAAAGATACGGATATTATCTTCATTGCCGTA
CCGGGATTGGCGTTTCGCGAAACGCTTAAAAGTATCGCCCCTTTTATTAGTGGGCAGTCTATTGTTTCTTTGACCAAAGG
GATGGAAAAAGACACTTTTTCTCTGATGAGTGACATCATCAAAGACGAGCTACCTGAAGTAAATTTTGGCGTGATGTCTG
GTCCAAATCTTGCTATAGAAATTATGAAAAACATGCCTTCTGCCACGGTAATCGCTAGTGAATCTGAACCACTGCGTCAT
GCCGTACAAGCGGCATTACATAGTGCTTTCTTTAGAGTATTTGCTAGTGATGATATCCGCGGTGTTGAGCTTGGCGGCGC
GTTAAAGAATATTTATGCCATTGCTATGGGTATGGCAGCTGCTTACGAGGTTGGTGAAAATACCAAAGCGATGATATTGA
CCCGTGGCTTAGCAGAGATGAGTCGCTTTGGTGTACATGCTGGTGCCAATCCGCTGACCTTTTTAGGGTTATCAGGTGTC
GGGGATTTATATGCCACTTGTAGCTCCGAGTTAAGTCGTAATTATCGTATTGGTAATATGCTTGGTCGTGGTATGACGAT
TGATGCAGCGGTCAAAAAATTGGGACAAACTGCTGAAGGTGTGAATACCATTCAGCAAGTACATGAAAAAGCCACTAAAG
AAGGCATTTATATGCCTATTACTCATGCGTTATATGCCGTCATTTATGAAGACAAAGCGGCGCTTGGTGTTGCCCTGCAT
TTGATGGAAGCAGGCTTTCGTAGTGATGTTGAATTTGTCATGGAGCACGACCACAGTAATGCTTCGCTGACCGCGCAAAT
GCAAACTGCAAACAGCCAATCAAAAGAGGATAAAAGTAAGCAGGGTAATAAGTAA

Upstream 100 bases:

>100_bases
AGAATGGCTGTTTGGCTGAGCTAGTAGCCTAAAAAATACTGTTAATTTGTACAAATAATTGTTCATACATTTTGCTGCGC
TCACTGTATACTCAGCATAA

Downstream 100 bases:

>100_bases
TAAGAGGTTGTTAGCGCAATAGCAATAGCGTGTCACTAAAAGAGAGTTACTTATAATTTGAACTGGCGATATAACAACAA
TAAAAAAGGCTGATAACTTA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNLSQSQLIRIKHMISANDKSTDTNVDSTQAEQKIAEKQNKLLSGIIERATKSSLGRKKLNPSVVESAVAKKMEEIHKNP
TKLRLVVLGGGSFGTAMANLAARNGCDTTLWVRNKRTVKAMAKSQMNKKYLPGYKLDDRLKYSHELQAAVKDTDIIFIAV
PGLAFRETLKSIAPFISGQSIVSLTKGMEKDTFSLMSDIIKDELPEVNFGVMSGPNLAIEIMKNMPSATVIASESEPLRH
AVQAALHSAFFRVFASDDIRGVELGGALKNIYAIAMGMAAAYEVGENTKAMILTRGLAEMSRFGVHAGANPLTFLGLSGV
GDLYATCSSELSRNYRIGNMLGRGMTIDAAVKKLGQTAEGVNTIQQVHEKATKEGIYMPITHALYAVIYEDKAALGVALH
LMEAGFRSDVEFVMEHDHSNASLTAQMQTANSQSKEDKSKQGNK

Sequences:

>Translated_444_residues
MNLSQSQLIRIKHMISANDKSTDTNVDSTQAEQKIAEKQNKLLSGIIERATKSSLGRKKLNPSVVESAVAKKMEEIHKNP
TKLRLVVLGGGSFGTAMANLAARNGCDTTLWVRNKRTVKAMAKSQMNKKYLPGYKLDDRLKYSHELQAAVKDTDIIFIAV
PGLAFRETLKSIAPFISGQSIVSLTKGMEKDTFSLMSDIIKDELPEVNFGVMSGPNLAIEIMKNMPSATVIASESEPLRH
AVQAALHSAFFRVFASDDIRGVELGGALKNIYAIAMGMAAAYEVGENTKAMILTRGLAEMSRFGVHAGANPLTFLGLSGV
GDLYATCSSELSRNYRIGNMLGRGMTIDAAVKKLGQTAEGVNTIQQVHEKATKEGIYMPITHALYAVIYEDKAALGVALH
LMEAGFRSDVEFVMEHDHSNASLTAQMQTANSQSKEDKSKQGNK
>Mature_444_residues
MNLSQSQLIRIKHMISANDKSTDTNVDSTQAEQKIAEKQNKLLSGIIERATKSSLGRKKLNPSVVESAVAKKMEEIHKNP
TKLRLVVLGGGSFGTAMANLAARNGCDTTLWVRNKRTVKAMAKSQMNKKYLPGYKLDDRLKYSHELQAAVKDTDIIFIAV
PGLAFRETLKSIAPFISGQSIVSLTKGMEKDTFSLMSDIIKDELPEVNFGVMSGPNLAIEIMKNMPSATVIASESEPLRH
AVQAALHSAFFRVFASDDIRGVELGGALKNIYAIAMGMAAAYEVGENTKAMILTRGLAEMSRFGVHAGANPLTFLGLSGV
GDLYATCSSELSRNYRIGNMLGRGMTIDAAVKKLGQTAEGVNTIQQVHEKATKEGIYMPITHALYAVIYEDKAALGVALH
LMEAGFRSDVEFVMEHDHSNASLTAQMQTANSQSKEDKSKQGNK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=333, Percent_Identity=28.2282282282282, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI33695088, Length=343, Percent_Identity=26.2390670553936, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1790037, Length=321, Percent_Identity=38.3177570093458, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI32564399, Length=337, Percent_Identity=27.299703264095, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=346, Percent_Identity=26.878612716763, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32564403, Length=346, Percent_Identity=26.878612716763, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17507425, Length=315, Percent_Identity=26.984126984127, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI193210134, Length=329, Percent_Identity=25.8358662613982, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320181, Length=374, Percent_Identity=29.144385026738, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324513, Length=355, Percent_Identity=28.169014084507, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI22026922, Length=333, Percent_Identity=25.2252252252252, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17136204, Length=340, Percent_Identity=29.1176470588235, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17136200, Length=340, Percent_Identity=29.1176470588235, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17136202, Length=340, Percent_Identity=29.1176470588235, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI45551945, Length=300, Percent_Identity=24.6666666666667, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362270, Length=300, Percent_Identity=24.6666666666667, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648969, Length=243, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 48233; Mature: 48233

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSQSQLIRIKHMISANDKSTDTNVDSTQAEQKIAEKQNKLLSGIIERATKSSLGRKKL
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NPSVVESAVAKKMEEIHKNPTKLRLVVLGGGSFGTAMANLAARNGCDTTLWVRNKRTVKA
CHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEEECCCHHHHH
MAKSQMNKKYLPGYKLDDRLKYSHELQAAVKDTDIIFIAVPGLAFRETLKSIAPFISGQS
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCH
IVSLTKGMEKDTFSLMSDIIKDELPEVNFGVMSGPNLAIEIMKNMPSATVIASESEPLRH
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHH
AVQAALHSAFFRVFASDDIRGVELGGALKNIYAIAMGMAAAYEVGENTKAMILTRGLAEM
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHH
SRFGVHAGANPLTFLGLSGVGDLYATCSSELSRNYRIGNMLGRGMTIDAAVKKLGQTAEG
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCHHHH
VNTIQQVHEKATKEGIYMPITHALYAVIYEDKAALGVALHLMEAGFRSDVEFVMEHDHSN
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC
ASLTAQMQTANSQSKEDKSKQGNK
CEEEEEEHHCCCCHHHHHHHCCCC
>Mature Secondary Structure
MNLSQSQLIRIKHMISANDKSTDTNVDSTQAEQKIAEKQNKLLSGIIERATKSSLGRKKL
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NPSVVESAVAKKMEEIHKNPTKLRLVVLGGGSFGTAMANLAARNGCDTTLWVRNKRTVKA
CHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEEECCCHHHHH
MAKSQMNKKYLPGYKLDDRLKYSHELQAAVKDTDIIFIAVPGLAFRETLKSIAPFISGQS
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCH
IVSLTKGMEKDTFSLMSDIIKDELPEVNFGVMSGPNLAIEIMKNMPSATVIASESEPLRH
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHH
AVQAALHSAFFRVFASDDIRGVELGGALKNIYAIAMGMAAAYEVGENTKAMILTRGLAEM
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHH
SRFGVHAGANPLTFLGLSGVGDLYATCSSELSRNYRIGNMLGRGMTIDAAVKKLGQTAEG
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCHHHH
VNTIQQVHEKATKEGIYMPITHALYAVIYEDKAALGVALHLMEAGFRSDVEFVMEHDHSN
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC
ASLTAQMQTANSQSKEDKSKQGNK
CEEEEEEHHCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA